Effects of multiple estrogen responsive elements, their spacing, and location on estrogen response of reporter genes

Molecular Endocrinology

Volumn 11, Issue 13, 1997, Pages 1994-2003

  Sathya, G ^a   Li, Wenzhuo ^a   Klinge, Carolyn M ^b   Anolik, Jennifer H ^a   Hilf, Russell ^a   Bambara, Robert A ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN;

ARTICLE; CANCER CELL CULTURE; HORMONE RESPONSE; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SIMIAN VIRUS 40;

MINK CELL FOCUS-FORMING VIRUS; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0030832993     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.13.0039     Document Type: Article

References (44)

1. Beato M, Herrlich P, Schutz G 1995 Steroid hormone receptors: many actors in search of a plot. Cell 83:851-857
2. Tsai MJ, O'Malley BW 1994 Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 63:451-486
3. Evans RM 1988 The steroid and thyroid hormone receptor superfamily. Science 240:889-895
4. Klein-Hitpass L, Schorpp M, Wagner U, Ryffel GU 1986 An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells. Cell 46:1053-1061
5. Berry M, Nunez AM, Chambon P 1989 Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence. Proc Natl Acad Sci USA 86:1218-1222
6. Klein-Hitpass L, Ryffel GU, Heitlinger E, Cato AC 1988 A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor. Nucleic Acids Res 16:647-663
7. Peale Jr FV, Ludwig LB, Zain S, Hilf R, Bambara RA 1988 Properties of a high-affinity DNA binding site for estrogen receptor. Proc Natl Acad Sci USA 85:1038-1042
8. Kraus WL, Montano MM, Katzenellenbogen BS 1994 Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene. Mol Endocrinol 8:952-969
9. Martinez E, Givel F, Wahli W 1987 The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element. EMBO J 6:3719-27
10. Martinez E, Wahli W 1989 Cooperative binding of estrogen receptor to imperfect estrogen-responsive DNA elements correlates with their synergistic hormone-dependent enhancer activity. EMBO J 8:3781-3791
11. Ponglikitmongkol M, White JH, Chambon P 1990 Synergistic activation of transcription by the human estrogen receptor bound to tandem responsive elements. EMBO J 9:2221-2231
12. Kato S, Tora L, Yamauchi J, Masushige S, Bellard M, Chambon P 1992 A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically. Cell 68:731-742
13. Kato S, Sasaki H, Suzawa M, Masushige S, Tora L, Chambon P, Gronemeyer H 1995 Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors. Mol Cell Biol 15:5858-5867
14. Jordan VC 1995 Tamoxifen: toxicities and drug resistance during the treatment and prevention of breast cancer. Annu Rev Pharmacol Toxicol 35:195-211
15. Jordan VC 1995 Third annual William L. McGuire Memorial Lecture. "Studies on the estrogen receptor in breast cancer"-20 years as a target for the treatment and prevention of cancer. Breast Cancer Res Treat 36:267-285
16. Chang TC, Nardulli AM, Lew D, Shapiro DJ 1992 The role of estrogen response elements in expression of the Xenopus laevis vitellogenin B1 gene. Mol Endocrinol 6:346-354
17. Teng CT 1994 Lactoferrin gene promoter in human and mouse. Analogous and dissimilar characteristics. Adv Exp Med Biol 357:183-196
18. Burch JB, Evans MI, Friedman TM, O'Malley PJ 1988 Two functional estrogen response elements are located upstream of the major chicken vitellogenin gene. Mol Cell Biol 8:1123-1131
19. Klinge CM, Peale Jr FV, Hilf R, Bambara RA, Zain S 1992 Cooperative estrogen receptor interaction with consensus or variant estrogen responsive elements in vitro. Cancer Res 52:1073-1081
20. Gill RK, Christakos S 1995 Regulation by estrogen through the 5′-flanking region of the mouse calbindin-D28k gene. Mol Endocrinol 9:319-326
21. Rishi AK, Shao ZM, Baumann RG, Li XS, Sheikh MS, Kimura S, Bashirelahi N, Fontana JA 1995 Estradiol regulation of the human retinoic acid receptor alpha gene in human breast carcinoma cells is mediated via an imperfect half-palindromic estrogen response element and Sp1 motifs. Cancer Res 55:4999-5006
22. Liu D, Xiong F, Hew CL 1995 Functional analysis of estrogen-responsive elements in chinook salmon (Oncorhynchus tschawytscha) gonadotropin II beta subunit gene. Endocrinology 136:3486-3493
