Enhanced intestinal absorption and bioavailability of raloxifene hydrochloride via lyophilized solid lipid nanoparticles

Advanced Powder Technology

Volumn 24, Issue 1, 2013, Pages 393-402

  Burra, Madhu ^a   Jukanti, Raju ^a   Janga, Karthik Yadav ^a   Sunkavalli, Sharath ^a   Velpula, Ashok ^a   Ampati, Srinivas ^a   Jayaveera, K N ^b  

^a ST PETER'S INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

Author keywords

Bioavailability; Perfusion; Raloxifene HCl; Solid lipid nanoparticles; Tristearin

Indexed keywords

BIOAVAILABILITY; PERFUSION; RALOXIFENE HCL; SOLID LIPID NANOPARTICLE (SLN); TRISTEARIN;

NANOPARTICLES; ZETA POTENTIAL;

BIOCHEMISTRY;

EID: 84870515210     PISSN: 09218831     EISSN: 15685527     Source Type: Journal    
DOI: 10.1016/j.apt.2012.09.002     Document Type: Article

References (38)

1. R. Lobenberg, and G.L. Amidon Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards Eur. J. Pharm. Biopharm. 50 2000 3 12
2. J.C. Chaumeil Micronization: a method of improving the bioavailability of poorly soluble drugs Methods Find, Exp. Clin. Pharmacol. 20 1998 211 215
3. S.G. Kapsi, and J.W. Ayres Processing factors in development of solid solution formulation of itraconazole for enhancement of drug dissolution and bioavailability Int. J. Pharm. 229 2001 193 203
4. F. Veiga, C. Fernandes, and P. Maincent Influence of the preparation method on the physicochemical properties of tolbutamide/cyclodextrin binary systems Drug Dev. Ind. Pharm. 27 2001 523 532
5. T.L. Rogers, J. Hu, Z. Yu, K.P. Johnston, and R.O. Williams III A novel particle engineering technology: spray freezing into liquid Int. J. Pharm. 242 2002 93 100
6. W.N. Charman, C.J.H. Porter, S. Mithani, and J.B. Dressman Physicochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH J. Pharm. Sci. 86 1997 269 282
7. V.H. Sunesen, R. Vedesdal, H.G. Kristensen, L. Christrup, and A. Mullertz Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug Eur. J. Pharm. Sci. 24 2005 297 303
8. C.W. Pouton Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system Eur. J. Pharm. Sci. 29 2006 278 287
9. C.J.H. Porter, N.L. Trevaskis, and W.N. Charman Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs Nat. Rev. Drug Discov. 6 2007 231 248
10. R.H. Muller, K. Mader, and S. Gohla Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art Eur. J. Pharm. Biopharm. 50 2000 161 177
11. C.J.H. Porter, and W.N. Charman Intestinal lymphatic drug transport: an update Adv. Drug Deliv. Rev. 50 2001 61 80
12. B.H. Mitlak, and F.J. Cohen In search of optimal long term female hormone replacement: the potential of selective estrogen receptor modulators Horm. Res. 48 1997 155 163
13. F.W. Michael, V.J. Wacher, K.M. Ruble, M.G. Ramsey, K.J. Edgar, and N.L. Buchanan Pharmacokinetics of raloxifene in male Wistar-Hannover rats: influence of complexation with hydroxybutenyl-beta-cyclodextrin Int. J. Pharm. 346 2008 25 37
14. B. Jagadish, R. Yelchuri, K. Bindu, H. Tangi, S. Maroju, and V.U. Rao Enhanced dissolution and bioavailability of raloxifene hydro-bioavailability enhancement of raloxifene hydrochloride chloride by co-grinding with different superdisintegrants Chem. Pharm. Bull. 58 2010 293 300
15. R.K. Jha, S. Tiwari, and B. Mishra1 Bioadhesive microspheres for bioavailability enhancement of raloxifene hydrochloride: formulation and pharmacokinetic evaluation AAPS PharmSciTech. 2011 10.1208/s12249-011-9619-9
16. K. Manjunath, and V. Venkateswarlu Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles J. Control. Rel. 95 2004 627 638
17. V.V. Kumar, D. Chandrasekar, S. Ramakrishna, V. Kishan, Y.M. Rao, and P.V. Diwan Development and evaluation of nitrendipine loaded solid lipid nanoparticles: influence of wax and glyceride lipids on plasma pharmacokinetics Int. J. Pharm. 335 2007 167 175
