메뉴 건너뛰기




Volumn 31, Issue 49, 2012, Pages 5073-5080

Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation

Author keywords

breast cancer; estrogen; mTOR; rapamycin; S6K1

Indexed keywords

40 S RIBOSOMAL S6 KINASE 1; ESTROGEN RECEPTOR ALPHA; RIBOSOME PROTEIN; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

EID: 84870823381     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.657     Document Type: Article
Times cited : (59)

References (35)
  • 1
    • 77952007543 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR): Conducting thecellular signaling symphony
    • Foster KG, Fingar DC. Mammalian target of rapamycin (mTOR): conducting thecellular signaling symphony. J Biol Chem 2010; 285: 14071-14077.
    • (2010) J Biol Chem , vol.285 , pp. 14071-14077
    • Foster, K.G.1    Fingar, D.C.2
  • 2
    • 78650239404 scopus 로고    scopus 로고
    • Functions and regulation of the 70kDa ribosomal S6 kinases
    • Fenton TR, Gout IT. Functions and regulation of the 70kDa ribosomal S6 kinases.Int J Biochem Cell Biol 2011; 43: 47-59.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 47-59
    • Fenton, T.R.1    Gout, I.T.2
  • 3
    • 67349217986 scopus 로고    scopus 로고
    • Molecular mechanisms of mTOR-mediated translational control
    • Ma XM, Blenis J. Molecular mechanisms of mTOR-mediated translational control.Nat Rev Mol Cell Biol 2009; 10: 307-318.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 307-318
    • Ma, X.M.1    Blenis, J.2
  • 4
    • 0026659046 scopus 로고
    • Rapamycin-FKBP specifically blocksgrowth-dependent activation of and signaling by the 70 kd S6 protein kinases
    • Chung J, Kuo CJ, Crabtree GR, Blenis J. Rapamycin-FKBP specifically blocksgrowth-dependent activation of and signaling by the 70 kd S6 protein kinases.Cell 1992; 69: 1227-1236.
    • (1992) Cell , vol.69 , pp. 1227-1236
    • Chung, J.1    Kuo, C.J.2    Crabtree, G.R.3    Blenis, J.4
  • 5
    • 0032538890 scopus 로고    scopus 로고
    • Disruption of thep70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functionalS6 kinase
    • Shima H, Pende M, Chen Y, Fumagalli S, Thomas G, Kozma SC. Disruption of thep70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functionalS6 kinase. EMBO J 1998; 17: 6649-6659.
    • (1998) EMBO J , Issue.17 , pp. 6649-6659
    • Shima, H.1    Pende, M.2    Chen, Y.3    Fumagalli, S.4    Thomas, G.5    Kozma, S.C.6
  • 6
    • 0027336002 scopus 로고
    • P70s6k function is essential for G1progression
    • Lane HA, Fernandez A, Lamb NJ, Thomas G. p70s6k function is essential for G1progression. Nature 1993; 363: 170-172.
    • (1993) Nature , vol.363 , pp. 170-172
    • Lane, H.A.1    Fernandez, A.2    Lamb, N.J.3    Thomas, G.4
  • 7
    • 65249190250 scopus 로고    scopus 로고
    • S6 kinase 1regulates estrogen receptor alpha in control of breast cancer cell proliferation
    • Yamnik RL, Digilova A, Davis DC, Brodt ZN, Murphy CJ, Holz MK. S6 kinase 1regulates estrogen receptor alpha in control of breast cancer cell proliferation.J Biol Chem 2009; 284: 6361-6369.
    • (2009) J Biol Chem , vol.284 , pp. 6361-6369
    • Yamnik, R.L.1    Digilova, A.2    Davis, D.C.3    Brodt, Z.N.4    Murphy, C.J.5    Holz, M.K.6
  • 8
    • 34547574720 scopus 로고    scopus 로고
    • A new mutational AKTivation in the PI3K pathway
    • Brugge J, Hung MC, Mills GB. A new mutational AKTivation in the PI3K pathway.Cancer Cell 2007; 12: 104-107.
    • (2007) Cancer Cell , vol.12 , pp. 104-107
