POS-1 and GLD-1 repress glp-1 translation through a conserved binding-site cluster

Molecular Biology of the Cell

Volumn 23, Issue 23, 2012, Pages 4473-4483

  Farley, Brian M ^a   Ryder, Sean P ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLD 1 PROTEIN; GLUCAGON LIKE PEPTIDE 1; MESSENGER RNA; POS 1 PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CONTROLLED STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION;

3' UNTRANSLATED REGIONS; ANIMALS; BINDING SITES; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARRIER PROTEINS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM CELLS; GLUCAGON-LIKE PEPTIDE 1; OOGENESIS; REGULATORY SEQUENCES, NUCLEIC ACID; RNA-BINDING PROTEINS; UNTRANSLATED REGIONS;

CAENORHABDITIS ELEGANS;

EID: 84870521307     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-03-0216     Document Type: Article

References (45)

1. Allen MA, Hillier LW, Waterston RH, Blumenthal T (2011). A global analysis of C. elegans trans-splicing. Genome Res 21, 255-264.
2. Austin J, Kimble J (1987). glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell 51, 589-599.
3. Batchelder C, Dunn MA, Choy B, Suh Y, Cassie C, Shim EY, Shin TH, Mello C, Seydoux G, Blackwell TK (1999). Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1. Genes Dev 13, 202-212. (Pubitemid 29061950)
4. Bernstein D, Hook B, Hajarnavis A, Opperman L, Wickens M (2005). Binding specificity and mRNA targets of a C. elegans PUF protein, FBF-1. RNA 11, 447-458. (Pubitemid 40397178)
5. Crittenden SL, Troemel ER, Evans TC, Kimble J (1994). GLP-1 is localized to the mitotic region of the C. elegans germ line. Development 120, 2901-2911. (Pubitemid 24312058)
6. Dsouza M, Larsen N, Overbeek R (1997). Searching for patterns in genomic data. Trends Genet 13, 497-498. (Pubitemid 28004924)
7. Eckmann CR, Crittenden SL, Suh N, Kimble J (2004). GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans. Genetics 168, 147-160. (Pubitemid 39346586)
8. Eckmann CR, Kraemer B, Wickens M, Kimble J (2002). GLD-3, a bicaudal-C homolog that inhibits FBF to control germline sex determination in C. elegans. Dev Cell 3, 697-710. (Pubitemid 35339487)
9. Evans TC, Crittenden SL, Kodoyianni V, Kimble J (1994). Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo. Cell 77, 183-194. (Pubitemid 24138616)
10. Farley BM, Pagano JM, Ryder SP (2008). RNA target specificity of the embryonic cell fate determinant POS-1. RNA 14, 2685-2697.
11. Francis R, Barton MK, Kimble J, Schedl T (1995). gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans. Genetics 139, 579-606.
12. Frand AR, Russel S, Ruvkun G (2005). Functional genomic analysis of C. elegans molting. PLoS Biol 3, e312.
13. Frøkjaer-Jensen C, Davis MW, Hopkins CE, Newman BJ, Thummel JM, Olesen S-P, Grunnet M, Jorgensen EM (2008). Single-copy insertion of transgenes in Caenorhabditis elegans. Nat Genet 40, 1375-1383.
14. Hafner M et al. (2010). Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 141, 129-141.
15. Hansen D, Wilson-Berry L, Dang T, Schedl T (2004). Control of the proliferation versus meiotic development decision in the C. elegans germline through regulation of GLD-1 protein accumulation. Development 131, 93-104. (Pubitemid 38111418)
16. Jadhav S, Rana M, Subramaniam K (2008). Multiple maternal proteins coordinate to restrict the translation of C. elegans nanos-2 to primordial germ cells. Development 135, 1803-1812.
17. Jones AR, Francis R, Schedl T (1996). GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Dev Biol 180, 165-183. (Pubitemid 26426167)
18. Kadyk LC, Kimble J (1998). Genetic regulation of entry into meiosis in Caenorhabditis elegans. Development 125, 1803-1813. (Pubitemid 28274367)
19. Kalchhauser I, Farley BM, Pauli S, Ryder SP, Ciosk R (2011). FBF represses the Cip/Kip cell-cycle inhibitor CKI-2 to promote self-renewal of germline stem cells in C. elegans. EMBO J 30, 3823-3829.
20. Kamath RS, Ahringer J (2003). Genome-wide RNAi screening in Caenorhabditis elegans. Methods 30, 313-321. (Pubitemid 36793968)
21. Kamath RS et al. (2003). Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421, 231-237. (Pubitemid 36139121)
