Ectopically expressed IBP promotes cell proliferation in oral squamous cell carcinoma

Cancer Investigation

Volumn 30, Issue 10, 2012, Pages 748-756

  Jian, Cong Xiang ^a,b   Yang, Ming Zhen ^a   Li, Peng ^a   Xiong, Jian ^a   Zhang, Zhu Jun ^a   Li, Chen Jun ^b   Chen, An ^a   Hu, Chuan Min ^a   Zhou, Ji Xiang ^a   Li, Shu Hui ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHENGDU MILITARY GENERAL HOSPITAL   (China)

Author keywords

Cell cycle; Interferon regulatory factor 4 (IRF 4) binding protein (IBP); Oral squamous cell carcinoma (OSCC); Proliferation

Indexed keywords

CYCLIN D1; INTERFERON REGULATORY FACTOR 4; INTERFERON REGULATORY FACTOR 4 BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER STAGING; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DISTANT METASTASIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOUSE; MOUTH MUCOSA; MOUTH SQUAMOUS CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR DIFFERENTIATION; TUMOR VOLUME;

ANIMALS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; DNA-BINDING PROTEINS; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; MOUTH NEOPLASMS; NEOPLASM STAGING; NUCLEAR PROTEINS; TISSUE ARRAY ANALYSIS; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR MARKERS, BIOLOGICAL;

EID: 84870705888     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357907.2012.734355     Document Type: Article

References (25)

1. Petersen PE.TheWorld Oral Health report 2003: continuous improvement of oral health in the 21st century-the approach of the WHO Global Oral Health Programme. Community Dent Oral Epidemiol 2003;31(Suppl 1): 3-23.
2. Petersen PE. Global policy for improvement of oral health in the 21st century-implications to oral health research ofWorld Health Assembly 2007, World Health Organization. Community Dent Oral Epidemiol 2009;37(1): 1-8.
3. Tsui IF, Garnis C, Poh CF. A dynamic oral cancer field: unraveling the underlying biology and its clinical implication. Am J Surg Pathol 2009;33(11): 1732-1738.
4. Kao SY, Chu YW, Chen YW, Chang KW, Liu TY. Detection and screening of oral cancer and pre-cancerous lesions. J Chin Med Assoc 2009;72(5): 227-233.
5. Lazer G, Katzav S. Guanine nucleotide exchange factors for RhoGTPases: good therapeutic targets for cancer therapy? Cell Signal 2011;23(6): 969-979.
6. Gupta S. Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system. Hum Immunol 2003;64(4): 389-401.
7. Mavrakis KJ, McKinlay KJ, Jones P, Sablitzky F. DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA. Exp Cell Res 2004;294(2): 335-344.
8. Gupta S, Fanzo JC, Hu C, Cox D, Jang SY, Lee AE, Greenberg S, Pernis AB. T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse. J Biol Chem 2003;278(44): 43541-43549.
9. B́ecart S, Charvet C, Canonigo Balancio AJ, De Trez C, Tanaka Y, Duan W,Ware C, Croft M, Altman A. SLAT regulatesTh1 and Th2inflammatory responses by controlling Ca2+/NFAT signaling. J Clin Invest 2007;117(8): 2164-2175.
10. Canonigo-Balancio AJ, Fos C, Prod'homme T, B́ecart S, Altman A. SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis. J Immunol 2009;183(11): 7259-7267.
11. Chen Q, Gupta S, Pernis AB. Regulation of TLR4-mediated signaling by IBP/Def6, a novel activator of Rho GTPases. J Leukoc Biol 2009;85(3): 539-543.
12. Oka T, Ihara S, Fukui Y. Cooperation of DEF6 with activated Rac in regulating cell morphology. J Biol Chem 2007;282(3): 2011-2018.
13. Subramanian S, West RB, Marinelli RJ, Nielsen TO, Rubin BP, Goldblum JR, Patel RM, Zhu S, Montgomery K, Ng TL, Corless CL, Heinrich MC, van de Rijn M The gene expression profile of extraskeletal myxoid chondrosarcoma. J Pathol 2005;206(4): 433-444.
14. Zhang Z, Wang Q, Li P, Zhou Y, Li S, Yi W, Chen A, Kong P, Hu C. Overexpression of the interferon regulatory factor 4-binding protein in human colorectal cancer and its clinical significance. Cancer Epidemiol 2009;33(2): 130-136.
15. Li P, Zhang Z, Wang Q, Li S, Zhang Y, Bian X, Chen A, Hu C. The ectopic expression of IFN regulatory factor 4-binding protein is correlated with the malignant behavior of human breast cancer cells. Int Immunopharmacol 2009;9(7-8): 1002-1009.
16. Tang S, Yang G,Meng Y, Du R, Li X, Fan R, Zhao L, Bi Q, Jin J, Gao L, Zhang L, LiH, FanM, Wang Y, Wu K, Liu J, Fan D. Overexpression of a novel gene gankyrin correlates with the malignant phenotype of colorectal cancer. Cancer Biol Ther 2010;9(2): 88-95.
17. He L,Wang H, Jin H, Guo C, Xie H, Yan K, Li X, Shen Q, Qiao T, Chen G, Chai N, Zhao L,Dong Q, Zheng Y, Liu J, FanD. CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma. Cancer Lett 2009;276(1): 88-94.
18. Li S, Chai Z, Li Y, Liu D, Bai Z, Li Y, Li Y, Situ Z. BZW1, a novel proliferation regulator that promotes growth of salivary mucoepidermoid carcinoma. Cancer Lett 2009;284(1): 86-94.
19. Hardisson D.Molecular pathogenesis of head and neck squamous cell carcinoma. Eur Arch Otorhinolaryngol 2003;260(9): 502-508.
20. Pruitt K,DerCJ. Ras and Rho regulation of the cell cycle and oncogenesis. Cancer Lett 2001;171(1): 1-10.
21. Michalides RJ, van de Brekel M, Balm F. Defects in G1-S cell cycle control in head and neck cancer: a review. Head Neck 2002;24(7): 694-704.
22. Zhang T, Zheng J, Jiang N, Wang G, Shi Q, Liu C, Lu Y. Overexpression of DLC-1 induces cell apoptosis and proliferation inhibition in the renal cell carcinoma. Cancer Lett 2009;283(1): 59-67.
23. Morin P, Flors C, Olson MF. Constitutively active RhoA inhibits proliferation by retarding G1 to S phase cell cycle progression and impairing cytokinesis. Eur J Cell Biol 2009;88(9): 495-507.
24. Karlsson R, Pedersen ED, Wang Z, Brakebusch C. Rho GTPase function in tumorigenesis. Biochim Biophys Acta 2009;1796(2): 91-98.
25. Ellenbroek SI, Collard JG. Rho GTPases: functions and association with cancer. Clin Exp Metastasis 2007;24(8): 657-662.