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Volumn 56, Issue 6, 2012, Pages 2094-2105

Hepatitis c virus-specific t-cell-derived transforming growth factor beta is associated with slow hepatic fibrogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CORE PROTEIN; GAMMA INTERFERON; INTERLEUKIN 10; TRANSFORMING GROWTH FACTOR BETA;

EID: 84870514165     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25951     Document Type: Article
Times cited : (23)

References (37)
  • 1
    • 40049097359 scopus 로고    scopus 로고
    • Liver cirrhosis
    • Schuppan D, Afdhal NH. Liver cirrhosis. Lancet 2008; 371: 838-851.
    • (2008) Lancet , vol.371 , pp. 838-851
    • Schuppan, D.1    Afdhal, N.H.2
  • 2
    • 75149163334 scopus 로고    scopus 로고
    • Aging of hepatitis C virus (HCV)-infected persons in the United States: a multiple cohort model of HCV prevalence and disease progression
    • 521 e511-516.
    • Davis GL, Alter MJ, El-Serag H, Poynard T, Jennings LW. Aging of hepatitis C virus (HCV)-infected persons in the United States: a multiple cohort model of HCV prevalence and disease progression. Gastroenterology 2010; 138: 513-521, 521 e511-516.
    • (2010) Gastroenterology , vol.138 , pp. 513-521
    • Davis, G.L.1    Alter, M.J.2    El-Serag, H.3    Poynard, T.4    Jennings, L.W.5
  • 4
    • 10244225383 scopus 로고    scopus 로고
    • Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response
    • Missale G, Bertoni R, Lamonaca V, Valli A, Massari M, Mori C, et al. Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. J Clin Invest 1996; 98: 706-714.
    • (1996) J Clin Invest , vol.98 , pp. 706-714
    • Missale, G.1    Bertoni, R.2    Lamonaca, V.3    Valli, A.4    Massari, M.5    Mori, C.6
  • 5
    • 9244255343 scopus 로고    scopus 로고
    • Cell-mediated immunity and the outcome of hepatitis C virus infection
    • Shoukry NH, Cawthon AG, Walker CM. Cell-mediated immunity and the outcome of hepatitis C virus infection. Annu Rev Microbiol 2004; 58: 391-424.
    • (2004) Annu Rev Microbiol , vol.58 , pp. 391-424
    • Shoukry, N.H.1    Cawthon, A.G.2    Walker, C.M.3
  • 6
    • 0037105567 scopus 로고    scopus 로고
    • Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
    • Wedemeyer H, He XS, Nascimbeni M, Davis AR, Greenberg HB, Hoofnagle JH, et al. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J Immunol 2002; 169: 3447-3458.
    • (2002) J Immunol , vol.169 , pp. 3447-3458
    • Wedemeyer, H.1    He, X.S.2    Nascimbeni, M.3    Davis, A.R.4    Greenberg, H.B.5    Hoofnagle, J.H.6
  • 7
    • 0034858270 scopus 로고    scopus 로고
    • Direct ex vivo comparison of the breadth and specificity of the T cells in the liver and peripheral blood of patients with chronic HCV infection
    • Grabowska AM, Lechner F, Klenerman P, Tighe PJ, Ryder S, Ball JK, et al. Direct ex vivo comparison of the breadth and specificity of the T cells in the liver and peripheral blood of patients with chronic HCV infection. Eur J Immunol 2001; 31: 2388-2394.
    • (2001) Eur J Immunol , vol.31 , pp. 2388-2394
    • Grabowska, A.M.1    Lechner, F.2    Klenerman, P.3    Tighe, P.J.4    Ryder, S.5    Ball, J.K.6
  • 8
    • 13044313467 scopus 로고    scopus 로고
    • Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers
    • He XS, Rehermann B, Lopez-Labrador FX, Boisvert J, Cheung R, Mumm J, et al. Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers. Proc Natl Acad Sci U S A 1999; 96: 5692-5697.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5692-5697
    • He, X.S.1    Rehermann, B.2    Lopez-Labrador, F.X.3    Boisvert, J.4    Cheung, R.5    Mumm, J.6
  • 9
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: more questions than answers
    • Shevach EM. CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2002; 2: 389-400.
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 10
    • 0036467522 scopus 로고    scopus 로고
    • CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
    • Kingsley CI, Karim M, Bushell AR, Wood KJ. CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J Immunol 2002; 168: 1080-1086.
    • (2002) J Immunol , vol.168 , pp. 1080-1086
    • Kingsley, C.I.1    Karim, M.2    Bushell, A.R.3    Wood, K.J.4
  • 11
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003; 4: 330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 12
    • 33846283803 scopus 로고    scopus 로고
    • Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells
    • Hartigan-O'Connor DJ, Poon C, Sinclair E, McCune JM. Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells. J Immunol Methods 2007; 319: 41-52.
