-
1
-
-
57349134691
-
Chemical modification of siRNAs for in vivo use
-
DOI 10.1089/oli.2008.0164
-
BEHLKE, M. A. (2008). Chemical modification of siRNAs for in vivo use. Oligonucleotides 18, 305-319. (Pubitemid 352791344)
-
(2008)
Oligonucleotides
, vol.18
, Issue.4
, pp. 305-319
-
-
Behlke, M.A.1
-
2
-
-
84856389509
-
RNA-based therapeutics: Current progress and future prospects
-
BURNETT, J. C., and J. J. ROSSI (2012). RNA-based therapeutics: current progress and future prospects. Chem. Biol. 19, 60-71.
-
(2012)
Chem. Biol
, vol.19
, pp. 60-71
-
-
Burnett, J.C.1
Rossi, J.J.2
-
3
-
-
84857660324
-
Therapy for metastatic melanoma: The past, present, and future
-
FINN, L., S. N. MARKOVIC, et al. (2012). Therapy for metastatic melanoma: the past, present, and future. BMC Med. 10, 23.
-
(2012)
BMC Med
, vol.10
, pp. 23
-
-
Finn, L.1
Markovic, S.N.2
-
4
-
-
0015759232
-
In vitro cultivation of human tumors: Establishment of cell lines derived from a series of solid tumors
-
GIARD, D. J., S. A. AARONSON, et al. (1973). In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J. Natl. Cancer Inst. 51, 1417-1423.
-
(1973)
J. Natl. Cancer Inst
, vol.51
, pp. 1417-1423
-
-
Giard, D.J.1
Aaronson, S.A.2
-
5
-
-
69249229546
-
SiRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model
-
GONZALEZ-GONZALEZ, E., H. RA, et al. (2009). siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model. Gene Ther. 16, 963-972.
-
(2009)
Gene Ther
, vol.16
, pp. 963-972
-
-
Gonzalez-Gonzalez, E.1
Ra, H.2
-
6
-
-
77956263271
-
Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD)
-
GONZALEZ-GONZALEZ, E., T. J. SPEAKER, et al. (2010). Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD). Mol. Ther. 18, 1667-1674.
-
(2010)
Mol. Ther
, vol.18
, pp. 1667-1674
-
-
Gonzalez-Gonzalez, E.1
Speaker, T.J.2
-
7
-
-
84858988078
-
Metastatic melanoma: The new era of targeted therapy
-
GUIDA, M., S. PISCONTE, et al. (2012). Metastatic melanoma: the new era of targeted therapy. Expert Opin. Ther. Targets 16, S61-S70.
-
(2012)
Expert Opin. Ther. Targets
, vol.16
-
-
Guida, M.1
Pisconte, S.2
-
8
-
-
79954976090
-
Use of selfdelivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita model
-
HICKERSON, R. P., M. A. FLORES, et al. (2011a). Use of selfdelivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita model. J. Invest. Dermatol. 131, 1037-1044.
-
(2011)
J. Invest. Dermatol
, vol.131
, pp. 1037-1044
-
-
Hickerson, R.P.1
Flores, M.A.2
-
9
-
-
79954616664
-
Development of quantitative molecular clinical end points for siRNA clinical trials
-
HICKERSON, R. P., S. A. LEACHMAN, et al. (2011b). Development of quantitative molecular clinical end points for siRNA clinical trials. J. Invest. Dermatol. 131, 1029-1036.
-
(2011)
J. Invest. Dermatol
, vol.131
, pp. 1029-1036
-
-
Hickerson, R.P.1
Leachman, S.A.2
-
10
-
-
80053156423
-
Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer
-
HSU, T., and S. MITRAGOTRI (2011). Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer. Proc. Natl. Acad. Sci. U. S. A. 108, 15816-15821.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A
, vol.108
, pp. 15816-15821
-
-
Hsu, T.1
Mitragotri, S.2
-
11
-
-
74049124186
-
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
-
JACKSON, A. L., and P. S. LINSLEY (2010). Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat. Rev. Drug Discov. 9, 57-67.
