PMA-induced dissociation of Ku86 from the promoter causes transcriptional up-regulation of histamine H 1 receptor

Scientific Reports

Volumn 2, Issue , 2012, Pages

  Mizuguchi, Hiroyuki ^a   Miyagi, Kohei ^a   Terao, Takuma ^a   Sakamoto, Noriko ^a   Yamawaki, Yosuke ^a,b   Adachi, Tsubasa ^a   Ono, Shohei ^a   Sasaki, Yohei ^a   Yoshimura, Yoshiyuki ^a,c   Kitamura, Yoshiaki ^a   Takeda, Noriaki ^a   Fukui, Hiroyuki ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b HIROSHIMA INTERNATIONAL UNIVERSITY   (Japan)

^c TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; HISTAMINE H1 RECEPTOR; KU ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C DELTA; TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; BINDING SITE; CELL LINE; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENE EXPRESSION REGULATION; GENE ORDER; GENETIC TRANSCRIPTION; GENETICS; HUMAN; MALE; METABOLISM; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN BINDING; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; ANTIGENS, NUCLEAR; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA-BINDING PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GENE ORDER; HUMANS; MALE; POLY(ADP-RIBOSE) POLYMERASES; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN KINASE C-DELTA; RATS; RECEPTORS, HISTAMINE H1; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84870807969     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00916     Document Type: Article

References (52)