    • Brugge, J.1    Hung, M.C.2    Mills, G.B.3
  • 9
    • 0034596364 scopus 로고    scopus 로고
    • Detectingactivation of ribosomal protein S6 kinase by complementary DNA and tissuemicroarray analysis
    • Barlund M, Forozan F, Kononen J, Bubendorf L, Chen Y, Bittner ML et al. Detectingactivation of ribosomal protein S6 kinase by complementary DNA and tissuemicroarray analysis. J Natl Cancer Inst 2000; 92: 1252-1259.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1252-1259
    • Barlund, M.1    Forozan, F.2    Kononen, J.3    Bubendorf, L.4    Chen, Y.5    Bittner, M.L.6
  • 10
    • 14344280240 scopus 로고    scopus 로고
    • Comprehensive copy number and gene expression profiling of the 17q23amplicon in human breast cancer
    • Monni O, Barlund M, Mousses S, Kononen J, Sauter G, Heiskanen M et al.Comprehensive copy number and gene expression profiling of the 17q23amplicon in human breast cancer. Proc Natl Acad Sci USA 2001; 98: 5711-5716.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5711-5716
    • Monni, O.1    Barlund, M.2    Mousses, S.3    Kononen, J.4    Sauter, G.5    Heiskanen, M.6
  • 11
    • 0033119602 scopus 로고    scopus 로고
    • Localization of PS6K tochromosomal region 17q23 and determination of its amplification in breastcancer
    • Couch FJ, Wang XY, Wu GJ, Qian J, Jenkins RB, James CD. Localization of PS6K tochromosomal region 17q23 and determination of its amplification in breastcancer. Cancer Res 1999; 59: 1408-1411.
    • (1999) Cancer Res , vol.59 , pp. 1408-1411
    • Couch, F.J.1    Wang, X.Y.2    Wu, G.J.3    Qian, J.4    Jenkins, R.B.5    James, C.D.6
  • 13
    • 65549165975 scopus 로고    scopus 로고
    • Genetic alterationsand oncogenic pathways associated with breast cancer subtypes
    • Hu X, Stern HM, Ge L, O'Brien C, Haydu L, Honchell CD et al. Genetic alterationsand oncogenic pathways associated with breast cancer subtypes. Mol Cancer Res2009; 7: 511-522.
    • (2009) Mol Cancer Res , vol.7 , pp. 511-522
    • Hu, X.1    Stern, H.M.2    Ge, L.3    O'Brien, C.4    Haydu, L.5    Honchell, C.D.6
  • 14
    • 2442534048 scopus 로고    scopus 로고
    • Overexpression of P70 S6 kinase protein is associatedwith increased risk of locoregional recurrence in node-negative premenopausalearly breast cancer patients
    • van der Hage JA, van den Broek LJ, Legrand C, Clahsen PC, Bosch CJ,Robanus-Maandag EC et al. Overexpression of P70 S6 kinase protein is associatedwith increased risk of locoregional recurrence in node-negative premenopausalearly breast cancer patients. Br J Cancer 2004; 90: 1543-1550.
    • (2004) Br J Cancer , vol.90 , pp. 1543-1550
    • Van Der Hage, J.A.1    Van Den Broek, L.J.2    Legrand, C.3    Clahsen, P.C.4    Bosch, C.J.5    Robanus-Maandag, E.C.6
  • 15
    • 0026557343 scopus 로고
    • Systemic treatment of earlybreast cancer by hormonal Cytotoxic or immune therapy 133 randomised trialsinvolving 31,000 recurrences and 24,000 deaths among 75,000 women
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group. Systemic treatment of earlybreast cancer by hormonal Cytotoxic or immune therapy 133 randomised trialsinvolving 31,000 recurrences and 24,000 deaths among 75,000 women. Lancet1992; 339: 1-15.
    • (1992) Lancet , vol.339 , pp. 1-15
  • 16
    • 2942565669 scopus 로고    scopus 로고
    • Overcoming endocrine therapy resistance by signal transductioninhibition
    • Ellis M. Overcoming endocrine therapy resistance by signal transductioninhibition. Oncologist 2004; 9(Suppl 3): 20-26.