    • (2007) J Immunol Methods , vol.319 , pp. 41-52
    • Hartigan-O'Connor, D.J.1    Poon, C.2    Sinclair, E.3    McCune, J.M.4
  • 15
    • 19944370822 scopus 로고    scopus 로고
    • T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection
    • Boettler T, Spangenberg HC, Neumann-Haefelin C, Panther E, Urbani S, Ferrari C, et al. T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. J Virol 2005; 79: 7860-7867.
    • (2005) J Virol , vol.79 , pp. 7860-7867
    • Boettler, T.1    Spangenberg, H.C.2    Neumann-Haefelin, C.3    Panther, E.4    Urbani, S.5    Ferrari, C.6
  • 16
    • 19944366276 scopus 로고    scopus 로고
    • Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection
    • Rushbrook SM, Ward SM, Unitt E, Vowler SL, Lucas M, Klenerman P, et al. Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection. J Virol 2005; 79: 7852-7859.
    • (2005) J Virol , vol.79 , pp. 7852-7859
    • Rushbrook, S.M.1    Ward, S.M.2    Unitt, E.3    Vowler, S.L.4    Lucas, M.5    Klenerman, P.6
  • 17
    • 34547604820 scopus 로고    scopus 로고
    • Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection
    • Ward SM, Fox BC, Brown PJ, Worthington J, Fox SB, Chapman RW, et al. Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection. J Hepatol 2007; 47: 316-324.
    • (2007) J Hepatol , vol.47 , pp. 316-324
    • Ward, S.M.1    Fox, B.C.2    Brown, P.J.3    Worthington, J.4    Fox, S.B.5    Chapman, R.W.6
  • 18
    • 77249118149 scopus 로고    scopus 로고
    • Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis
    • Claassen MA, de Knegt RJ, Tilanus HW, Janssen HL, Boonstra A. Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis. J Hepatol 2010; 52: 315-321.
    • (2010) J Hepatol , vol.52 , pp. 315-321
    • Claassen, M.A.1    de Knegt, R.J.2    Tilanus, H.W.3    Janssen, H.L.4    Boonstra, A.5
  • 19
    • 43249107955 scopus 로고    scopus 로고
    • Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection
    • Ebinuma H, Nakamoto N, Li Y, Price DA, Gostick E, Levine BL, et al. Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection. J Virol 2008; 82: 5043-5053.
    • (2008) J Virol , vol.82 , pp. 5043-5053
    • Ebinuma, H.1    Nakamoto, N.2    Li, Y.3    Price, D.A.4    Gostick, E.5    Levine, B.L.6
  • 20
    • 0037086525 scopus 로고    scopus 로고
    • CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons
    • MacDonald AJ, Duffy M, Brady MT, McKiernan S, Hall W, Hegarty J, et al. CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J Infect Dis 2002; 185: 720-727.
    • (2002) J Infect Dis , vol.185 , pp. 720-727
    • MacDonald, A.J.1    Duffy, M.2    Brady, M.T.3    McKiernan, S.4    Hall, W.5    Hegarty, J.6
  • 21
    • 0141755413 scopus 로고    scopus 로고
    • Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect
    • Nelson DR, Tu Z, Soldevila-Pico C, Abdelmalek M, Zhu H, Xu YL, et al. Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect. HEPATOLOGY 2003; 38: 859-868.
    • (2003) HEPATOLOGY , vol.38 , pp. 859-868
    • Nelson, D.R.1    Tu, Z.2    Soldevila-Pico, C.3    Abdelmalek, M.4    Zhu, H.5    Xu, Y.L.6
  • 22
    • 33645857965 scopus 로고    scopus 로고
    • Increased hepatitis C virus (HCV)-specific CD4+CD25+ regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels
    • Bolacchi F, Sinistro A, Ciaprini C, Demin F, Capozzi M, Carducci FC, et al. Increased hepatitis C virus (HCV)-specific CD4+CD25+ regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels. Clin Exp Immunol 2006; 144: 188-196.
    • (2006) Clin Exp Immunol , vol.144 , pp. 188-196
    • Bolacchi, F.1    Sinistro, A.2    Ciaprini, C.3    Demin, F.4    Capozzi, M.5    Carducci, F.C.6
  • 23
    • 2142702915 scopus 로고    scopus 로고
    • Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection
    • Accapezzato D, Francavilla V, Paroli M, Casciaro M, Chircu LV, Cividini A, et al. Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection. J Clin Invest 2004; 113: 963-972.
    • (2004) J Clin Invest , vol.113 , pp. 963-972
    • Accapezzato, D.1    Francavilla, V.2    Paroli, M.3    Casciaro, M.4    Chircu, L.V.5    Cividini, A.6
  • 24
    • 33845650186 scopus 로고    scopus 로고
    • Intrahepatic virus-specific IL-10-producing CD8 T cells prevent liver damage during chronic hepatitis C virus infection
    • Abel M, Sene D, Pol S, Bourliere M, Poynard T, Charlotte F, et al. Intrahepatic virus-specific IL-10-producing CD8 T cells prevent liver damage during chronic hepatitis C virus infection. HEPATOLOGY 2006; 44: 1607-1616.