1. O'Mahony, L., Akdis, M. & Akdis, C. Regulation of the immune response and inflammation by histamine and histamine receptors. J Allergy Clin Immunol. 128, 1153-1162 (2011).
2. Hamano, N. et al. Expression of histamine receptors in nasal epithelial cells and endothelial cells: the effects of sex hormones. Int. Arch. Allergy Immunol. 115, 220-227 (1998). (Pubitemid 28105450)
3. Nakasaki, T. et al. Effect of PAF on histamineH1 receptormRNAexpression in rat trigeminal ganglia. Prostaglandins Other Lipid Mediat. 58, 29-41 (1999). (Pubitemid 30398541)
4. Dinh, Q. T. et al. Transcriptional up-regulation of histamine receptor-1 in epithelial, mucus and inflammatory cells in perennial allergic rhinitis. Clin. Exp. Allergy 35, 1443-1448 (2005).
5. Iriyoshi, N., Takeuchi, K., Yuta, A., Ukai, K. & Sakakura, Y. Increased expression of H1R mRNA in allergic rhinitis. Clin. Exp. Allergy 26, 379-385 (1996).
6. Shimada, H. The factor of hypersensitivity of the human nasal mucosa: receptor binding assay of histamine H1 receptors. J. Jpn. Rhinol. Soc. 29, 225-233 (1990).
7. Abe, Y. et al. Effects of capsaicin desensitization on nasal allergy-like symptoms and histamine release in the nose induced by toluene diisocyanate in guinea pigs. Acta Otolaryngol. 112, 703-709 (1992).
8. Abe, Y. et al. Histamine content, synthesis and degradation in nasal mucosa and lung of guinea-pigs treated with toluene diisocyanate (TDI). Clin. Exp. Allergy 23, 512-517 (1993). (Pubitemid 23198233)
9. Kitamura, Y. et al. Effect of glucocorticoid on upregulation of histamine H1 receptor mRNA in nasal mucosa of rats sensitized by exposure to toluene diisocyanate. Acta Otolaryngol. 124, 1053-1058 (2004). (Pubitemid 39524751)
10. Murata, Y., Miyoshi, A., Kitamura, Y., Takeda, N. & Fukui, H. Up-regulation of H1Rs in an allergic rat nasal mucosa model. Inflamm. Res. 53, 11-12 (2004).
11. Mizuguchi, H. et al. Repeated pre-treatment with antihistamines sup-presses transcriptional up-regulations of histamine H1 receptor and interleukin-4 genes in toluene-2, 4-diisocyanate-sensitized rats. J. Pharmacol. Sci. 108, 480-486 (2008).
12. Mizuguchi, H. et al. Preseasonal prophylactic treatment with antihistamines suppresses nasal symptoms and expression of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis. Methods Find. Exp. Clin. Pharmacol. 32, 745-748 (2010).
13. Matsushita, C. et al. Identification of epigallocatechin-3-O-gallate as an active constituent in tea extract that suppresses transcriptional up-regulations of the histamine H1 receptor and interleukin-4 genes. J. Trad. Med. 25, 133-142 (2008).
14. Dev, S. et al. Suppression of histamine signaling by probiotic Lac-B: a possible mechanism of its anti-allergic effect. J. Pharmacol. Sci. 107, 159-166 (2008). (Pubitemid 351931016)
15. Dev, S. et al. Kujin suppresses histamine signaling at the transcriptional level in toluene 2, 4-diisocyanate-sensitized rats. J. Pharmacol. Sci. 109, 606-617 (2009).
16. Das, A. K. et al. Sho-seiryu-to suppresses histamine signaling at transcriptional level in TDI-sensitized nasal allergy model rats. Allergol. Int. 58, 81-88 (2009).
17. Shahriar, M. et al. Suplatast tosilate inhibits histamine signaling by direct and indirect down-regulation of histamine H1 receptor gene expression through suppression of histidine decarboxylase and IL-4 gene transcriptions. J. Immunol. 183, 2133-2141 (2009).
18. Ohuchi, Y. et al. Histamine-induced calcium mobilization in single cultured cells expressing histamine H1 receptors: a relationship between its sensitivity and the density of H1 receptors. Int. J. Mol. Med. 1, 355-360 (1998).
19. Das, A. K. et al. Stimulation of histamine H1 receptor up-regulates histamine receptor itself through activation of receptor gene transcription. J. Pharmacol. Sci. 103, 374-382 (2007). (Pubitemid 46640690)
20. Mizuguchi, H. et al. Involvement of PKCd/Extracellular signal-regulated kinase/Poly(ADP-ribose) polymerase-1 (PARP-1) signaling pathway in histamineinduced up-regulation of histamine H1 receptor gene expression in HeLa cells. J. Biol. Chem. 286, 30542-30551 (2011).
21. Lienard, P. et al. Regulation of the alpha-fetoprotein promoter: Ku binding and DNA spatial conformation. Biochimie 88, 1409-1417 (2006). (Pubitemid 44755223)
22. Bakker, R. A., Wieland, K., Timmerman, H. & Leurs, R. Constitutive activity of the histamine H(1) receptor reveals inverse agonism of histamine H(1) receptor antagonists. Eur. J. Pharmacol. 387, R5-R7 (2000). (Pubitemid 30035384)
23. Bakker, R. A., Schoonus, S. B., Smit, M. J., Timmerman, H. & Leurs, R. Histamine H(1)-receptor activation of nuclear factor-kappa B: roles for G beta gamma-and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling. Mol. Pharmacol. 60, 1133-1142 (2001). (Pubitemid 33027449)
24. Li, B., Navarro, S., Kasahara, N. & Comai, L. Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1. J. Biol. Chem. 279, 13659-13667 (2004). (Pubitemid 38468894)
25. Ren, J. & Guo, W. ERK1/2 regulate exocytosis through direct phosphorylation of the exocyst component Exo70. Dev. Cell 22, 967-978 (2012).