22. Kershner AM, Kimble J (2010). Genome-wide analysis of mRNA targets for Caenorhabditis elegans FBF, a conserved stem cell regulator. Proc Natl Acad Sci USA 107, 3936-3941.
23. Kim KW, Nykamp K, Suh N, Bachorik JL, Wang L, Kimble J (2009). Antagonism between GLD-2 binding partners controls gamete sex. Dev Cell 16, 723-733.
24. Kim KW, Wilson TL, Kimble J (2010). GLD-2/RNP-8 cytoplasmic poly(A) polymerase is a broad-spectrum regulator of the oogenesis program. Proc Natl Acad Sci USA 107, 17445-17450.
25. Lee MH, Schedl T (2001). Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development. Genes Dev 15, 2408-2420.
26. Licatalosi DD et al. (2008). HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature 456, 464-469. (Pubitemid 352759008)
27. Lublin AL, Evans TC (2007). The RNA-binding proteins PUF-5, PUF-6, and PUF-7 reveal multiple systems for maternal mRNA regulation during C. elegans oogenesis. Dev Biol 303, 635-649. (Pubitemid 46350761)
28. Marin VA, Evans TC (2003). Translational repression of a C. elegans Notch mRNA by the STAR/KH domain protein GLD-1. Development 130, 2623-2632. (Pubitemid 37069579)
29. Merritt C, Rasoloson D, Ko D, Seydoux G (2008). 3′ UTRs are the primary regulators of gene expression in the C. elegans germline. Curr Biol 18, 1476-1482.
30. Mickey KM, Mello CC, Montgomery MK, Fire A, Priess JR (1996). An inductive interaction in 4-cell stage C. elegans embryos involves APX-1 expression in the signalling cell. Development 122, 1791-1798. (Pubitemid 26192744)
31. Newport J, Kirschner M (1982). A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription. Cell 30, 687-696. (Pubitemid 13204658)
32. Noble SL, Allen BL, Goh LK, Nordick K, Evans TC (2008). Maternal mRNAs are regulated by diverse P body-related mRNP granules during early Caenorhabditis elegans development. J Cell Biol 182, 559-572.
33. Ogura K-I, Kishimoto N, Mitani S, Gengyo-Ando K, Kohara Y (2003). Translational control of maternal glp-1 mRNA by POS-1 and its interacting protein SPN-4 in Caenorhabditis elegans. Development 130, 2495-2503. (Pubitemid 36722399)
34. Pagano JM, Clingman CC, Ryder SP (2011). Quantitative approaches to monitor protein-nucleic acid interactions using fluorescent probes. RNA 17, 14-20.
35. Pagano JM, Farley BM, Essien KI, Ryder SP (2009). RNA recognition by the embryonic cell fate determinant and germline totipotency factor MEX-3. Proc Natl Acad Sci USA 106, 20252-20257.
36. Reid BG, Flynn GC (1997). Chromophore formation in green fluorescent protein. Biochemistry 36, 6786-6791. (Pubitemid 27242339)
37. Ryder SP, Frater LA, Abramovitz DL, Goodwin EB, Williamson JR (2004). RNA target specificity of the STAR/GSG domain post-transcriptional regulatory protein GLD-1. Nat Struct Mol Biol 11, 20-28. (Pubitemid 38173437)
38. Scheckel C, Gaidatzis D, Wright JE, Ciosk R (2012). Genome-wide analysis of GLD-1-mediated mRNA regulation suggests a role in mRNA storage. PLoS Genet 8, e1002742.
39. Schneider CA, Rasband WS, Eliceiri KW (2012). NIH Image to ImageJ: 25 years of image analysis. Nat Methods 9, 671-675.
40. Suh N, Jedamzik B, Eckmann CR, Wickens M, Kimble J (2006). The GLD-2 poly(A) polymerase activates gld-1 mRNA in the Caenorhabditis elegans germ line. Proc Natl Acad Sci USA 103, 15108-15112. (Pubitemid 44583172)
41. Swanger SA, Bassell GJ (2011). Making and breaking synapses through local mRNA regulation. Curr Opin Genet Dev 21, 414-421.
42. Tabara H, Hill RJ, Mello CC, Priess JR, Kohara Y (1999). pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans. Development 126, 1-11. (Pubitemid 29045895)
43. Tadros W, Lipshitz HD (2009). The maternal-to-zygotic transition: a play in two acts. Development 136, 3033-3042.
44. Wang L, Eckmann CR, Kadyk LC, Wickens M, Kimble J (2002). A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans. Nature 419, 312-316.
45. Wright JE, Gaidatzis D, Senften M, Farley BM, Westhof E, Ryder SP, Ciosk R (2011). A quantitative RNA code for mRNA target selection by the germline fate determinant GLD-1. EMBO J 30, 533-545.