Metabonomics approach to assessing the modulatory effects of St John's Wort, ginsenosides, and clomipramine in experimental depression

Journal of Proteome Research

Volumn 11, Issue 12, 2012, Pages 6223-6230

  Wang, Xiaoyan ^a   Zeng, Chuiyu ^b   Lin, Jingchao ^a   Chen, Tianlu ^a   Zhao, Tie ^a   Jia, Zhiying ^a   Xie, Xie ^a   Qiu, Yunping ^c   Su, Mingming ^c   Jiang, Tao ^d   Zhou, Mingmei ^d   Zhao, Aihua ^a   Jia, Wei ^a,c  

^a Shanghai Jiao Tong University   (China)

^b S Pharma Grp Bus U Antibiot   (China)

^c UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^d SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

brain; chronic unpredictable mild stress; clomipramine; gas chromatography mass spectrometry; ginsenoside; metabonomics; serum; St John's Wort; urine

Indexed keywords

CLOMIPRAMINE; GINSENOSIDE; HYPERICUM PERFORATUM EXTRACT; STRESS HORMONE; SUCROSE;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BODY WEIGHT; CARBOHYDRATE INTAKE; CONTROLLED STUDY; DEPRESSION; FOOD INTAKE; HORMONE BLOOD LEVEL; MASS FRAGMENTOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN; THYMUS;

ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BODY WEIGHT; CLOMIPRAMINE; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; FOOD DEPRIVATION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GINSENOSIDES; HYPERICUM; MALE; METABOLOME; METABOLOMICS; MULTIVARIATE ANALYSIS; PHENOTYPE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; STRESS, PSYCHOLOGICAL; SUCROSE; SWIMMING; THYMUS GLAND;

RATTUS;

EID: 84870878531     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300891v     Document Type: Article

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