Effects of Salusin-β on action potential and ionic currents in ventricular myocytes of rats

Acta Physiologica

Volumn 207, Issue 1, 2013, Pages 166-172

  Ren, An Jing ^a   Liang, Qing ^a,b   Wang, Rong ^b   Ji, Hai Yu ^b   Wu, Yi ^b   Shi, Jing Song ^c   Lin, Li ^a   Yuan, Wen Jun ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

^c NANJING GENERAL HOSPITAL OF NANJING MILITARY COMMAND   (China)

Author keywords

Action potential; Ionic currents; Myocytes; Salusin

Indexed keywords

MUSCLE PROTEIN; SALUSIN BETA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE POTENTIAL; HEART VENTRICLE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SODIUM CALCIUM EXCHANGE; SODIUM CURRENT; VOLTAGE CLAMP;

ACTION POTENTIALS; ANIMALS; CELLS, CULTURED; HEART VENTRICLES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE POTENTIALS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; SODIUM CHANNELS; SODIUM-CALCIUM EXCHANGER;

EID: 84870792711     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2012.02475.x     Document Type: Article

References (26)

1. Apkon, M. & Nerbonne, J.M. 1991. Characterization of two distinct depolarization-activated K+ currents in isolated adult rat ventricular myocytes. J Gen Physiol 97, 973-1011.
2. Bouchard, R.A., Clark, R.B. & Giles, W.R. 1995. Effects of action potential duration on excitation-contraction coupling in rat ventricular myocytes. Action potential voltage-clamp measurements. Circ Res 76, 790-801.
3. Coraboeuf, E. 1969. Some considerations about the cardiac action potential plateau. J Electrocardiol 2, 91-94.
4. Davies, L.A., Hopkins, P.M., Boyett, M.R. & Harrison, S.M. 2000. Effects of halothane on the transient outward K(+) current in rat ventricular myocytes. Br J Pharmacol 131, 223-230.
5. + dependence. J Physiol 435, 395-420.
6. Fedida, D. & Bouchard, R.A. 1992. Mechanisms for the positive inotropic effect of alpha 1-adrenoceptor stimulation in rat cardiac myocytes. Circ Res 71, 673-688.
7. + currents in rat ventricular myocytes. Am J Physiol Heart Circ Physiol 285, H661-H668.
8. Izumiyama, H., Tanaka, H., Egi, K., Sunamori, M., Hirata, Y. & Shichiri, M. 2005. Synthetic salusins as cardiac depressors in rat. Hypertension 45, 419-425.
9. Josephson, I.R., Sanchez-Chapula, J. & Brown, A.M. 1984. Early outward current in rat single ventricular cells. Circ Res 54, 157-162.
10. Kimoto, S., Sato, K., Watanabe, T., Suguro, T., Koyama, T. & Shichiri, M. 2010. Serum levels and urinary excretion of salusin-alpha in renal insufficiency. Regul Pept 162, 129-132.
11. Mitchell, M.R., Powell, T., Terrar, D.A. & Twist, V.W. 1984. The effects of ryanodine, EGTA and low-sodium on action potentials in rat and guinea-pig ventricular myocytes: evidence for two inward currents during the plateau. Br J Pharmacol 81, 543-550.
12. Nakayama, C., Shichiri, M., Sato, K. & Hirata, Y. 2009. Expression of prosalusin in human neuroblastoma cells. Peptides 30, 1362-1367.
13. Nichols, C.G., Makhina, E.N., Pearson, W.L., Sha, Q. & Lopatin, A.N. 1996. Inward rectification and implications for cardiac excitability. Circ Res 78, 1-7.
14. Persson, P.B. & Henriksson, J. 2011. Editorial. Acta Physiol 203, 403-407.
15. Sato, K., Koyama, T. & Shichiri, M. 2008. Biosynthesis and secretion of salusin-alpha from human cells. Peptides 29, 2203-2207.
16. Sato, K., Sato, T., Susumu, T., Koyama, T. & Shichiri, M. 2009. Presence of immunoreactive salusin-beta in human plasma and urine. Regul Pept 158, 63-67.
17. Sato, K., Fujimoto, K., Koyama, T. & Shichiri, M. 2010. Release of salusin-beta from human monocytes/macrophages. Regul Pept 162, 68-72.
18. Schouten, V.J. & ter Keurs, H.E. 1985. The slow repolarization phase of the action potential in rat heart. J Physiol 360, 13-25.
19. Shi, J.S., Li, D., Li, N., Lin, L., Yang, Y.J., Tang, Y., Sun, T., Yuan, W.J. & Ren, A.J. 2010. Inhibition of L-type calcium currents by salusin-beta in rat cardiac ventricular myocytes. Peptides 31, 1146-1149.
20. Shichiri, M., Ishimaru, S., Ota, T., Nishikawa, T., Isogai, T. & Hirata, Y. 2003. Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities. Nat Med 9, 1166-1172.
21. Suzuki, N., Shichiri, M., Akashi, T., Sato, K., Sakurada, M., Hirono, Y., Yoshimoto, T., Koyama, T. & Hirata, Y. 2007. Systemic distribution of salusin expression in the rat. Hypertens Res 30, 1255-1262.
22. Takenoya, F., Hori, T., Kageyama, H., Funahashi, H., Takeuchi, M., Kitamura, Y., Shichiri, M. & Shioda, S. 2005. Coexistence of salusin and vasopressin in the rat hypothalamo-hypophyseal system. Neurosci Lett 385, 110-113.
23. Watanabe, T., Nishio, K., Kanome, T., Matsuyama, T.A., Koba, S., Sakai, T., Sato, K., Hongo, S., Nose, K., Ota, H., Kobayashi, Y., Katagiri, T., Shichiri, M. & Miyazaki, A. 2008. Impact of salusin-alpha and -beta on human macrophage foam cell formation and coronary atherosclerosis. Circulation 117, 638-648.
24. Wood, E.H., Heppner, R.L. & Weidmann, S. 1969. Inotropic effects of electric currents. I. Positive and negative effects of constant electric currents or current pulses applied during cardiac action potentials. II. Hypotheses: calcium movements, excitation-contraction coupling and inotropic effects. Circ Res 24, 409-445.
25. Xiao-Hong, Y., Li, L., Yan-Xia, P., Hong, L., Wei-Fang, R., Yan, L., An-Jing, R., Chao-Shu, T. & Wen-Jun, Y. 2006. Salusins protect neonatal rat cardiomyocytes from serum deprivation-induced cell death through upregulation of GRP78. J Cardiovasc Pharmacol 48, 41-46.
26. Yu, F., Zhao, J., Yang, J., Gen, B., Wang, S., Feng, X., Tang, C. & Chang, L. 2004. Salusins promote cardiomyocyte growth but does not affect cardiac function in rats. Regul Pept 122, 191-197.