Mechanism for adaptive remodeling of the bacterial flagellar switch

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 49, 2012, Pages 20018-20022

  Lele, Pushkar P ^a   Branch, Richard W ^a   Nathan, Vedhavalli S J ^a   Berg, Howard C ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

Escherichia coli; Motility

Indexed keywords

BACTERIAL PROTEIN; FLIM PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL FLAGELLUM; BINDING AFFINITY; BINDING SITE; NONHUMAN; PRIORITY JOURNAL; ROTATION;

BACTERIAL PROTEINS; ESCHERICHIA COLI; FLAGELLA; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, CHEMICAL; MOLECULAR MOTOR PROTEINS; PROTEIN BINDING; ROTATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 84870599344     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1212327109     Document Type: Article

References (32)

1. Berg HC (2003) The rotary motor of bacterial flagella. Annu Rev Biochem 72:19-54.
2. Sarkar MK, Paul K, Blair D (2010) Chemotaxis signaling protein CheY binds to the rotor protein FliN to control the direction of flagellar rotation in Escherichia coli. Proc Natl Acad Sci USA 107(20):9370-9375.
3. Hazelbauer GL, Falke JJ, Parkinson JS (2008) Bacterial chemoreceptors: High-performance signaling in networked arrays. Trends Biochem Sci 33(1):9-19.
4. Yuan J, Branch RW, Hosu BG, Berg HC (2012) Adaptation at the output of the chemotaxis signalling pathway. Nature 484(7393):233-236.
5. Hazelbauer GL (2012) Microbiology: Adaptation by target remodelling. Nature 484 (7393):173-175.
6. Togashi F, Yamaguchi S, Kihara M, Aizawa SI, Macnab RM (1997) An extreme clockwise switch bias mutation in fliG of Salmonella typhimurium and its suppression by slow-motile mutations in motA and motB. J Bacteriol 179(9):2994-3003. (Pubitemid 27194450)
7. Minamino T, et al. (2011) Structural insight into the rotational switching mechanism of the bacterial flagellar motor. PLoS Biol 9(5):e1000616.
8. Sourjik V, Berg HC (2000) Localization of components of the chemotaxis machinery of Escherichia coli using fluorescent protein fusions. Mol Microbiol 37(4):740-751. (Pubitemid 30618137)
9. Thomas DR, Francis NR, Xu C, DeRosier DJ (2006) The three-dimensional structure of the flagellar rotor from a clockwise-locked mutant of Salmonella enterica serovar Typhimurium. J Bacteriol 188(20):7039-7048. (Pubitemid 44547609)
10. Scharf BE, Fahrner KA, Turner L, Berg HC (1998) Control of direction of flagellar rotation in bacterial chemotaxis. Proc Natl Acad Sci USA 95(1):201-206. (Pubitemid 28103931)
11. Cluzel P, Surette M, Leibler S (2000) An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells. Science 287(5458):1652-1655. (Pubitemid 30127766)
12. Sourjik V, Berg HC (2002) Binding of the Escherichia coli response regulator CheY to its target measured in vivo by fluorescence resonance energy transfer. Proc Natl Acad Sci USA 99(20):12669-12674.
13. Delalez NJ, et al. (2010) Signal-dependent turnover of the bacterial flagellar switch protein FliM. Proc Natl Acad Sci USA 107(25):11347-11351.
14. Li H, Sourjik V (2011) Assembly and stability of flagellar motor in Escherichia coli. Mol Microbiol 80(4):886-899.
15. Fukuoka H, Inoue Y, Terasawa S, Takahashi H, Ishijima A (2010) Exchange of rotor components in functioning bacterial flagellar motor. Biochem Biophys Res Commun 394(1):130-135.
16. Manson MD (2010) Dynamic motors for bacterial flagella. Proc Natl Acad Sci USA 107 (25):11151-11152.
17. Schulmeister S, et al. (2008) Protein exchange dynamics at chemoreceptor clusters in Escherichia coli. Proc Natl Acad Sci USA 105(17):6403-6408. (Pubitemid 351758358)
18. Wu J, Shekhar N, Lele PP, Lele TP (2012) FRAP analysis: Accounting for bleaching during image capture. PLoS ONE 7(8):e42854.
19. Passmore SE, Meas R, Marykwas DL (2008) Analysis of the FliM/FliG motor protein interaction by two-hybrid mutation suppression analysis. Microbiology 154(Pt 3):714-724. (Pubitemid 351736286)
20. Paul K, Brunstetter D, Titen S, Blair DF (2011) A molecular mechanism of direction switching in the flagellar motor of Escherichia coli. Proc Natl Acad Sci USA 108(41):17171-17176.
21. Young HS, Dang H, Lai Y, DeRosier DJ, Khan S (2003) Variable symmetry in Salmonella typhimurium flagellar motors. Biophys J 84(1):571-577. (Pubitemid 36026425)
22. Bai F, et al. (2010) Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch. Science 327(5966):685-689.
23. Ma Q, Nicolau DV, Jr., Maini PK, Berry RM, Bai F (2012) Conformational spread in the flagellar motor switch: A model study. PLOS Comput Biol 8(5):e1002523.
24. Duke TA, Le Novère N, Bray D (2001) Conformational spread in a ring of proteins: A stochastic approach to allostery. J Mol Biol 308(3):541-553. (Pubitemid 33027618)
25. Sowa Y, Berry RM (2008) Bacterial flagellar motor. Q Rev Biophys 41(2):103-132.
26. Brown PN, Terrazas M, Paul K, Blair DF (2007) Mutational analysis of the flagellar protein FliG: Sites of interaction with FliM and implications for organization of the switch complex. J Bacteriol 189(2):305-312. (Pubitemid 46106362)
27. Monod J, Wyman J, Changeux JP (1965) On nature of allosteric transitions - A plausible model. J Mol Biol 12:88-118.
28. Alon U, et al. (1998) Response regulator output in bacterial chemotaxis. EMBO J 17 (15):4238-4248. (Pubitemid 28362614)
29. Manson MD (2007) How 34 pegs fit into 26 + 8 holes in the flagellar motor. J Bacteriol 189(2):291-293.
30. Datsenko KA, Wanner BL (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97(12):6640-6645. (Pubitemid 30412767)
31. Yuan J, Berg HC (2008) Resurrection of the flagellar rotary motor near zero load. Proc Natl Acad Sci USA 105(4):1182-1185. (Pubitemid 351397027)
32. Yuan J, Fahrner KA, Berg HC (2009) Switching of the bacterial flagellar motor near zero load. J Mol Biol 390(3):394-400.