26. Lim, J. H., Liu, Y., Reineke, E. & Kao, H. Y. Mitogen-activated protein kinase extracellular signal-regulated kinase 2 phosphorylates and promotes Pin1 protein-dependent promyelocytic leukemia protein turnover. J. Biol. Chem. 286, 44403-44411 (2011).
27. Terada, N. et al. Diesel exhaust particulates upregulate histamine receptor mRNA and increase histamine-induced IL-8 and GM-CSF production in nasal epithelial cells and endothelial cells. Clin. Exp. Allergy 29, 52-59 (1999). (Pubitemid 29067652)
28. Matsubara, M., Ohmori, K. & Hasegawa, K. Histamine H1 receptor-stimulated interleukin 8 and granulocyte macrophage colony-stimulating factor production by bronchial epithelial cells requires extracellular signal-regulated kinase signaling via protein kinase C. Int. Arch. Allergy Immunol. 139, 279-293 (2006).
29. Masaki, T. et al. A nuclear factor-kB signaling pathway via protein kinase C d regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells. Mol. Biol. Cell. 22, 2144-2156 (2011).
30. Zhu, J. & Aurellian, L. AP-1 cis-response elements are involved in basal expression and Vmw110 transactivation of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10). Virology 231, 301-312 (1997). (Pubitemid 27244196)
31. Schaefer, M. et al. The transcription factors AP-1 and Ets are regulators of C3a receptor expression. J. Biol. Chem. 282, 42113-42123 (2005). (Pubitemid 43023180)
32. Mimori, T. et al. Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositisscleroderma overlap. J. Clin. Invest. 68, 611-620 (1981). (Pubitemid 11005035)
33. Gottlieb, T. M. & Jackson, S. P. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72, 131-142 (1993). (Pubitemid 23029700)
34. Lees-Miller, S. P., Chen, Y. R. & Anderson, C. W. Human cells contain a DNAactivated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol. Biol. Chem. 10, 6472-6481 (1990). (Pubitemid 120004591)
35. Ludwig, D. L. et al. Ku80 gene expression is Sp1-dependent and sensitive to CpG methylation within a novel cis element. Gene 199, 181-194 (1997). (Pubitemid 27448217)
36. Carter, T. H., Kopman, C. R. & James, C. B. DNA-stimulated protein phosphorylation in HeLa whole cell and nuclear extracts. Biochem. Biophys. Res. Commun. 157, 535-540 (1998).
37. Warriar, N., Pagé, N. & Govindan, M. V. Expression of human glucocorticoid receptor gene and interaction of nuclear proteins with the transcriptional control element. J. Biol. Chem. 271, 18662-18671 (1996). (Pubitemid 26322732)
38. Willis, D. M. et al. Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex. J. Biol. Chem. 277, 37280-37291 (2002).
39. D'Amours, D., Desnoyers, S., D'Silva, I. & Poirier, G. G. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J. 342, 249-268 (1999). (Pubitemid 29425344)
40. Oei, S. L. et al. Interaction of the transcription factor YY1 with human poly(ADPribosyl) transferase. Biochem. Biophys. Res. Commun. 240, 108-111 (1997). (Pubitemid 27503757)
41. Rawling, J. M. & Alvarez-Gonzalez R. TFIIF, a basal eukaryotic transcription factor, is a substrate for poly(ADP-ribosyl)ation. Biochem. J. 324, 249-253 (1997). (Pubitemid 27229390)
42. Nie, J. et al. Interaction of Oct-1 and automodification domain of poly(ADPribose) synthetase. FEBS Lett. 424, 27-32 (1998). (Pubitemid 28130345)
43. Kannan, P., Yu, Y., Wankhade, S. & Tainsky, M. A. PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation. Nucleic Acids Res. 27, 866-874 (1999). (Pubitemid 29209377)
44. Anderson, M. G., Scoggin, K. E., Simbulan-Rosenthal, C. M. & Steadman, J. A. Identification of poly(ADP-ribose) polymerase as a transcriptional coactivator of the human T-cell leukemia virus type 1 Tax protein. J. Virol. 74, 2169-2177 (2000). (Pubitemid 30091470)
45. Cervellera, M. N. & Sala, A. Poly(ADP-ribose) polymerase is a B-MYB coactivator. J. Biol. Chem. 275, 10692-10696 (2000).
46. Hassa, P. O. & Hottiger, M. O. The functional role of poly(ADPribose) polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders. Cell. Mol. Life Sci. 59, 1534-1553 (2002). (Pubitemid 35239308)
47. Gagne, J. P. et al. Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress. Nucleic Acid Res. 40, 7788-7805 (2012).
48. Kraus, W. L. & Lis, J. T. PARP goes transcription. Cell 113, 677-683 (2003). (Pubitemid 36724932)
49. Kim, M. Y., Mauro, S., Gevry, N., Lis, J. T. & Kraus, W. L. NAD1-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. Cell 119, 803-814 (2004). (Pubitemid 40017687)
50. Cohen-Armon, M. et al. DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. Mol. Cell 25, 297-308 (2007). (Pubitemid 46127778)
51. Kitamura, Y. et al. Preseasonal prophylactic treatment with antihistamines suppresses IL-5 but not IL-33 mRNA expression in the nasal mucosa of patients with seasonal allergic rhinitis caused by Japanese cedar pollen. Acta Oto-Laryngologica. 132, 434-438 (2012).
52. Yoshimura, Y. et al. Identification of protein substrates of Ca(21)/calmodulindependent protein kinase II in the postsynaptic density by protein sequencing and mass spectrometry. Biochem. Biophys. Res. Commun. 290, 948-954 (2002). (Pubitemid 34687453)