Impact of salusin-α and -β on human macrophage foam cell formation and coronary atherosclerosis

Circulation

Volumn 117, Issue 5, 2008, Pages 638-648

  Watanabe, Takuya ^a,b   Nishio, Kae ^a   Kanome, Tomoko ^a   Matsuyama, Taka Aki ^a   Koba, Shinji ^b   Sakai, Tetsuo ^b   Sato, Kengo ^d   Hongo, Shigeki ^a   Nose, Kiyoshi ^c   Ota, Hidekazu ^a   Kobayashi, Youichi ^b   Katagiri, Takashi ^b   Shichiri, Masayoshi ^d   Miyazaki, Akira ^a  

^a Department of Biochemistry ^*

^b SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SHOWA UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Atherosclerosis; Coronary disease; Peptides; plaque; Salusin , human; Salusin , human

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; GUANINE NUCLEOTIDE BINDING PROTEIN; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; PROTEIN; PROTEIN TYROSINE KINASE; SALUSIN ALPHA; SALUSIN BETA; SCAVENGER RECEPTOR A; UNCLASSIFIED DRUG; ACAT1 PROTEIN, HUMAN; ACETYL COENZYME A ACETYLTRANSFERASE; ACETYL LOW DENSITY LIPOPROTEIN; ACETYL-LDL; ISOPROTEIN; SIGNAL PEPTIDE; TOR2A PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL CULTURE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; ENDOCYTOSIS; FEMALE; FIBROBLAST; FOAM CELL; HUMAN; HUMAN CELL; HYPERTENSION; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; VASCULAR SMOOTH MUSCLE; VOLUNTEER; ATHEROSCLEROSIS; BLOOD; CELL DIFFERENTIATION; CORONARY ARTERY DISEASE; CORONARY BLOOD VESSEL; CULTURE TECHNIQUE; CYTOLOGY; ENZYMOLOGY; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACETYL-COA C-ACETYLTRANSFERASE; ATHEROSCLEROSIS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CHOLESTEROL ESTERS; CORONARY DISEASE; CORONARY VESSELS; ENDOCYTOSIS; FOAM CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPROTEINS, LDL; MACROPHAGES; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 40149089744     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.712539     Document Type: Article

References (25)