    • (2006) HEPATOLOGY , vol.44 , pp. 1607-1616
    • Abel, M.1    Sene, D.2    Pol, S.3    Bourliere, M.4    Poynard, T.5    Charlotte, F.6
  • 25
    • 34249787349 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCV-specific T-cell responses
    • Alatrakchi N, Graham CS, van der Vliet HJ, Sherman KE, Exley MA, Koziel MJ. Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCV-specific T-cell responses. J Virol 2007; 81: 5882-5892.
    • (2007) J Virol , vol.81 , pp. 5882-5892
    • Alatrakchi, N.1    Graham, C.S.2    van der Vliet, H.J.3    Sherman, K.E.4    Exley, M.A.5    Koziel, M.J.6
  • 26
    • 33846086980 scopus 로고    scopus 로고
    • Transforming growth factor-beta: innately bipolar
    • Wahl SM. Transforming growth factor-beta: innately bipolar. Curr Opin Immunol 2007; 19: 55-62.
    • (2007) Curr Opin Immunol , vol.19 , pp. 55-62
    • Wahl, S.M.1
  • 28
    • 13944257273 scopus 로고    scopus 로고
    • CD8+ cell responses to hepatitis C virus (HCV) in the liver of persons with HCV-HIV coinfection versus HCV monoinfection
    • Alatrakchi N, Graham CS, He Q, Sherman KE, Koziel MJ. CD8+ cell responses to hepatitis C virus (HCV) in the liver of persons with HCV-HIV coinfection versus HCV monoinfection. J Infect Dis 2005; 191: 702-709.
    • (2005) J Infect Dis , vol.191 , pp. 702-709
    • Alatrakchi, N.1    Graham, C.S.2    He, Q.3    Sherman, K.E.4    Koziel, M.J.5
  • 29
    • 34447523803 scopus 로고    scopus 로고
    • T cell dysfunction by hepatitis C virus core protein involves PD-1/PDL-1 signaling
    • Yao ZQ, King E, Prayther D, Yin D, Moorman J. T cell dysfunction by hepatitis C virus core protein involves PD-1/PDL-1 signaling. Viral Immunol 2007; 20: 276-287.
    • (2007) Viral Immunol , vol.20 , pp. 276-287
    • Yao, Z.Q.1    King, E.2    Prayther, D.3    Yin, D.4    Moorman, J.5
  • 30
    • 10844242987 scopus 로고    scopus 로고
    • Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
    • Xu L, Hui AY, Albanis E, Arthur MJ, O'Byrne SM, Blaner WS, et al. Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut 2005; 54: 142-151.
    • (2005) Gut , vol.54 , pp. 142-151
    • Xu, L.1    Hui, A.Y.2    Albanis, E.3    Arthur, M.J.4    O'Byrne, S.M.5    Blaner, W.S.6
  • 32
    • 0142219250 scopus 로고    scopus 로고
    • Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis
    • Kitani A, Fuss I, Nakamura K, Kumaki F, Usui T, Strober W. Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis. J Exp Med 2003; 198: 1179-1188.
    • (2003) J Exp Med , vol.198 , pp. 1179-1188
    • Kitani, A.1    Fuss, I.2    Nakamura, K.3    Kumaki, F.4    Usui, T.5    Strober, W.6
  • 35
    • 46749138596 scopus 로고    scopus 로고
    • Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
    • Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP, et al. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 2008; 29: 44-56.
    • (2008) Immunity , vol.29 , pp. 44-56
    • Yang, X.O.1    Nurieva, R.2    Martinez, G.J.3    Kang, H.S.4    Chung, Y.5    Pappu, B.P.6
  • 36
    • 61449152973 scopus 로고    scopus 로고
    • Regulatory T cells and viral liver disease
    • Alatrakchi N, Koziel M. Regulatory T cells and viral liver disease. J Viral Hepat 2009; 16: 223-229.
    • (2009) J Viral Hepat , vol.16 , pp. 223-229
    • Alatrakchi, N.1    Koziel, M.2
  • 37
    • 84861199609 scopus 로고    scopus 로고
    • Lack of TGF-β production by hepatitis C virus-specific T cells during HCV acute phase is associated with HCV clearance in HIV coinfection
    • Harfouch S, Guiguet M, Valantin MA, Samri A, Ouazene Z, Slama L, et al. Lack of TGF-β production by hepatitis C virus-specific T cells during HCV acute phase is associated with HCV clearance in HIV coinfection. J Hepatol 2012; 56: 1259-1268.
    • (2012) J Hepatol , vol.56 , pp. 1259-1268
    • Harfouch, S.1    Guiguet, M.2    Valantin, M.A.3    Samri, A.4    Ouazene, Z.5    Slama, L.6


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