Three-dimensional molecular reconstruction of rat heart with mass spectrometry imaging

Analytical and Bioanalytical Chemistry

Volumn 404, Issue 10, 2012, Pages 2927-2938

  Fornai, Lara ^a,b   Angelini, Annalisa ^a   Klinkert, Ivo ^b   Giskes, Frans ^b   Kiss, Andras ^b   Eijkel, Gert ^b   Hove, Erika A Amstalden Van ^b   Klerk, Leendert A ^b   Fedrigo, Marny ^a   Pieraccini, Giuseppe ^c   Moneti, Gloriano ^c   Valente, Marialuisa ^a   Thiene, Gaetano ^a   Heeren, Ron M A ^b,d  

^a UNIVERSITY OF PADOVA   (Italy)

^b FOM INSTITUTE AMOLF   (Netherlands)

^c UNIVERSITY OF FLORENCE   (Italy)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

3D molecular reconstruction; Heart; Imaging; Secondary ion mass spectrometry

Indexed keywords

3D RECONSTRUCTION; ANIMAL MODEL; CARDIO-VASCULAR DISEASE; CROSS-SPECIES; HEART MODEL; HEART VOLUMES; HIGH RESOLUTION; HUMAN HEART; METAL-ASSISTED SIMS; MOLECULAR BASIS; MOLECULAR SIGNATURES; MOUSE HEART; PATHOPHYSIOLOGICAL; RAT HEART; SIMS IMAGING; STRUCTURAL IMAGING;

HEART; IMAGE RECONSTRUCTION; IMAGING TECHNIQUES; MOLECULAR IMAGING; PRINCIPAL COMPONENT ANALYSIS; SECONDARY ION MASS SPECTROMETRY; THREE DIMENSIONAL COMPUTER GRAPHICS;

THREE DIMENSIONAL;

ANIMAL; ARTICLE; COMPUTER PROGRAM; HEART; HEART MUSCLE; HISTOLOGY; HUMAN; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR IMAGING; MOUSE; PRINCIPAL COMPONENT ANALYSIS; RAT; THREE DIMENSIONAL IMAGING; ULTRASTRUCTURE;

ANIMALS; HEART; HUMANS; IMAGING, THREE-DIMENSIONAL; MICE; MOLECULAR IMAGING; MYOCARDIUM; PRINCIPAL COMPONENT ANALYSIS; RATS; SOFTWARE; SPECTROMETRY, MASS, SECONDARY ION;

ANIMALIA; RATTUS;

EID: 84870873358     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-012-6451-3     Document Type: Article

References (37)

