Shr is a broad-spectrum surface receptor that contributes to adherence and virulence in group A streptococcus

Infection and Immunity

Volumn 76, Issue 11, 2008, Pages 5006-5015

  Fisher, Morly ^a   Huang, Ya Shu ^b   Li, Xueru ^b   McIver, Kevin S ^c   Toukoki, Chadia ^b   Eichenbaum, Zehava ^b  

^a ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

^b GEORGIA STATE UNIVERSITY   (United States)

^c Bldg 142   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL PROTEIN; FIBRONECTIN; HEMOPROTEIN; LAMININ; PROTEIN SHR; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CELL ADHESION; CELL MEMBRANE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; IMMUNE RESPONSE; LACTOCOCCUS LACTIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; STREPTOCOCCUS GROUP A; ZEBRA FISH;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL ADHESION; BACTERIAL OUTER MEMBRANE PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES; ZEBRAFISH;

EID: 55849096919     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00300-08     Document Type: Article

References (54)

1. Abbot, E. L., W. D. Smith, G. P. Siou, C. Chiriboga, R. J. Smith, J. A. Wilson, B. H. Hirst, and M. A. Kehoe. 2007. Pili mediate specific adhesion of Streptococcus pyogenes to human tonsil and skin. Cell. Microbiol. 9:1822-1833.
2. Andrade, M. A., F. D. Ciccarelli, C. Perez-Iratxeta, and P. Bork. 2002. NEAT: a domain duplicated in genes near the components of a putative Fe3+ siderophore transporter from gram-positive pathogenic bacteria. Genome Biol. 3:RESEARCH0047.
3. Barnett, T. C., A. R. Patel, and J. R. Scott. 2004. A novel sortase, SrtC2, from Streptococcus pyogenes anchors a surface protein containing a QVPTGV motif to the cell wall. J. Bacteriol. 186:5865-5875.
4. Bates, C. S., G. E. Montanez, C. R. Woods, R. M. Vincent, and Z. Eichenbaum. 2003. Identification and characterization of a Streptococcus pyogenes operon involved in binding of hemoproteins and acquisition of iron. Infect. Immun. 71:1042-1055.
5. Bates, C. S., C. Toukoki, M. N. Neely, and Z. Eichenbaum. 2005. Characterization of MtsR, a new metal regulator in group A streptococcus, involved in iron acquisition and virulence. Infect. Immun. 73:5743-5753.
6. Bisno, A. L., M. O. Brito, and C. M. Collins. 2003. Molecular basis of group A streptococcal virulence. Lancet Infect. Dis. 3:191-200.
7. Caswell, C. C., E. Lukomska, N. S. Seo, M. Hook, and S. Lukomski. 2007. Scl1-dependent internalization of group A streptococcus via direct interactions with the alpha2beta(1) integrin enhances pathogen survival and reemergence. Mol. Microbiol. 64:1319-1331.
8. Clarke, S. R., M. D. Wiltshire, and S. J. Foster. 2004. IsdA of Staphylococcus aureus is a broad spectrum, iron-regulated adhesin. Mol. Microbiol. 51:1509-1519.
9. Cunningham, M. W. 2000. Pathogenesis of group A streptococcal infections. Clin. Microbiol. Rev. 13:470-511.
10. Dinkla, K., M. Rohde, W. T. Jansen, E. L. Kaplan, G. S. Chhatwal, and S. R. Talay. 2003. Rheumatic fever-associated Streptococcus pyogenes isolates aggregate collagen. J. Clin. Investig. 111:1905-1912.
11. Dryla, A., B. Hoffmann, D. Gelbmann, C. Giefing, M. Hanner, A. Meinke, A. S. Anderson, W. Koppensteiner, R. Konrat, A. von Gabain, and E. Nagy. 2007. High-affinity binding of the staphylococcal HarA protein to haptoglobin and hemoglobin involves a domain with an antiparallel eight-stranded β-barrel fold. J. Bacteriol. 189:254-264.
12. Eichenbaum, Z., M. J. Federle, D. Marra, W. M. de Vos, O. P. Kuipers, M. Kleerebezem, and J. R. Scott. 1998. Use of the lactococcal nisA promoter to regulate gene expression in gram-positive bacteria: comparison of induction level and promoter strength. Appl. Environ. Microbiol. 64:2763-2769.
13. Eichenbaum, Z., E. Muller, S. A. Morse, and J. R. Scott. 1996. Acquisition of iron from host proteins by the group A streptococcus. Infect. Immun. 64:5428-5429.