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 3 , pp. 20-26
    • Ellis, M.1
  • 17
    • 33646546654 scopus 로고    scopus 로고
    • Genomic alterationsidentified by array comparative genomic hybridization as prognostic markers intamoxifen-treated estrogen receptor-positive breast cancer
    • Han W, Han MR, Kang JJ, Bae JY, Lee JH, Bae YJ et al. Genomic alterationsidentified by array comparative genomic hybridization as prognostic markers intamoxifen-treated estrogen receptor-positive breast cancer. BMC Cancer 2006;6: 92.
    • (2006) BMC Cancer , vol.6 , pp. 92
    • Han, W.1    Han, M.R.2    Kang, J.J.3    Bae, J.Y.4    Lee, J.H.5    Bae, Y.J.6
  • 18
    • 65949105732 scopus 로고    scopus 로고
    • Copy numberalterations that predict metastatic capability of human breast cancer
    • Zhang Y, Martens JW, Yu JX, Jiang J, Sieuwerts AM, Smid M et al. Copy numberalterations that predict metastatic capability of human breast cancer. Cancer Res2009; 69: 3795-3801.
    • (2009) Cancer Res , vol.69 , pp. 3795-3801
    • Zhang, Y.1    Martens, J.W.2    Yu, J.X.3    Jiang, J.4    Sieuwerts, A.M.5    Smid, M.6
  • 19
    • 71549166007 scopus 로고    scopus 로고
    • MTOR/S6K1 and MAPK/RSK signaling pathways coordinatelyregulate estrogen receptor alpha serine 167 phosphorylation
    • Yamnik RL, Holz MK. mTOR/S6K1 and MAPK/RSK signaling pathways coordinatelyregulate estrogen receptor alpha serine 167 phosphorylation. FEBS Lett 2010;584: 124-128.
    • (2010) FEBS Lett , vol.584 , pp. 124-128
    • Yamnik, R.L.1    Holz, M.K.2
  • 20
    • 79952135852 scopus 로고    scopus 로고
    • The IGF pathway regulates ERalphathrough A S6K1-dependent mechanism in breast cancer cells
    • Becker MA, Ibrahim YH, Cui X, Lee AV, Yee D. The IGF pathway regulates ERalphathrough a S6K1-dependent mechanism in breast cancer cells. Mol Endocrinol2011; 25: 516-528.
    • (2011) Mol Endocrinol , vol.25 , pp. 516-528
    • Becker, M.A.1    Ibrahim, Y.H.2    Cui, X.3    Lee, A.V.4    Yee, D.5
  • 21
    • 42149103735 scopus 로고    scopus 로고
    • Genomicanalysis of estrogen cascade reveals histone variant H2A.Z associated with breastcancer progression
    • Hua S, Kallen CB, Dhar R, Baquero MT, Mason CE, Russell BA et al. Genomicanalysis of estrogen cascade reveals histone variant H2A.Z associated with breastcancer progression. Mol Syst Biol 2008; 4: 188.
    • (2008) Mol Syst Biol , vol.4 , pp. 188
    • Hua, S.1    Kallen, C.B.2    Dhar, R.3    Baquero, M.T.4    Mason, C.E.5    Russell, B.A.6
  • 23
    • 0030832993 scopus 로고    scopus 로고
    • Effects of multipleestrogen responsive elements, their spacing, and location on estrogen responseof reporter genes
    • Sathya G, Li W, Klinge CM, Anolik JH, Hilf R, Bambara RA. Effects of multipleestrogen responsive elements, their spacing, and location on estrogen responseof reporter genes. Mol Endocrinol 1997; 11: 1994-2003.
    • (1997) Mol Endocrinol , vol.11 , pp. 1994-2003
    • Sathya, G.1    Li, W.2    Klinge, C.M.3    Anolik, J.H.4    Hilf, R.5    Bambara, R.A.6
  • 24
    • 34447130861 scopus 로고    scopus 로고
    • Positive crossregulatoryloop ties GATA-3 to estrogen receptor alpha expression in breastcancer
    • Eeckhoute J, Keeton EK, Lupien M, Krum SA, Carroll JS, Brown M. Positive crossregulatoryloop ties GATA-3 to estrogen receptor alpha expression in breastcancer. Cancer Res 2007; 67: 6477-6483.
    • (2007) Cancer Res , vol.67 , pp. 6477-6483
    • Eeckhoute, J.1    Keeton, E.K.2    Lupien, M.3    Krum, S.A.4    Carroll, J.S.5    Brown, M.6