1. McGregor E, Dunn MJ (2006) Proteomics of the heart unraveling disease. Circ Res 98:309-321
2. Mueller DR, Voshol H, Waldt A, Van Oostrum J (2007) LCMALDI MS and MS/MS - an efficient tool in proteome analysis. Subcell Biochem 43:355-380
3. Li L, Garden RW, Sweedler JV (2000) Single-cell MALDI: a new tool for direct peptide profiling. Trends Biotechnol 18:151-160
4. Suzuki T, Nagai R (2007) Cardiovascular proteomic analysis. J Chromatogr B Analyt Technol Biomed Life Sci 855:28-34
5. Ping P (2009) Getting to the heart of proteomics. N Engl J Med 360:532-534
6. Dunn MJ, Corbett JM, Wheeler CH (1997) HSC-2DPAGE and the two dimensional gel electrophoresis database of dog heart proteins. Electrophoresis 18:2795-2802
7. Li XP, Pleissner KP, Scheler C, Regitz-Zagrosek V, Salnikow J, Jungblut PR (1999) A two-dimensional electrophoresis database of rat heart proteins. Electrophoresis 20:891-897
8. Russell JC (2003) Of mice and men, rats and atherosclerosis. Cardiovasc Res 59:810-811
9. Chaurand P, Norris JL, Cornett DS, Mobley JA, Caprioli RM (2006) New developments in profiling and imaging of proteins from tissues by MALDI mass spectrometry. J Proteome Res 5:2889-2900
10. Heeren RMA, McDonnell LA, Amstalden E, Luxembourg SL, Altelaar AFM, Piersma SR (2006) Why don't biologists use SIMS? A critical evaluation of imaging MS. Appl Surf Sci 252:6827-6835
11. Chughtai K, Heeren RM (2010) Mass spectrometric imaging for biomedical tissue analysis. Chem Rev 110:3237-3277
12. McQuaw CM, Sostarecz AG, Zheng L, Ewing AG, Winograd N (2006) Investigating lipid interactions and process of raft formation in cellular membranes using ToF-SIMS. Appl Surf Sci 252:6716-6718
13. Heeren RMA, Kukrer-Kaletas B, Taban IM, MacAleese L, McDonnell LA (2008) Quality of surface: the influence of sample preparation on MS-based biomolecular tissue imaging with MALDI-MS and (ME-)SIMS. Appl Surf Sci 255:1289- 1297
14. Amstalden van Hove ER, Blackwell TR, Klinkert I, Eijkel GB, Heeren RM, Glunde K (2010) Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models. Cancer Res 70:9012-9021
15. Pól J, Strohalm M, Havlíček V, Volný M (2010) Molecular mass spectrometry imaging in biomedical and life science research. Histochem Cell Biol 134:423-443
16. MacAleese L, Duursma MC, Klerk LA, Fisher G, Heeren RMA (2011) Protein identification with liquid chromatography and matrix enhanced secondary ion mass spectrometry (LC-ME-SIMS). J Proteomics 74:993-1001
17. Klerk LA, Broersen A, Fletcher IW, van Liere R, Heeren RMA (2007) Extended data analysis strategies for high resolution imaging MS: new methods to deal with extremely large image hyperspectral datasets. Int J Mass Spectrom 260:222-236
18. Smit FA, van Liere R, Fornai L, Heeren RMA (2010) An interactive, multi-modal approach to analysing high-resolution image mass spectrometry data. Proceedings of Vision, Modeling and Visualization (VMV) 283-289
19. Malmberg P, Jennische E, Nilsson D, Nygren H (2011) Highresolution, imaging TOF-SIMS: novel applications in medical research. Anal Bioanal Chem 399:2711-2718
20. Passarelli M,Winograd N (2011) Lipid imaging with time-of-flight secondary ion mass spectrometry (ToF-SIMS). Biochim Biophys Acta 1811:976-990
21. Malmberg P, Börner K, Chen Y, Friberg P, Hagenhoff B, Månsson J, Nygren H (2007) Localization of lipids in the aortic wall with imaging TOF-SIMS. Biochim Biophys Acta 1771:185-195
22. Tahallah N, Brunelle A, De La Porte S, Laprévote O (2008) Lipid mapping in human dystrophic muscle by cluster-time-offlight secondary ion mass spectrometry imaging. J Lipid Res 49:438-454
23. Lands WE, Hart P (1965) Metabolism of glycerolipids VI specificities of acyl coenzyme A: phospholipids acyltransfererases. J Biol Chem 240:1905-1911
24. Crecelius AC, Cornett DS, Caprioli RM, Williams B, Dawant BM, Bodenheimer B (2005) Three-dimensional visualisation of protein expression in mouse brain structures using imaging mass spectrometry. J Am Soc Mass Spec 16:1093-1099
25. Sal'manovich VS (1962) The distribution of potassium and sodium in the heart of various animals. Biull Eksp Biol Med 54:58-62
26. Lopaschuk GD, Ussher JR, Folmes CD, Jaswal JS, Stanley WC (2010) Myocardial fatty acid metabolism in health and disease. Physiol Rev 90:207-258
27. Braunwald E (2008) Biomarkers in heart failure. N Engl J Med 358:2148-2159
28. Sharma S, Adrogue J, Golfman L (2004) Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart. FASEB J 18:1692-1700
29. Charnock JS, Abeywardena MY, Mcmurchie EJ (1984) The composition of cardiac phospholipids in rats fed different lipid supplements. Lipids 19:206-213
30. Gurcan MN, Boucheron L, Can A, Madabhushi A, Rajpoot N, Yener B (2009) Histopathological image analysis: a review. IEEE Rev Biomed Eng 2:147-171
31. Touboul D, Brunelle A, Halgand F, De La Porte S, Laprevote O (2005) Lipid imaging by gold cluster time-of-flight secondary ion mass spectrometry: application to Duchenne muscular dystrophy. J Lipid Res 46:1388-1395
32. Nygren H, Johansson BR, Malmberg P (2004) Bioimaging TOFSIMS of tissues by gold ion bombardment of a silver-coated thin section. Microsc Res Tech 65:282-286
33. Richter K, Nygren H, Malmberg P, Hagenhoff B (2007) Localization of fatty acids with selective chain length by imaging time-of-flight secondary ion mass spectrometry. Microsc Res Tech 70:640-647
34. Borner K, Malmberg P, Mansson JE, Nygren H (2007) Molecular imaging of lipids in cells and tissues. Int J Mass Spectrom 260:128-136
35. Ayciriex S, Touboul D, Brunelle A, Laprevote O (2011) Time-offlight secondary ion mass spectrometer: a novel tool for lipid imaging. Clin Lipidol 6:437-445
36. Kotze HL, Armitage EG, Fletcher JS, Henderson A, Williams KJ, Lockyer NP, Vickerman JC (2012) ToF-SIMS as a tool for metabolic profiling small biomolecules in cancer systems. Surf Interface Anal. doi:10.1002/sia.5055
37. ACCF/ACR/AHA/NASCI/SCMR (2010) Expert consensus document on cardiovascular magnetic resonance. A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. J Am Coll Cardiol 55:2614-2662