Apoptosis induction by OTA and TNF-α in cultured primary rat hepatocytes and prevention by silibinin

Toxins

Volumn 4, Issue 11, 2012, Pages 1139-1156

  Essid, Ebtisam ^a   Dernawi, Yousef ^a   Petzinger, Ernst ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Apoptosis; Caspase 3; DNA ladder; Hydrogen peroxide; Malondialdehyde; Ochratoxin A; Rat hepatocytes; Silibinin; Tumor necrosis factor alpha; UV C light

Indexed keywords

CASPASE 3; DACTINOMYCIN; DNA; DNA FRAGMENT; HYDROGEN PEROXIDE; MALONALDEHYDE; OCHRATOXIN; SILIBININ; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR ALPHA RECEPTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL ASSAY; CELL IMMORTALIZATION; CELL PROTECTION; CELL STIMULATION; CELL VIABILITY; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; DRUG MECHANISM; ENZYME ACTIVATION; IN VITRO STUDY; INCUBATION TIME; LIPID PEROXIDATION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; SUPERNATANT; ULTRAVIOLET C RADIATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; CHROMATIN; DACTINOMYCIN; DNA FRAGMENTATION; HEPATOCYTES; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; OCHRATOXINS; OXIDATIVE STRESS; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SILYMARIN; TUMOR NECROSIS FACTOR-ALPHA; ULTRAVIOLET RAYS;

RATTUS;

EID: 84870497742     PISSN: 20726651     EISSN: None     Source Type: Journal    
DOI: 10.3390/toxins4111139     Document Type: Article

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