A highly efficient, high-throughput lipidomics platform for the quantitative detection of eicosanoids in human whole blood

Analytical Biochemistry

Volumn 433, Issue 2, 2013, Pages 181-188

  Song, Jiao ^a   Liu, Xuejun ^a   Wu, Jiejun ^a   Meehan, Michael J ^b   Blevitt, Jonathan M ^a   Dorrestein, Pieter C ^b   Milla, Marcos E ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Automated software; Eicosanoids; High throughput platform; Human whole blood; Lipidomics; UPLC MRM MS

Indexed keywords

CALCIUM; IONOPHORES; LIQUID CHROMATOGRAPHY;

EICOSANOIDS; HIGH THROUGHPUT; LIPIDOMICS; UPLC-MRM/MS; WHOLE BLOOD;

BLOOD;

CALCIUM IONOPHORE; ICOSANOID; LIPID;

ACCURACY; ALGORITHM; ARTICLE; BLOOD; CALIBRATION; EX VIVO STUDY; FATTY ACID ANALYSIS; IN VIVO STUDY; LIPIDOMICS; MASS SPECTROMETER; MASS SPECTROMETRY; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY MULTIPLE REACTION MONITORING MASS SPECTROMETRY;

EID: 84870702021     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.10.022     Document Type: Article

References (19)

1. 2 from arachidonic acid prostaglandins and related factors 32 Biochim. Biophys. Acta 90 1964 207 210
2. C.D. Funk Prostaglandins and leukotrienes: advances in eicosanoid biology Science 294 2001 1871 1875
3. W.W. Busse, and R.F. Lemanske Jr. Asthma N. Engl. J. Med. 344 2001 350 362
4. A. Koeberle, U. Siemoneit, H. Northoff, B. Hofmann, G. Schneider, and O. Werz MK-886, an inhibitor of the 5-lipoxygenase-activating protein, inhibits cyclooxygenase-1 activity and suppresses platelet aggregation Eur. J. Pharmacol. 608 2009 84 90
5. J. Claria, and M. Romano Pharmacological intervention of cyclooxygenase-2 and 5-lipoxygenase pathways: impact on inflammation and cancer Curr. Pharm. Des. 11 2005 3431 3447
6. H. Harizi, J.B. Corcuff, and N. Gualde Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology Trends Mol. Med. 14 2008 461 469
7. G. Folco, and R.C. Murphy Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses Pharmacol. Rev. 58 2006 375 388
8. O. Radmark, and B. Samuelsson Regulation of 5-lipoxygenase enzyme activity Biochem. Biophys. Res. Commun. 338 2005 102 110
9. J.W. Woods, J.F. Evans, D. Ethier, S. Scott, P.J. Vickers, L. Hearn, J.A. Heibein, S. Charleson, and I.I. Singer 5-Lipoxygenase and 5-lipoxygenase- activating protein are localized in the nuclear envelope of activated human leukocytes J. Exp. Med. 178 1993 1935 1946
10. A.D. Ferguson, B.M. McKeever, S. Xu, D. Wisniewski, D.K. Miller, T.T. Yamin, R.H. Spencer, L. Chu, F. Ujjainwalla, B.R. Cunningham, J.F. Evans, and J.W. Becker Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein Science 317 2007 510 512
11. M. Peters-Golden, and T.G. Brock 5-Lipoxygenase and FLAP Prostaglandins Leukot. Essent. Fatty Acids 69 2003 99 109
12. F. Gaber, K. Daham, A. Higashi, N. Higashi, A. Gulich, I. Delin, A. James, M. Skedinger, P. Gyllfors, M. Nord, S.E. Dahlen, M. Kumlin, and B. Dahlen Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine, and blood from patients with aspirin-intolerant asthma Thorax 63 2008 1076 1082
13. 4 Curr. Opin. Allergy Clin. Immunol. 8 2008 154 157
14. A.P. Sampson, E. Pizzichini, and H. Bisgaard Effects of cysteinyl leukotrienes and leukotriene receptor antagonists on markers of inflammation J. Allergy Clin. Immunol. 111 2003 S49 S59 discussion S59-S61
15. M. Kapoor, F. Kojima, M. Qian, L. Yang, and L.J. Crofford Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis FASEB J. 20 2006 2387 2389
16. P. Marcouiller, J.P. Pelletier, M. Guevremont, J. Martel-Pelletier, P. Ranger, S. Laufer, and P. Reboul Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1β synthesis J. Rheumatol. 32 2005 704 712
17. D.S. Dumlao, M.W. Buczynski, P.C. Norris, R. Harkewicz, and E.A. Dennis High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines Biochim. Biophys. Acta 2011 1811 724 736
18. 4 in human whole blood J. Pharmacol. Toxicol. Methods 28 1992 185 190
19. 2 production in human whole blood and monocytes stimulated by lipopolysaccharide and A23187 Methods Find. Exp. Clin. Pharmacol. 28 2006 361 367