14. Elsner, A., B. Kreikemeyer, A. Braun-Kiewnick, B. Spellerberg, B. A. Buttaro, and A. Podbielski. 2002. Involvement of Lsp, a member of the LraI-lipoprotein family in Streptococcus pyogenes, in eukaryotic cell adhesion and internalization. Infect. Immun. 70:4859-4869.
15. Fischetti, V. A., K. F. Jones, and J. R. Scott. 1985. Size variation of the M protein in group A streptococci. J. Exp. Med. 161:1384-1401.
16. Francis, R. T., Jr., J. W. Booth, and R. R. Becker. 1985. Uptake of iron from hemoglobin and the haptoglobin-hemoglobin complex by hemolytic bacteria. Int. J. Biochem. 17:767-773.
17. Giannakis, E., T. S. Jokiranta, R. J. Ormsby, T. G. Duthy, D. A. Male, D. Christiansen, V. A. Fischetti, C. Bagley, B. E. Loveland, and D. L. Gordon. 2002. Identification of the streptococcalMprotein binding site on membrane cofactor protein (CD46). J. Immunol. 168:4585-4592.
18. Glantz, S. A. 2005. Primer of biostatistics, 6th ed. McGraw-Hill Medical Publications, New York, NY.
19. Grigg, J. C., C. L. Vermeiren, D. E. Heinrichs, and M. E. Murphy. 2007. Haem recognition by a Staphylococcus aureus NEAT domain. Mol. Microbiol. 63:139-149.
20. Kobe, B., and A. V. Kajava. 2001. The leucine-rich repeat as a protein recognition motif. Curr. Opin. Struct. Biol. 11:725-732.
21. Kocks, C., E. Gouin, M. Tabouret, P. Berche, H. Ohayon, and P. Cossart. 1992. L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein. Cell 68:521-531.
22. Kreikemeyer, B., M. Klenk, and A. Podbielski. 2004. The intracellular status of Streptococcus pyogenes: role of extracellular matrix-binding proteins and their regulation. Int. J. Med. Microbiol. 294:177-188.
23. Kreikemeyer, B., K. S. McIver, and A. Podbielski. 2003. Virulence factor regulation and regulatory networks in Streptococcus pyogenes and their impact on pathogen-host interactions. Trends Microbiol. 11:224-232.
24. Kreikemeyer, B., M. Nakata, S. Oehmcke, C. Gschwendtner, J. Normann, and A. Podbielski. 2005. Streptococcus pyogenes collagen type I-binding Cpa surface protein. Expression profile, binding characteristics, biological functions, and potential clinical impact. J. Biol. Chem. 280:33228-33239.
25. Lecuit, M., H. Ohayon, L. Braun, J. Mengaud, and P. Cossart. 1997. Internalin of Listeria monocytogenes with an intact leucine-rich repeat region is sufficient to promote internalization. Infect. Immun. 65:5309-5319.
26. Lei, B., L. M. Smoot, H. M. Menning, J. M. Voyich, S. V. Kala, F. R. Deleo, S. D. Reid, and J. M. Musser. 2002. Identification and characterization of a novel heme-associated cell surface protein made by Streptococcus pyogenes. Infect. Immun. 70:4494-4500.
27. Liu, M., and B. Lei. 2005. Heme transfer from streptococcal cell surface protein Shp to HtsA of transporter HtsABC. Infect. Immun. 73:5086-5092.
28. Manetti, A. G., C. Zingaretti, F. Falugi, S. Capo, M. Bombaci, F. Bagnoli, G. Gambellini, G. Bensi, M. Mora, A. M. Edwards, J. M. Musser, E. A. Graviss, J. L. Telford, G. Grandi, and I. Margarit. 2007. Streptococcus pyogenes pili promote pharyngeal cell adhesion and biofilm formation. Mol. Microbiol. 64:968-983.
29. Maresso, A. W., T. J. Chapa, and O. Schneewind. 2006. Surface protein IsdC and sortase B are required for heme-iron scavenging of Bacillus anthracis. J. Bacteriol. 188:8145-8152.
30. Maresso, A. W., and O. Schneewind. 2006. Iron acquisition and transport in Staphylococcus aureus. Biometals 19:193-203.
31. Marraffini, L. A., A. C. Dedent, and O. Schneewind. 2006. Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria. Microbiol. Mol. Biol. Rev. 70:192-221.
32. Mazmanian, S. K., E. P. Skaar, A. H. Gaspar, M. Humayun, P. Gornicki, J. Jelenska, A. Joachmiak, D. M. Missiakas, and O. Schneewind. 2003. Passage of heme-iron across the envelope of Staphylococcus aureus. Science 299:906-909.
33. Montanez, G. E., M. N. Neely, and Z. Eichenbaum. 2005. The streptococcal iron uptake (Siu) transporter is required for iron uptake and virulence in a zebrafish infection model. Microbiology 151:3749-3757.