-
(2010)
Nat. Rev. Drug Discov
, vol.9
, pp. 57-67
-
-
Jackson, A.L.1
Linsley, P.S.2
-
12
-
-
70349755570
-
Achieving successful delivery of nucleic acids to skin: 6th Annual Meeting of the International Pachyonychia Congenita Consortium
-
KASPAR, R., W. MCLEAN, et al. (2009). Achieving successful delivery of nucleic acids to skin: 6th Annual Meeting of the International Pachyonychia Congenita Consortium. J. Invest. Derm. 129, 2085-2087.
-
(2009)
J. Invest. Derm
, vol.129
, pp. 2085-2087
-
-
Kaspar, R.1
McLean, W.2
-
13
-
-
84859471412
-
Targeting mutant BRAF in melanoma: Current status and future development of combination therapy strategies
-
KUDCHADKAR, R., K. H. PARAISO, et al. (2012). Targeting mutant BRAF in melanoma: current status and future development of combination therapy strategies. Cancer J. 18, 124-131.
-
(2012)
Cancer J
, vol.18
, pp. 124-131
-
-
Kudchadkar, R.1
Paraiso, K.H.2
-
14
-
-
79952741602
-
Mohs surgery for melanoma in situ
-
vii-viii
-
KWON, S. Y., and S. J. MILLER (2011). Mohs surgery for melanoma in situ. Dermatol. Clin. 29, 175-183, vii-viii.
-
(2011)
Dermatol. Clin
, vol.29
, pp. 175-183
-
-
Kwon, S.Y.1
Miller, S.J.2
-
15
-
-
76349084709
-
First-inhuman mutation-targeted siRNA phase 1b trial of an inherited skin disorder
-
LEACHMAN, S. A., R. P. HICKERSON, et al. (2010). First-inhuman mutation-targeted siRNA phase 1b trial of an inherited skin disorder. Mol. Ther. 18, 442-446.
-
(2010)
Mol. Ther
, vol.18
, pp. 442-446
-
-
Leachman, S.A.1
Hickerson, R.P.2
-
16
-
-
72049085243
-
Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals
-
LIN, M. Z., M. R. MCKEOWN, et al. (2009). Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals. Chem. Biol. 16, 1169-1179.
-
(2009)
Chem. Biol
, vol.16
, pp. 1169-1179
-
-
Lin, M.Z.1
McKeown, M.R.2
-
17
-
-
0035710746
-
-ΔΔCT method
-
DOI 10.1006/meth.2001.1262
-
LIVAK, K. J., and T. D. SCHMITTGEN (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402-408. (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
18
-
-
27744590896
-
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
-
DOI 10.1016/j.cell.2005.08.044, PII S0092867405009220
-
MATRANGA, C., Y. TOMARI, et al. (2005). Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123, 607-620. (Pubitemid 41608464)
-
(2005)
Cell
, vol.123
, Issue.4
, pp. 607-620
-
-
Matranga, C.1
Tomari, Y.2
Shin, C.3
Bartel, D.P.4
Zamore, P.D.5
-
19
-
-
84861398281
-
Targeted agents for the treatment of metastatic melanoma
-
MONZON, J. G., and J. DANCEY (2012). Targeted agents for the treatment of metastatic melanoma. Onco. Targets Ther. 5, 31-46.
-
(2012)
Onco. Targets Ther
, vol.5
, pp. 31-46
-
-
Monzon, J.G.1
Dancey, J.2
-
20
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
DOI 10.1038/nature03121
-
SOUTSCHEK, J., A. AKINC, et al. (2004). Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432, 173-178. (Pubitemid 39545841)
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
Elbashir, S.7
Gelck, A.8
Hadwiger, P.9
Harborth, J.10
John, M.11
Kesavan, V.12
Lavine, G.13
Pandey, R.K.14
Racie, T.15
Rajeev, K.S.16
Rohl, I.17
Toudjarska, I.18
Wang, G.19
Wuschko, S.20
Bumcrot, D.21
Kotellansky, V.22
Limmer, S.23
Manoharan, M.24
Vornlocher, H.-P.25
more..
|