Sustained release from hot-melt extruded matrices based on ethylene vinyl acetate and polyethylene oxide

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 3, 2012, Pages 526-533

  Almeida, A ^a   Brabant, L ^a   Siepmann, F ^b   De Beer, T ^a   Bouquet, W ^a   Van Hoorebeke, L ^a   Siepmann, J ^b   Remon, J P ^a   Vervaet, C ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIV LILLE   (France)

Author keywords

Ethylene vinyl acetate; Hot melt extrusion; Polyethylene oxide; Sustained release

Indexed keywords

ETHYLENE VINYL ACETATE COPOLYMER; MACROGOL; METOPROLOL TARTRATE;

ARTICLE; BIOAVAILABILITY; DRUG FORMULATION; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; MATHEMATICAL MODEL; MISCIBILITY; MOLECULAR WEIGHT; MORPHOLOGY; PELLET EXTRUSION; POROSITY; RAMAN SPECTROMETRY; RIGIDITY; SOLID STATE; SUSTAINED DRUG RELEASE; TEMPERATURE; TOMOGRAPHY; VISCOSITY; X RAY;

ANIMALS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; DOGS; DRUG CARRIERS; DRUG COMPOUNDING; HOT TEMPERATURE; MALE; METOPROLOL; MODELS, THEORETICAL; POLYETHYLENE GLYCOLS; POLYVINYLS; POROSITY; SPECTRUM ANALYSIS, RAMAN; TOMOGRAPHY, X-RAY; VISCOSITY;

EID: 84870489756     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.08.008     Document Type: Article

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