Application of a mixture model for determining the cutoff threshold for activity in high-throughput screening

Computational Statistics and Data Analysis

Volumn 51, Issue 8, 2007, Pages 4002-4012

  Tong, Donald D M ^a   Buxser, Stephen ^a   Vidmar, Thomas J ^b  

^a PharmOptima   (United States)

^b PFIZER INC   (United States)

Author keywords

Cutoff threshold; Gamma distribution; High throughput screening; Mixture model

Indexed keywords

BIOASSAY; CUTOFF FREQUENCY; DATA REDUCTION; ENZYMES; STATISTICAL METHODS; THROUGHPUT;

CUTOFF THRESHOLD; GAMMA DISTRIBUTION; HIGH THROUGHPUT SCREENING (HTS); MIXTURE MODEL;

THRESHOLD LOGIC;

EID: 33947638491     PISSN: 01679473     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.csda.2006.12.014     Document Type: Article

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