1. Shichiri M, Ishimaru S, Ota T, Nishikawa T, Isogai T, Hirata Y. Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities. Nat Med. 2003;9:1166 -1172.
2. Sato K, Koyama T, Tateno T, Hirata Y, Shichiri M. Presence of immunoreactive salusin in human serum and urine. Peptides. 2006;27: 2561-2566.
3. Izumiyama H, Tanaka H, Egi K, Sunamori M, Hirata Y, Shichiri M. Synthetic salusins as cardiac depressors in rat. Hypertension. 2005;45: 419-425.
4. Yu F, Zhao J, Yang J, Gen B, Wang S, Feng X, Tang C, Chang L. Salusins promote cardiomyocyte growth but does not affect cardiac function in rats. Regul Pept. 2004;122:191-197.
5. Hong-Xiao Y, Li L, Yan-Xia P, Hong Lu, Wei-Fang R, Yan L, An-Jing R, Chao-Shu T, Wen-Jun Y. Salusins protect neonatal rat cardiomyocytes from serum deprivation-induced cell death through upregulation of GRP78. J Cardiovasc Pharmacol. 2006;48:41-46.
6. Pennings M, Meurs I, Ye D, Out R, Hoekstra M, Van Berkel TJC, Van Eck M. Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development. FEBS Lett. 2006;580: 5588-5596.
7. Chang TY, Chang CC, Lin S, Yu C, Li BL, Miyazaki A. Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2. Curr Opin Lipidol. 2001;12:289 -296.
8. Miyazaki A, Sakashita N, Lee O, Takahashi K, Horiuchi S, Hakamata H, Morganelli PM, Chang CC, Chang TY. Expression of ACAT-1 protein in human atherosclerotic lesions and cultured human monocytes-macrophages. Arterioscler Thromb Vasc Biol. 1998;18:1568 -1574.
9. Hori M, Miyazaki A, Tamagawa H, Satoh M, Furukawa K, Hakamata H, Sasaki Y, Horiuchi S. Up-regulation of acyl-coenzyme A:cholesterol acyltransferase-1 by transforming growth factor-1 during differentiation of human monocytes into macrophages. Biochem Biophys Res Commun. 2004;320:501-505.
10. Watanabe T, Suguro T, Kanome T, Sakamoto Y, Kodate S, Hagiwara T, Hongo S, Hirano T, Adachi M, Miyazaki A. Human urotensin II accelerates foam cell formation in human monocyte-derived macrophages. Hypertension. 2005;46:738 -744.
11. Suguro T, Watanabe T, Kanome T, Kodate S, Hirano T, Miyazaki A, Adachi M. Serotonin acts as an up-regulator of acyl-coenzyme A:cholesterol acyltransferase-1 in human monocyte-macrophages. Atherosclerosis. 2006;186:275-281.
12. Shichiri M. Reply to "Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities." Nat Med. 2007;13:661-662.
13. Ding Q, Jin T, Wang Z, Chen Y. Catalase potentiates retinoic acidinduced THP-1 monocyte differentiation into macrophage through inhibition of peroxisome proliferator-activated receptor. J Leukoc Biol. 2007;81:1568 -1576.
14. Gough PJ, Greaves DR, Suzuki H, Hakkinen T, Hiltunen MO, Turunen M, Herttuala SY, Kodama T, Gordon S. Analysis of macrophage scavenger receptor (SR-A) expression in human aortic atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 1999;19:461-471.
15. Schmitz G, Kaminski WE, Porsch-Ozcurumez M, Klucken J, Orso E, Bodzioch M, Buchler C, Drobnik W. ATP-binding cassette transporter A1 (ABCA1) in macrophages: a dual function in inflammation and lipid metabolism? Pathobiology. 1999;67:236 -240.
16. Wang Z, Takahashi T, Saito Y, Nagasaki H, Ly NK, Nothacker HP, Reinscheid RK, Yang J, Chang JK, Shichiri M, Civelli O. Salusin β is a surrogate ligand of the mas-like G protein-coupled receptor MrgA1. Eur J Pharmacol. 2006;539:145-150.
17. Yang JB, Duan ZJ, Yao W, Lee O, Yang L, Yang XY, Sun X, Chang CC, Chang TY, Li BL. Synergistic transcriptional activation of human acylcoenzyme A:cholesterol acyltransferase-1 gene by interferon and alltrans- retinoic acid THP-1 cells. J Biol Chem. 2001;276:20989 -20998.
18. Cheng W, Kvilekval KV, Abumrad NA. Dexamethasone enhances accumulation of cholesteryl esters by human macrophages. Am J Physiol. 1995;269:E642-E648.
19. Ng MKC, Nakhla S, Baoutina A, Jessup W, Handelsman DJ, Celermajer DS. Dehydroepiandrosterone, an adrenal androgen, increases human foam cell formation. J Am Coll Cardiol. 2003;42:1967-1974.
20. Watanabe T, Kanome T, Miyazaki A, Katagiri T. Human urotensin II linking hypertension and coronary artery disease. Hypertens Res. 2006; 29:375-387.
21. Furukawa K, Hori M, Ouchi N, Kihara S, Funahashi T, Matsuzawa Y, Miyazaki A, Nakayama H, Horiuchi S. Adiponectin down-regulates acylcoenzyme A:cholesterol acyltransferase-1 in cultured human monocytederived macrophages. Biochem Biophys Res Commun. 2004;317: 831-836.
22. Ashton JH, Benedict CR, Fitzgerald C, Raheja S, Taylor A, Campbell WB, Buja LM, Willerson JT. Serotonin as a mediator of cyclic flow variations in stenosed canine coronary arteries. Circulation. 1986;73: 572-578.
23. Leosco D, Fineschi M, Pierli C, Fiaschi A, Ferrara N, Bianco S, Longobardi G, Pisani E, Bravi A, Rengo F. Intracoronary serotonin release after high-pressure coronary stenting. Am J Cardiol. 1999;84:1317-1322.
24. Russell FD, Meyers D, Galbraith AJ, Bett N, Toth I, Kearns P, Molenaar P. Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. Am J Physiol Heart Circ Physiol. 2003;285: H1576-H1581.
25. Schuijt MP, van Kats JP, de Zeeuw S, Duncker DJ, Verdouw PD, Schalekamp MADH, Danser AHJ. Cardiac interstitial fluid levels of angiotensin I and II in the pig. J Hypertens. 1999;17:1885-1891.