Coronary artery calcium for the prediction of mortality in young adults <45 years old and elderly adults >75 years old

European Heart Journal

Volumn 33, Issue 23, 2012, Pages 2955-2962

  Tota Maharaj, Rajesh ^a,b   Blaha, Michael J ^a   McEvoy, John W ^a   Blumenthal, Roger S ^a   Muse, Evan D ^a   Budoff, Matthew J ^c   Shaw, Leslee J ^d   Berman, Daniel S ^e   Rana, Jamal S ^e   Rumberger, John ^f   Callister, Tracy ^g   Rivera, Juan ^h   Agatston, Arthur ^h   Nasir, Khurram ⁱ  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b GREATER BALTIMORE MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CEDARS SINAI MEDICAL CENTER   (United States)

^f Princeton Longevity Center   (United States)

^g Tennessee Heart and Vascular Center   (United States)

^h Baptist Health System South Florida   (United States)

ⁱ Baptist Health System South Florida   (United States)

Author keywords

Ageing; Coronary artery calcium; Coronary CT; Coronary heart disease

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CARDIOVASCULAR RISK; CORONARY ARTERY CALCIUM SCORING; DIABETES MELLITUS; DYSLIPIDEMIA; FAMILY HISTORY; FEMALE; FOLLOW UP; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RISK ASSESSMENT; SCORING SYSTEM; SEX DIFFERENCE; SMOKING; SURVIVAL RATE;

ADULT; AGE FACTORS; AGED; CORONARY ARTERY DISEASE; EPIDEMIOLOGIC METHODS; FEMALE; HUMANS; MALE; MIDDLE AGED; VASCULAR CALCIFICATION; YOUNG ADULT;

EID: 84870794013     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehs230     Document Type: Article

References (32)

