Umbelliprenin is cytotoxic against QU-DB large cell lung cancer cell line but anti-proliferative against A549 adenocarcinoma cells

DARU, Journal of Pharmaceutical Sciences

Volumn 20, Issue 1, 2012, Pages

  Khaghanzadeh, Narges ^a,b   Mojtahedi, Zahra ^a   Ramezani, Mohammad ^c   Erfani, Nasrollah ^a   Ghaderi, Abbas ^a,b  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Annexin; IC50; Lung cancer; MTT assay; Propidium Iodide; Umbelliprenin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; COUMARIN DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; PROPIDIUM IODIDE; UMBELLIPRENIN; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; LUNG ADENOCARCINOMA;

EID: 84870512215     PISSN: 15608115     EISSN: 20082231     Source Type: Journal    
DOI: 10.1186/2008-2231-20-69     Document Type: Article

References (26)

1. Chemotherapy of advanced non-small cell lung cancer. Pirker R, Minar W, Front Radiat Ther Oncol 2010 42 157 163 19955802
2. Cancer incidence in southern Iran, 1998-2002: Results of population-based cancer registry. Masoompour SM, Yarmohammadi H, Rezaianzadeh A, Lankarani KB, Cancer Epidemiol 2011 35 42 e47 10.1016/j.canep.2011.05.018 21840285
3. EGFR targeted therapy in non-small cell lung cancer: potential role of cetuximab. Reade CA, Ganti AK, Biologics 2009 3 215 224 19707410
4. Worldwide trends in lung cancer pathology. Gabrielson E, Respirology 2006 11 533 538 10.1111/j.1440-1843.2006.00909.x 16916324 (Pubitemid 44186257)
5. Therapeutic options for elderly patients with advanced non-small cell lung cancer. Avery EJ, Kessinger A, Ganti AK, Cancer Treat Rev 2009 35 340 344 10.1016/j.ctrv.2008.10.008 19155139
6. The current status of targeted therapy for Non-small cell lung cancer. Francis H, Solomon B, Intern Med J 2010 40 611 618 10.1111/j.1445-5994.2009. 02141.x 20002849
7. New sesquiterpene coumarins from the roots of Ferula flabelliloba. Iranshahi M, Kalategi F, Sahebkar A, Sardashti A, Schneider B, Pharm Biol 2003 41 431 433 10.1076/phbi.41.6.431.17834 (Pubitemid 37468122)
8. Auraptene: a natural biologically active compound with multiple targets. Genovese S, Epifano F, Curr Drug Targets 2011 12 381 386 10.2174/ 138945011794815248 20955144
9. Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented malignant melanoma cells through cell-cycle arrest in G1 and induction of caspase-dependent apoptosis. Barthomeuf C, Lim S, Iranshahi M, Chollet P, Phytomedicine 2008 15 103 111 10.1016/j.phymed.2007.04.001 17689942
10. Cancer chemopreventive activity of the prenylated coumarin, umbelliprenin, in vivo. Iranshahi M, Sahebkar A, Takasaki M, Konoshima T, Tokuda H, Eur J Cancer Prev 2009 18 412 415 10.1097/CEJ.0b013e32832c389e 19531956
11. Two matrix metalloproteinases inhibitors from Ferula persica var. persica. Shahverdi AR, Saadat F, Khorramizadeh MR, Iranshahi M, Khoshayand MR, Phytomedicine 2006 13 712 717 10.1016/j.phymed.2006.01.003 16487689 (Pubitemid 44666401)
12. Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic. Stetler-Stevenson WG, Hewitt R, Corcoran M, Semin Cancer Biol 1996 7 147 154 10.1006/scbi.1996.0020 8773300 (Pubitemid 26179261)
