Acute inflammation induces insulin-like growth factor-1 to mediate Bcl-2 and Muc5ac expression in airway epithelial cells

American Journal of Respiratory Cell and Molecular Biology

Volumn 47, Issue 6, 2012, Pages 784-791

  Chand, Hitendra S ^a   Woldegiorgis, Zekarias ^a   Schwalm, Kurt ^a   McDonald, Jake ^a   Tesfaigzi, Yohannes ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Cell death; Cytokines; LPS aerosol; Mucus cell metaplasia; Retroviral shRNA

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MUCIN 5AC; PROTEIN BCL 2; SHORT HAIRPIN RNA; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; INFLAMMATION; LUNG DEPOSIT; MALE; METAPLASIA; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM;

ACUTE DISEASE; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CYTOKINES; EPITHELIAL CELLS; GENE EXPRESSION; HUMANS; HYPERPLASIA; INFLAMMATION MEDIATORS; INSULIN-LIKE GROWTH FACTOR I; LIPOPOLYSACCHARIDES; LUNG; MALE; METAPLASIA; MICE; MICE, INBRED C57BL; MUCIN 5AC; PNEUMONIA; PROTO-ONCOGENE PROTEINS C-BCL-2; RESPIRATORY MUCOSA;

MURINAE; MUS;

EID: 84870571558     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0079OC     Document Type: Article

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