1. Pletcher MJ, Tice JA, Pignone M, Browner WS. Using the coronary artery calcium score to predict coronary heart disease events: a systematic review and meta-analysis. Arch Intern Med 2004;164:1285-1292.
2. Budoff MJ, Shaw LJ, Liu ST, Weinstein SR, Mosler TP, Tseng PH, Flores FR, Callister TQ, Raggi P, Berman DS. Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients. J Am Coll Cardiol 2007;49:1860-1870.
3. Shaw LJ, Raggi P, Schisterman E, Berman DS, Callister TQ. Prognostic value of cardiac risk factors and coronary artery calcium screening for all-cause mortality. Radiology 2003;228:826-833.
4. Greenland P, Alpert JS, Beller GA, Benjamin EJ, Budoff MJ, Fayad ZA, Foster E, Hlatky MA, Hodgson JMcB, Kushner FG, Lauer MS, Shaw LJ, Smith SC Jr, Taylor AJ, Weintraub WS, Wenger NK. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the ACCF/AHA Task Force on Practice Guidelines. J Am Coll Cardiol 2010;56:e50-e103.
5. Perrone-Filardi P, Achenbach S, Mohlenkamp S, Reiner Z, Sambuceti G, Schuijf JD, Van derWall E, Kaufmann PA, Knuuti J, Schroeder S, Zellweger MJ. Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: a position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology. Eur Heart J 2011;32:1986-1993.
6. De Ruijter W, Westendorp RG, Assendelft WJ, Den Elzen WP, De Craen AJ, Le Cessie S, Gussekloo J. Use of Framingham risk score and new biomarkers to predict cardiovascular mortality in older people: population based observational cohort study. Br Med J 2009;338:a3083.
7. Zarich S, Luciano C, Hulford J, Abdullah A. Prevalence of metabolic syndrome in young patients with acute MI: does the Framingham Risk Score underestimate cardiovascular risk in this population? Diab Vasc Dis Res 2006;3:103-107.
8. Tota-Maharaj R, Blaha MJ, Rivera JJ, Henry TS, Choi E, Chang S, Yoon YE, Chun EJ, Choi S, Blumenthal RS, Chang H, Nasir K. Differences in coronary plaque composition with aging measured by coronary computed tomography angiography. Int J Cardiol 2011; doi:10.1016/j.ijcard.2011.01.041.
9. Taylor AJ, Fiorilli PN, Hongyan W, Bauer K, Bindeman J, Byrd C, Feuerstein IM, O'Malley PG. Relation between the Framingham risk score, coronary calcium, and incident coronary heart disease among low-risk men. Am J Cardiol 2010; 106:47-50.
10. Kronmal RA, McClelland RL, Detrano R, Shea S, Lima JA, Cushman M, Bild DE, Burke GL. Risk factors for the progression of coronary artery calcification in asymptomatic subjects results from the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation 2007;115:2722-2730.
11. Fleckenstein A, Frey M, Thimm F, Fleckenstein-Grun G. Excessive mural calcium overload-a predominant causal factor in the development of stenosing coronary plaques in humans. Cardiovasc Drugs Ther 1990;4:1005-1014.
12. Stanford W, Thompson BH, Weiss RM. Coronary artery calcification: clinical significance and current methods of detection. Am J Roentgenol 1993;161: 1139-1146.
13. Vliegenthart R, Oudkerk M, Hofman A, Oei HS, Van Dijck W, Van Rooij FJ, Witteman JC. Coronary calcification improves cardiovascular risk prediction in the elderly. Circulation 2005;112:572-577.
14. Raggi P, Gongora MC, Gopal A, Callister TQ, Budoff M, Shaw LJ. Coronary artery calcium to predict all-cause mortality in elderly men and women. J Am Coll Cardiol 2008;52:17-23.
15. Blaha M, Budoff MJ, Shaw LJ, Khosa F, Rumberger JA, Berman D, Callister T, Raggi P, Blumenthal RS, Nasir K. Absence of coronary artery calcification and allcause mortality. J Am Coll Cardiol Img 2009;2:692-700.
16. Agatston A, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M Jr, Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 1990;15:827-832.
17. Table 122: Deaths and Death Rates by Leading Causes of Death and Age: 2007. The 2012 Statistical Abstract: Births, Deaths, Marriages and Divorces website. http://www.census.gov/compendia/statab/cats/births-deaths-marriages- divorces. html. (4 June 2012).
18. Nakashima Y, Kiyohara Y, Doi Y, Kubo M, Lida M, Sueishi K. Risk factors for coronary atherosclerosis in a general Japanese population: the Hisayama study. Pathol Res Pract 2009;205:700-708.
19. LaMonte MJ, FitzGerald SJ, Church TS, Barlow CE, Radford NB, Levine BD, Pippin JJ, Gibbons LW, Blair SN, Nichaman MZ. Coronary artery calcium score and coronary heart disease events in a large cohort of asymptomatic men and women. Am J Epidemiol 2005;162:421-429.
20. Rozanski A, Gransar H, Shaw LJ, Kim J, Miranda-Peats L, Wong ND, Rana JS, Orakzai R, Hayes SW, Friedman JD, Thomson LE, Polk D, Min J, Budoff MJ, Berman DS. Impact of coronary artery calcium scanning on coronary risk factors and downstream testing: the EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) Prospective Randomized Trial. J Am Coll Cardiol 2011;57:1622-1632.
21. Nelson MR, Liew D, Bertram M, Vos T. Epidemiological modelling of routine use of low dose aspirin for the primary prevention of coronary heart disease and stroke in those aged ≥70. Br Med J 2005;330:1306.
22. Robinson JG. Lipid-lowering therapy for the primary prevention of cardiovascular disease in the elderly: opportunities and challenges. Drugs Aging 2009;26: 917-931.
23. Masaki KH, Schatz IJ, Burchfiel CM, Sharp DS, Chiu D, Foley D, Curb JD. Orthostatic hypotension predicts mortality in elderly men: The Honolulu Heart Program. Circulation 1998;98:2290-2295.
24. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, Jones DW, Materson BJ, Oparil S, Wright JT, Roccella EJ; and the National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 Report. JAMA 2003;289:2560-2572.
25. Loria CM, Liu K, Lewis CE, Hulley SB, Sidney S, Schreiner PJ, Williams OD, Bild DE, Detrano R. Early adult risk factor levels and subsequent coronary artery calcification: the CARDIA Study. J Am Coll Cardiol 2007;49:2013-2020.
26. Taylor AJ, BindemanJ, Feuerstein I, CaoF, BrazaitisM,O'Malley PG.Coronary calcium independently predicts incident premature coronary heart disease over measured cardiovascular risk factors:mean three-year outcomes in the Prospective Army Coronary Calcium (PACC) project. J Am Coll Cardiol 2005;46:807-814.
27. Meier P, Hemingway H, Lansky AJ, Knapp G, Pitt B, Seiler C. The impact of the coronary collateral circulation on mortality: a meta-analysis. Eur Heart J 2012; 33:614-621.
28. Berry C, Balachandran KP, L'Allier PL, Lesperance J, Bonan B, Oldroyd KG. Importance of collateral circulation in coronary heart disease. Eur Heart J 2007; 28:278-291.
29. McClelland RL, Nasir K, Budoff M, Blumenthal RS, Kronmal RA. Arterial age as a function of coronary artery calcium (from the Multi-Ethnic Study of Atherosclerosis [MESA]). Am J Cardiol 2009;103:59-63.
30. Hoff JA, Daviglus ML, Chomka EV, Krainik AJ, Sevrukov A, Kondos GT. Conventional coronary artery disease risk factors and coronary artery calcium detected by electron beam tomography in 30 908 healthy individuals. Ann Epidemiol 2003; 13:163-169.
31. Coughlin SS. Recall Bias in Epidemiologic Studies. J Clin Epidemiol 1990;43:87-91.
32. Blair SN, Goodyear NN, Gibbons LW, Cooper KH. Physical fitness and incidence of hypertension in healthy normotensive men and women. JAMA 1984;252: 487-490.