13. The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis. John A, Tuszynski G, Pathol Oncol Res 2001 7 14 23 10.1007/BF03032599 11349215 (Pubitemid 32591662)
14. Evaluation of antigenotoxicity effects of umbelliprenin on human peripheral lymphocytes exposed to oxidative stress. Soltani F, Mosaffa F, Iranshahi M, Karimi G, Malekaneh M, Haghighi F, Behravan J, Cell Biol Toxicol 2009 25 291 296 10.1007/s10565-008-9083-9 18618275
15. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Mosmann T, J Immunol Methods 1983 65 55 63 10.1016/0022-1759(83)90303-4 6606682 (Pubitemid 14203433)
16. Differential role of hydrogen peroxide and staurosporine in induction of cell death in glioblastoma cells lacking DNA-dependent protein kinase. Chen GG, Sin FL, Leung BC, Ng HK, Poon WS, Apoptosis 2005 10 185 192 10.1007/s10495-005- 6073-8 15711934 (Pubitemid 40558126)
17. Synthesis and Purification of 7-Prenyloxycoumarins and Herniarin as Bioactive Natural Coumarins. Askari M, Sahebkar A, Iranshahi M, Iranian Journal of Basic Medical Sciences 2009 12 63 69
18. Anti-tumor effects of bakuchiol, an analogue of resveratrol, on human lung adenocarcinoma A549 cell line. Chen Z, Jin K, Gao L, Lou G, Jin Y, Yu Y, Lou Y, Eur J Pharmacol 2010 643 170 179 10.1016/j.ejphar.2010.06.025 20599920
19. Apoptosis can be detected in attached colonic adenocarcinoma HT29 cells using annexin V binding, but not by TUNEL assay or sub-G0 DNA content. Clarke R, Lund E, Johnson II, Pinder A, Cytometry 2000 40 252 10.1002/1097-0320(20000701) 40:3<252::AID-CYTO12>3.0.CO;2-7 10878570
20. Induction of apoptosis in human corneal epithelial cells in vitro. Kim JM, Stapleton F, Willcox MD, Aust N Z J Ophthalmol 1999 27 214 217 10.1046/j.1440-1606.1999.00210.x 10484195 (Pubitemid 29429690)
21. Establishment of a human large cell lung tumor line (QU-DB) with metastatic properties in athymic mice. Cole SP, Campling BG, Dexter DF, Holden JJ, Roder JC, Cancer 1986 58 917 923 10.1002/1097-0142(19860815)58:4<917:: AID-CNCR2820580419>3.0.CO;2-0 3719556 (Pubitemid 16035293)
22. Characterization of anticancer agents by their growth inhibitory activity and relationships to mechanism of action and structure. Keskin O, Bahar I, Jernigan RL, Beutler JA, Shoemaker RH, Sausville EA, Covell DG, Anticancer Drug Des 2000 15 79 98 10901296 (Pubitemid 30410467)
23. 7-Diethylamino-3(2'-benzoxazolyl)-coumarin is a novel microtubule inhibitor with antimitotic activity in multidrug resistant cancer cells. Kim SN, Kim NH, Park YS, Kim H, Lee S, Wang Q, Kim YK, Biochem Pharmacol 2009 77 1773 1779 10.1016/j.bcp.2009.03.007 19428332
24. Apoptogenic effect of 7,8-diacetoxy-4-methylcoumarin and 7,8-diacetoxy-4-methylthiocoumarin in human lung adenocarcinoma cell line: role of NF-kappaB, Akt, ROS and MAP kinase pathway. Goel A, Prasad AK, Parmar VS, Ghosh B, Saini N, Chem Biol Interact 2009 179 363 374 10.1016/j.cbi.2008.10.060 19061872
25. Evaluation of antioxidant, anti-inflammatory and lipoxygenase inhibitory activities of the prenylated coumarin umbelliprenin. Iranshahi M, Askari M, Sahebkar A, Hadjipavlou-Litina D, DARU 2009 17 99 103
26. Apoptosis: a review of programmed cell death. Elmore S, Toxicol Pathol 2007 35 495 516 10.1080/01926230701320337 17562483 (Pubitemid 46911891)