The streptococcal hemoprotein receptor: A moonlighting protein or a virulence factor?

Virulence

Volumn 3, Issue 7, 2012, Pages

  Eichenbaum, Zehava ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; HEME; HEMOGLOBIN; HEMOPROTEIN; IRON; LAMININ; RECEPTOR PROTEIN; VIRULENCE FACTOR;

BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; DELETION MUTANT; EDITORIAL; IN VITRO STUDY; NONHUMAN; PATHOGENESIS; PROTEIN PROTEIN INTERACTION; STREPTOCOCCUS GROUP A; ANIMAL; FEMALE; HUMAN; METABOLISM; PATHOGENICITY; STREPTOCOCCUS PYOGENES; NOTE;

ANIMALS; FEMALE; HEMEPROTEINS; HUMANS; IRON; STREPTOCOCCUS PYOGENES; VIRULENCE FACTORS;

EID: 84870869691     PISSN: 21505594     EISSN: 21505608     Source Type: Journal    
DOI: None     Document Type: Editorial

References (33)

1. Cunningham MW. Pathogenesis of group A streptococcal infections and their sequelae. Adv Exp Med Biol 2008; 609:29-42; PMID:18193655; http://dx. doi.org/10.1007/978-0-387-73960-1_3
2. Guilherme L, Kalil J. Rheumatic fever and rheumatic heart disease: cellular mechanisms leading autoimmune reactivity and disease. J Clin Immunol 2010; 30:17-23; PMID:19802690; http://dx.doi.org/10.1007/s10875-009-9332-6
3. Hoge CW, Schwartz B, Talkington DF, Breiman RF, MacNeill EM, Englender SJ. The changing epidemiology of invasive group A streptococcal infections and the emergence of streptococcal toxic shock-like syndrome. A retrospective population-based study. JAMA 1993; 269:384-9; PMID:8418346; http://dx.doi.org/10.1001/jama.1993.03500030082037
4. Bisno AL. The resurgence of acute rheumatic fever in the United States. Annu Rev Med 1990; 41:319-29; PMID:2184733; http://dx.doi.org/10.1146/annurev. me.41.020190.001535
5. Bessen DE. Population biology of the human restricted pathogen, Streptococcus pyogenes. Infect Genet Evol 2009; 9:581-93; PMID:19460325; http://dx.doi.org/10.1016/j.meegid.2009.03.002
6. Lancefield RC. The Antigenic Complex of Streptococcus Haemolyticus: I. Demonstration of a Type-Specific Substance in Extracts of Streptococcus Haemolyticus. J Exp Med 1928; 47:91-103; PMID: 19869404; http://dx.doi.org/10.1084/jem.47.1.91
7. Lancefield RC, Dole VP. The Properties of T Antigens Extracted from Group a Hemolytic Streptococci. J Exp Med 1946; 84:449-71; PMID:19871581; http://dx. doi.org/10.1084/jem.84.5.449
8. Mora M, Bensi G, Capo S, Falugi F, Zingaretti C, Manetti AG, et al. Group A Streptococcus produce pilus-like structures containing protective antigens and Lancefield T antigens. Proc Natl Acad Sci U S A 2005; 102:15641-6; PMID:16223875; http://dx.doi.org/10. 1073/pnas.0507808102
9. Beall B, Facklam R, Thompson T. Sequencing emmspecific PCR products for routine and accurate typing of group A streptococci. J Clin Microbiol 1996; 34: 953-8; PMID:8815115
10. Johnson DR, Kaplan EL, VanGheem A, Facklam RR, Beall B. Characterization of group A streptococci (Streptococcus pyogenes): correlation of M-protein and emm-gene type with T-protein agglutination pattern and serum opacity factor. J Med Microbiol 2006; 55:157-64; PMID:16434707; http://dx.doi.org/10.1099/jmm.0.46224-0
11. Falugi F, Zingaretti C, Pinto V, Mariani M, Amodeo L, Manetti AG, et al. Sequence variation in group A Streptococcus pili and association of pilus backbone types with lancefield T serotypes. J Infect Dis 2008; 198:1834-41; PMID:18928376; http://dx.doi.org/10. 1086/593176
12. Lynskey NN, Lawrenson RA, Sriskandan S. New understandings in Streptococcus pyogenes. Curr Opin Infect Dis 2011; 24:196-202; PMID:21415743; http://dx.doi.org/10.1097/QCO.0b013e3283458f7e
13. Schwartz B, Facklam RR, Breiman RF. Changing epidemiology of group A streptococcal infection in the USA. Lancet 1990; 336:1167-71; PMID:1978035; http://dx.doi.org/10.1016/0140-6736(90)92777-F
14. Aziz RK, Kotb M. Rise and persistence of global M1T1 clone of Streptococcus pyogenes. Emerg Infect Dis 2008; 14:1511-7; PMID:18826812; http://dx.doi.org/10.3201/eid1410.071660
15. Beres SB, Carroll RK, Shea PR, Sitkiewicz I, Martinez-Gutierrez JC, Low DE, et al. Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics. Proc Natl Acad Sci U S A 2010; 107:4371-6; PMID:20142485; http://dx.doi. org/10.1073/pnas.0911295107
16. Maamary PG, Ben Zakour NL, Cole JN, Hollands A, Aziz RK, Barnett TC, et al. Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone. FASEB J 2012; 26:4675-84; PMID:22878963; http://dx.doi.org/10.1096/fj.12-212142
