Neuronal overexpression of IP3 receptor 2 is detrimental in mutant SOD1 mice

Biochemical and Biophysical Research Communications

Volumn 429, Issue 3-4, 2012, Pages 210-213

  Staats, Kim A ^a,b   Bogaert, Elke ^a,b   Hersmus, Nicole ^a,b   Jaspers, Tom ^a,b   Luyten, Tomas ^c   Bultynck, Geert ^c   Parys, Jan B ^c   Hisatsune, Chihiro ^d   Mikoshiba, Katsuhiko ^d   Van Damme, Philip ^a,b,e   Robberecht, Wim ^a,b,e   Van Den Bosch, Ludo ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

^d RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^e UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

ALS; Amyotrophic Lateral Sclerosis; Ca2+; Excitotoxicity; IP3 receptors; Motor neuron disease

Indexed keywords

BRADYKININ; CALCIUM CHANNEL; CALCIUM ION; COPPER ZINC SUPEROXIDE DISMUTASE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR 2; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CALCIUM CELL LEVEL; CALCIUM METABOLISM; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; EXCITOTOXICITY; EXPERIMENTAL MODEL; LIFESPAN; MOTONEURON; MOUSE; MOUSE MUTANT; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; SUPEROXIDE DISMUTASE;

MUS;

EID: 84870710356     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.10.094     Document Type: Article

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