  • 25
    • 78650185393 scopus 로고    scopus 로고
    • Estrogen-InducedAurora Kinase-A (AURKA) gene expression is activated by GATA-3 in estrogenreceptor-positive breast cancer cells
    • Jiang S, Katayama H, Wang J, Li S, Hong Y, Radvanyi L et al. Estrogen-InducedAurora Kinase-A (AURKA) gene expression is activated by GATA-3 in estrogenreceptor-positive breast cancer cells. Hormones Cancer 2010; 1: 11-20.
    • Hormones Cancer , vol.2010 , Issue.1 , pp. 11-20
    • Jiang, S.1    Katayama, H.2    Wang, J.3    Li, S.4    Hong, Y.5    Radvanyi, L.6
  • 27
    • 2442670465 scopus 로고    scopus 로고
    • About GATA3, HNF3A, and XBP1, three genes co-expressedwith the oestrogen receptor-alpha gene (ESR1) in breast cancer
    • Lacroix M, Leclercq G. About GATA3, HNF3A, and XBP1, three genes co-expressedwith the oestrogen receptor-alpha gene (ESR1) in breast cancer. Mol CellEndocrinol 2004; 219: 1-7.
    • (2004) Mol CellEndocrinol , vol.219 , pp. 1-7
    • Lacroix, M.1    Leclercq, G.2
  • 30
    • 57349173558 scopus 로고    scopus 로고
    • AKT alters genome-wide estrogen receptor alpha binding and impacts estrogensignaling in breast cancer
    • Bhat-Nakshatri P, Wang G, Appaiah H, Luktuke N, Carroll JS, Geistlinger TR et al.AKT alters genome-wide estrogen receptor alpha binding and impacts estrogensignaling in breast cancer. Mol Cell Biol 2008; 28: 7487-7503.
    • (2008) Mol Cell Biol , vol.28 , pp. 7487-7503
    • Bhat-Nakshatri, P.1    Wang, G.2    Appaiah, H.3    Luktuke, N.4    Carroll, J.S.5    Geistlinger, T.R.6
  • 31
  • 32
    • 15844388060 scopus 로고    scopus 로고
    • Estrogen receptors and their downstream targets in cancer
    • Ikeda K, Inoue S. Estrogen receptors and their downstream targets in cancer. ArchHistol Cytol 2004; 67: 435-442.
    • (2004) ArchHistol Cytol , vol.67 , pp. 435-442
    • Ikeda, K.1    Inoue, S.2
  • 33
    • 66849136781 scopus 로고    scopus 로고
    • Phase II randomized study of neoadjuvant everolimus plus letrozole comparedwith placebo plus letrozole in patients with estrogen receptor-positive breastcancer
    • Baselga J, Semiglazov V, van Dam P, Manikhas A, Bellet M, Mayordomo J et al.Phase II randomized study of neoadjuvant everolimus plus letrozole comparedwith placebo plus letrozole in patients with estrogen receptor-positive breastcancer. J Clin Oncol 2009; 27: 2630-2637.
    • (2009) J Clin Oncol , vol.27 , pp. 2630-2637
    • Baselga, J.1    Semiglazov, V.2    Van Dam, P.3    Manikhas, A.4    Bellet, M.5    Mayordomo, J.6
  • 34
    • 79960836840 scopus 로고    scopus 로고
    • Are we missing the mTOR target in breast cancer?
    • Johnston SR. Are we missing the mTOR target in breast cancer? Breast Cancer ResTreat 2011; 128: 607-611.
    • (2011) Breast Cancer ResTreat , vol.128 , pp. 607-611
    • Johnston, S.R.1
  • 35
    • 71749119589 scopus 로고    scopus 로고
    • Globalanalysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 andpoly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells
    • Frizzell KM, Gamble MJ, Berrocal JG, Zhang T, Krishnakumar R, Cen Y et al. Globalanalysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 andpoly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells. J Biol Chem2009; 284: 33926-33938.
    • (2009) J Biol Chem , vol.284 , pp. 33926-33938
    • Frizzell, K.M.1    Gamble, M.J.2    Berrocal, J.G.3    Zhang, T.4    Krishnakumar, R.5    Cen, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.