17. Garcia AF, Abe LM, Erdem G, Cortez CL, Kurahara D, Yamaga K. An insert in the covS gene distinguishes a pharyngeal and a blood isolate of Streptococcus pyogenes found in the same individual. Microbiology 2010; 156:3085-95; PMID:20634239; http://dx.doi. org/10.1099/mic.0.042614-0
18. Hollands A, Pence MA, Timmer AM, Osvath SR, Turnbull L, Whitchurch CB, et al. Genetic switch to hypervirulence reduces colonization phenotypes of the globally disseminated group A streptococcus M1T1 clone. J Infect Dis 2010; 202:11-9; PMID:20507231; http://dx.doi.org/10.1086/653124
19. Hasegawa T, Okamoto A, Kamimura T, Tatsuno I, Hashikawa SN, Yabutani M, et al. Detection of invasive protein profile of Streptococcus pyogenes M1 isolates from pharyngitis patients. APMIS 2010; 118: 167-78; PMID:20132182; http://dx.doi.org/10.1111/j.1600-0463.2009.02574.x
20. Walker MJ, Hollands A, Sanderson-Smith ML, Cole JN, Kirk JK, Henningham A, et al. DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nat Med 2007; 13:981-5; PMID:17632528; http://dx.doi.org/10.1038/nm1612
21. Dahesh S, Nizet V, Cole JN. Study of streptococcal hemoprotein receptor (Shr) in iron acquisition and virulence of M1T1 group A Streptococcus. Virulence 2012; In press; PMID:23076332; http://dx.doi.org/10.4161/viru.21933
22. Bates CS, Montañez GE, Woods CR, Vincent RM, Eichenbaum Z. Identification and characterization of a Streptococcus pyogenes operon involved in binding of hemoproteins and acquisition of iron. Infect Immun 2003; 71:1042-55; PMID:12595414; http://dx.doi. org/10.1128/IAI.71.3.1042-1055.2003
23. Sook BR, BlockDR, Sumithran S, MontañezGE, Rodgers KR, Dawson JH, et al. Characterization of SiaA, a streptococcal heme-binding protein associated with a heme ABC transport system. Biochemistry 2008; 47:2678-88; PMID:18247478; http://dx.doi.org/10.1021/bi701604y
24. Ouattara M, Cunha EB, Li X, Huang YS, Dixon D, Eichenbaum Z. Shr of group A streptococcus is a new type of composite NEAT protein involved in sequestering haem from methaemoglobin. Mol Microbiol 2010; 78:739-56; PMID:20807204; http://dx.doi.org/10.1111/j.1365-2958.2010.07367.x
25. Nygaard TK, Blouin GC, Liu M, Fukumura M, Olson JS, Fabian M, et al. The mechanism of direct heme transfer from the streptococcal cell surface protein Shp to HtsA of the HtsABC transporter. J Biol Chem 2006; 281:20761-71; PMID:16717094; http://dx.doi.org/10.1074/jbc.M601832200
26. Andrade MA, Ciccarelli FD, Perez-Iratxeta C, Bork P. NEAT: a domain duplicated in genes near the components of a putative Fe3+ siderophore transporter from Gram-positive pathogenic bacteria. Genome Biol 2002; 3:H0047; PMID:12225586; http://dx.doi.org/10.1186/gb-2002-3-9-research0047
27. Fisher M, Huang YS, Li X, McIver KS, Toukoki C, Eichenbaum Z. Shr is a broad-spectrum surface receptor that contributes to adherence and virulence in group A streptococcus. Infect Immun 2008; 76:5006-15; PMID: 18710861; http://dx.doi.org/10.1128/IAI.00300-08
28. Nobbs AH, Lamont RJ, Jenkinson HF. Streptococcus adherence and colonization[Table of Contents.]. Microbiol Mol Biol Rev 2009; 73:407-50; PMID: 19721085; http://dx.doi.org/10.1128/MMBR.00014-09
29. Nobles CL, Maresso AW. The theft of host heme by Grampositive pathogenic bacteria. Metallomics 2011; 3:788-96; PMID:21725569; http://dx.doi.org/10.1039/c1mt00047k
30. Mayfield JA, Dehner CA, DuBois JL. Recent advances in bacterial heme protein biochemistry. Curr Opin Chem Biol 2011; 15:260-6; PMID:21339081; http://dx.doi.org/10.1016/j.cbpa.2011.02.002
31. Clarke SR, Wiltshire MD, Foster SJ. IsdA of Staphylococcus aureus is a broad spectrum, iron-regulated adhesin. Mol Microbiol 2004; 51:1509-19; PMID:14982642; http://dx. doi.org/10.1111/j.1365-2958.2003.03938.x
32. Clarke SR, Mohamed R, Bian L, Routh AF, Kokai-Kun JF, Mond JJ, et al. The Staphylococcus aureus surface protein IsdA mediates resistance to innate defenses of human skin. Cell Host Microbe 2007; 1: 199-212; PMID:18005699; http://dx.doi.org/10. 1016/j.chom.2007.04.005
33. Huang YS, Fisher M, Nasrawi Z, Eichenbaum Z. Defense from the Group A Streptococcus by active and passive vaccination with the streptococcal hemoprotein receptor. J Infect Dis 2011; 203:1595-601; PMID: 21592989; http://dx.doi.org/10.1093/infdis/jir149