23. May FE, Smith DJ, Westley BR 1993 The human cathepsin D-encoding gene is transcribed from an estrogen-regulated and a constitutive start point. Gene 134: 277-282
24. Ptashne M 1988 How eukaryotic transcriptional activators work. Nature 335:683-689
25. Nardulli AM, Grobner C, Cotter D 1995 Estrogen receptor-induced DNA bending: orientation of the bend and replacement of an estrogen response element with an intrinsic DNA bending sequence. Mol Endocrinol 9:1064-1076
26. Nardulli AM, Lew D, Erijman L, Shapiro DJ 1991 Purified estrogen receptor DNA binding domain expressed in Escherichia coli activates transcription of an estrogen-responsive promoter in cultured cells. J Biol Chem 266:24070-24076
27. Nardulli AM, Shapiro DJ 1992 Binding of the estrogen receptor DNA-binding domain to the estrogen response element induces DNA bending. Mol Cell Biol 12: 2037-2042
28. Nardulli AM, Greene GL, Shapiro DJ 1993 Human estrogen receptor bound to an estrogen response element bends DNA. Mol Endocrinol 7:331-340
29. Nardulli AM, Shapiro DJ 1993 DNA bending by nuclear receptors. Receptor 3:247-255
30. Nardulli AM, Romine LE, Carpo C, Greene GL, Rainish B 1996 Estrogen receptor affinity and location of consensus and imperfect estrogen response elements influence transcription activation of simplified promoters. Mol Endocrinol 10:694-704
31. Potthoff SJ, Romine LE, Nardulli AM 1996 Effects of wild type and mutant estrogen receptors on DNA flexibility, DNA bending, and transcription activation. Mol Endocrinol 10:1095-1106
32. Burch JB, Fischer AH 1990 Chromatin studies reveal that an ERE is located far upstream of a vitellogenin gene and that a distal tissue-specific hypersensitive site is conserved for two coordinately regulated vitellogenin genes. Nucleic Acids Res 18:4157-4165
33. Renner K, Sock E, Bermingham Jr JR, Wegner M 1996 Expression of the gene for the POU domain transcription factor Tst-1/Oct6 is regulated by an estrogen-dependent enhancer. Nucleic Acids Res 24:4552-4557
34. Tora L, Gaub MP, Mader S, Dierich A, Bellard M, Chambon P 1988 Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter. EMBO J 7:3771-3778
35. Augereau P, Miralles F, Cavailles V, Gaudelet C, Parker M, Rochefort H 1994 Characterization of the proximal estrogen-responsive element of human cathepsin D gene. Mol Endocrinol 8:693-703
36. Slater EP, Redeuilh G, Beato M 1991 Hormonal regulation of vitellogenin genes: an estrogen-responsive element in the Xenopus A2 gene and a multihormonal regulatory region in the chicken II gene. Mol Endocrinol 5:386-396
37. Richard S, Zingg HH 1990 The human oxytocin gene promoter is regulated by estrogens. J Biol Chem 265:6098-6103
38. Anolik JH, Klinge CM, Bambara RA, Hilf R 1993 Differential impact of flanking sequences on estradiol-vs. 4-hydroxytamoxifen-liganded estrogen receptor binding to estrogen responsive element DNA. J Steroid Biochem Mol Biol 46:713-730
39. Anolik JH, Klinge CM, Hilf R, Bambara RA 1995 Cooperative binding of estrogen receptor to DNA depends on spacing of binding sites, flanking sequence, and ligand. Biochemistry 34:2511-2520
40. Anolik JH, Klinge CM, Brolly CL, Bambara RA, Hilf R 1996 Stability of the ligand-estrogen receptor interaction depends on estrogen response element flanking sequences and cellular factors. J Steroid Biochem Mol Biol 59:413-429
41. Klinge CM, Bambara RA, Hilf R 1992 Antiestrogen-liganded estrogen receptor interaction with estrogen responsive element DNA in vitro. J Steroid Biochem Mol Biol 43:249-262
42. Klinge CM, Bambara RA, Hilf R 1992 What differentiates antiestrogen-liganded vs. estradiol-liganded estrogen receptor action? [published erratum appears in Oncol Res 1992;4(6):255]. Oncol Res 4:137-144
43. Klinge CM, Traish AM, Bambara RA, Hilf R 1996 Dissociation of 4-hydroxytamoxifen, but not estradiol or tamoxifen aziridine, from the estrogen receptor as the receptor binds estrogen response element DNA. J Steroid Biochem Mol Biol 57:51-66
44. Campbell MJ 1995 Lipofection reagents prepared by a simple ethanol injection technique. Biotechniques 18: 1027-32