18. R. Jukanti, G. Devaraj, R. Devaraj, and S. Apte Drug targeting to inflammation: studies on antioxidant surface loaded diclofenac liposomes Int. J. Pharm. 414 2011 279 285
19. R. Jukanti, S. Sheela, S. Bandari, and P.R. Veerareddy Enhanced bioavailability of exemestane via proliposomes based transdermal delivery J. Pharm. Sci. 100 2011 3208 3222
20. V. Teeranachaideekul, E.B. Souto, R.H. Müller, and V.B. Junyaprasert Physicochemical characterization and in vitro release studies of ascorbylpalmitate-loaded semi-solid nanostructured lipid carriers (NLC gels) J. Microencapsul. 25 2008 111 120
21. P. Zakeri-Milani, H. Valizadeh, H. Tajerzadeh, Y. Azarmi, Z. Islambolchilar, and S. Barzegara Predicting human intestinal permeability using single-pass intestinal perfusion in rat J. Pharm. Pharm. Sci. 10 2007 368 379
22. K. Westesen, Particles with Modified Physico-Chemical Properties, their Preparation and Uses, US Patent No. 6197349, 2000.
23. M.R. Gasco, Method for Producing Solid Lipid Microspheresc Having Narrow Size Distribution, US Patent 5 (1993) 250,236.
24. R.H. Muller, W. Mehenert, J.S. Lucks, A. Schwarz, M.H. Zur, and C. Weyhers Solid lipid nanoparticles (SLN) - an alternative colloidal carrier system for controlled drug delivery Eur. J. Pharm. Biopharm. 41 1995 62 69
25. A. Dingler, and S. Gohla Production of solid lipid nanoparticles (SLN): scaling up feasibilities J. Microencapsul. 19 2002 11 16
26. F.Q. Hu, H. Yuan, H.H. Zhang, and M. Fang Preparation of solid lipid nanoparticles with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization Int. J. Pharm. 239 2002 121 128
27. W. Mehnert, and K. Mader Solid lipid nanoparticles production, characterization and applications Adv. Drug Deliv. Rev. 47 2001 165 196
28. M.A. Schubert, and C.C. Muller-Goymann Characterisation of surface modified solid lipid nanoparticles (SLN): influence of lecithin and nonionic emulsifier Eur. J. Pharm. Biopharm. 61 2005 77 86
29. R.P. Thatipamula, C.R. Palem, R. Gannu, S. Mudragada, and M.R. Yamsani Formulation and in vitro characterization of domperidone loaded solid lipid nanoparticles and nanostructured lipid carriers Daru 19 2011 23 32
30. B.G. Muller, H. Leuenberger, and T. Kissel Albumin nanospheres as carriers for passive drug targeting: an optimized manufacturing technique Pharm. Res. 13 1996 32 37
31. M.K. Rawat, A. Jain, and S. Singh Studies on binary lipid matrix based solid lipid nanoparticles of repaglinide: in vitro and in vivo evaluation J. Pharm. Sci. 100 2011 2366 2378
32. A.Z. Muhlen, C. Schwarz, and W. Mehnert Solid lipid nanoparticles (SLN) for controlled release drug delivery - drug release and release mechanism Eur. J. Pharm. Biopharm. 45 1998 149 155
33. M.J. Pikal, S. Shah, M.L. Roy, and R. Putman The secondary drying stage of freeze drying: drying kinetics as a function of temperature and chamber pressure Int. J. Pharm. 60 1990 203 217
34. W.C. Mobley, and H. Schreier Phase transition temperature reduction and glass transformation in dehydroprotected lyophilized liposomes J. Control. Rel. 31 1994 73 87
35. Y. Ishigami, and H. Machida Vesicles from sucrose fatty acid esters JOACS 66 1989 599 603
36. K. Westesen, B. Siekmann, and M.H.J. Koch Investigations on the physical state of lipid nanoparticles by synchrotron radiation X-ray diffraction Int. J. Pharm. 93 1993 189 199
37. B.D. Rege, J.P. Kao, and J.E. Polli Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers Eur. J. Pharm. Sci. 16 2002 237 246
38. Y. Luo, D. Chen, L. Ren, X. Zhao, and J. Qin Solid lipid nanoparticles for enhancing vinpocetine's oral bioavailability J. Control. Rel. 114 2006 53 59