34. Neely, M. N., J. D. Pfeifer, and M. Caparon. 2002. Streptococcus-zebrafish model of bacterial pathogenesis. Infect. Immun. 70:3904-3914.
35. Newton, S. M., P. E. Klebba, C. Raynaud, Y. Shao, X. Jiang, I. Dubail, C. Archer, C. Frehel, and A. Charbit. 2005. The svpA-srtB locus of Listeria monocytogenes: fur-mediated iron regulation and effect on virulence. Mol. Microbiol. 55:927-940.
36. Nygaard, T. K., G. C. Blouin, M. Liu, M. Fukumura, J. S. Olson, M. Fabian, D. M. Dooley, and B. Lei. 2006. The mechanism of direct heme transfer from the streptococcal cell surface protein Shp to HtsA of the HtsABC transporter. J. Biol. Chem. 281:20761-20771.
37. Okada, N., M. K. Liszewski, J. P. Atkinson, and M. Caparon. 1995. Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus. Proc. Natl. Acad. Sci. USA 92:2489-2493.
38. Pancholi, V., and V. A. Fischetti. 1992. A major surface protein on group A streptococci is a glyceraldehyde-3-phosphate-dehydrogenase with multiple binding activity. J. Exp. Med. 176:415-426.
39. Patti, J. M., B. L. Allen, M. J. McGavin, and M. Hook. 1994. MSCRAMM-mediated adherence of microorganisms to host tissues. Annu. Rev. Microbiol. 48:585-617.
40. Podbielski, A., M. Woischnik, B. Kreikemeyer, K. Bettenbrock, and B. A. Buttaro. 1999. Cysteine protease SpeB expression in group A streptococci is influenced by the nutritional environment but SpeB does not contribute to obtaining essential nutrients. Med. Microbiol. Immunol. (Berlin) 188:99-109.
41. Sambrook, J., T. Maniatis, and E. F. Fritsch. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
42. Schrager, H. M., S. Alberti, C. Cywes, G. J. Dougherty, and M. R. Wessels. 1998. Hyaluronic acid capsule modulates M protein-mediated adherence and acts as a ligand for attachment of group A streptococcus to CD44 on human keratinocytes. J. Clin. Investig. 101:1708-1716.
43. Schrager, H. M., J. G. Rheinwald, and M. R. Wessels. 1996. Hyaluronic acid capsule and the role of streptococcal entry into keratinocytes in invasive skin infection. J. Clin. Investig. 98:1954-1958.
44. Schwarz-Linek, U., M. Hook, and J. R. Potts. 2006. Fibronectin-binding proteins of gram-positive cocci. Microbes Infect. 8:2291-2298.
45. Scott, J. R., and T. C. Barnett. 2006. Surface proteins of gram-positive bacteria and how they get there. Annu. Rev. Microbiol. 60:397-423.
46. Scott, J. R., P. C. Guenthner, L. M. Malone, and V. A. Fischetti. 1986. Conversion of an M-group A streptococcus to M+ by transfer of a plasmid containing an M6 gene. J. Exp. Med. 164:1641-1651.
47. Simon, D., and J. J. Ferretti. 1991. Electrotransformation of Streptococcus pyogenes with plasmid and linear DNA. FEMS Microbiol. Lett. 66:219-224.
48. Snider, L. A., and S. E. Swedo. 2003. Post-streptococcal autoimmune disorders of the central nervous system. Curr. Opin. Neurol. 16:359-365.
49. Sumby, P., S. F. Porcella, A. G. Madrigal, K. D. Barbian, K. Virtaneva, S. M. Ricklefs, D. E. Sturdevant, M. R. Graham, J. Vuopio-Varkila, N. P. Hoe, and J. M. Musser. 2005. Evolutionary origin and emergence of a highly successful clone of serotype M1 group A streptococcus involved multiple horizontal gene transfer events. J. Infect. Dis. 192:771-782.
50. Talay, S. R. 2005. Gram-positive adhesins. Contrib. Microbiol. 12:90-113.
51. Taylor, J. M., and D. E. Heinrichs. 2002. Transferrin binding in Staphylococcus aureus: involvement of a cell wall-anchored protein. Mol. Microbiol. 43:1603-1614.
52. Terao, Y., S. Kawabata, E. Kunitomo, I. Nakagawa, and S. Hamada. 2002. Novel laminin-binding protein of Streptococcus pyogenes, Lbp, is involved in adhesion to epithelial cells. Infect. Immun. 70:993-997.
53. Torres, V. J., G. Pishchany, M. Humayun, O. Schneewind, and E. P. Skaar. 2006. Staphylococcus aureus IsdB is a hemoglobin receptor required for heme-iron utilization. J. Bacteriol. 188:8421-8429.
54. Westerfield, M. 1995. The zebrafish book: guide for the laboratory use zebrafish (Danio rerio), 3rd ed. University of Oregon Press, Eugene.