-
1
-
-
0043210670
-
FDA drug approval summary: gefitinib (ZD1839) (Iressa) tablets
-
Cohen MH, Williams GA, Sridhara R, Chen G, Pazdur R. FDA drug approval summary: gefitinib (ZD1839) (Iressa) tablets. Oncologist 2003; 8: 303-306.
-
(2003)
Oncologist
, vol.8
, pp. 303-306
-
-
Cohen, M.H.1
Williams, G.A.2
Sridhara, R.3
Chen, G.4
Pazdur, R.5
-
2
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011; 364: 2507-2516.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
-
3
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344: 783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
-
4
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri GD, Mehren von M, Blanke CD, Van den Abbeele AD, Eisenberg B, Roberts PJ, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002; 347: 472-480.
-
(2002)
N Engl J Med
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
Mehren von, M.2
Blanke, C.D.3
Van den Abbeele, A.D.4
Eisenberg, B.5
Roberts, P.J.6
-
5
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang Y-J, Camidge DR, Shaw AT, Solomon B, Maki RG, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010; 363: 1693-1703.
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.-J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
Maki, R.G.6
-
6
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, O'Callaghan CJ, Tu D, Tebbutt NC, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008; 359: 1757-1765.
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
O'Callaghan, C.J.4
Tu, D.5
Tebbutt, N.C.6
-
7
-
-
0037025173
-
Cancer. Addiction to oncogenes-the Achilles heal of cancer
-
Weinstein IB. Cancer. Addiction to oncogenes-the Achilles heal of cancer. Science 2002; 297: 63-64.
-
(2002)
Science
, vol.297
, pp. 63-64
-
-
Weinstein, I.B.1
-
8
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc J-F, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-390.
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.-F.6
-
9
-
-
84859880607
-
Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma
-
Llovet JM, Pena CEA, Lathia CD, Shan M, Meinhardt G, Bruix J, et al. Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma. Clin Cancer Res 2012; 18: 2290-2300.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2290-2300
-
-
Llovet, J.M.1
Pena, C.E.A.2
Lathia, C.D.3
Shan, M.4
Meinhardt, G.5
Bruix, J.6
-
10
-
-
79955433548
-
Targeted therapies for hepatocellular carcinoma
-
Villanueva A, Llovet JM. Targeted therapies for hepatocellular carcinoma. Gastroenterology 2011; 140: 1410-1426.
-
(2011)
Gastroenterology
, vol.140
, pp. 1410-1426
-
-
Villanueva, A.1
Llovet, J.M.2
-
11
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell PC. The clonal evolution of tumor cell populations. Science 1976; 194: 23-28.
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
12
-
-
77958014613
-
How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine
-
Gerlinger M, Swanton C. How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine. Br J Cancer 2010; 103: 1139-1143.
-
(2010)
Br J Cancer
, vol.103
, pp. 1139-1143
-
-
Gerlinger, M.1
Swanton, C.2
-
13
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010; 467: 1114-1117.
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
Antal, T.4
Leary, R.5
Fu, B.6
-
14
-
-
78049380554
-
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
-
Campbell PJ, Yachida S, Mudie LJ, Stephens PJ, Pleasance ED, Stebbings LA, et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 2010; 467: 1109-1113.
-
(2010)
Nature
, vol.467
, pp. 1109-1113
-
-
Campbell, P.J.1
Yachida, S.2
Mudie, L.J.3
Stephens, P.J.4
Pleasance, E.D.5
Stebbings, L.A.6
-
15
-
-
84856082746
-
Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies
-
Haeno H, Gonen M, Davis MB, Herman JM, Iacobuzio-Donahue CA, Michor F. Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies. Cell 2012; 148: 362-375.
-
(2012)
Cell
, vol.148
, pp. 362-375
-
-
Haeno, H.1
Gonen, M.2
Davis, M.B.3
Herman, J.M.4
Iacobuzio-Donahue, C.A.5
Michor, F.6
-
16
-
-
84983720414
-
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data
-
Tao Y, Ruan J, Yeh S-H, Lu X, Wang Y, Zhai W, et al. Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A 2011; 108: 12042-12047.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 12042-12047
-
-
Tao, Y.1
Ruan, J.2
Yeh, S.-H.3
Lu, X.4
Wang, Y.5
Zhai, W.6
-
17
-
-
84859717053
-
Cell population genetics and deep sequencing: a novel approach for drivers discovery in hepatocellular carcinoma
-
Alsinet C, Villanueva A, Llovet JM. Cell population genetics and deep sequencing: a novel approach for drivers discovery in hepatocellular carcinoma. J Hepatol 2012; 56: 1198-1200.
-
(2012)
J Hepatol
, vol.56
, pp. 1198-1200
-
-
Alsinet, C.1
Villanueva, A.2
Llovet, J.M.3
-
18
-
-
79952231921
-
Management of hepatocellular carcinoma: an update
-
American Association for the Study of Liver Diseases.
-
Bruix J, Sherman M, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma: an update. HEPATOLOGY 2011; 53: 1020-1022.
-
(2011)
HEPATOLOGY
, vol.53
, pp. 1020-1022
-
-
Bruix, J.1
Sherman, M.2
-
19
-
-
84858658381
-
EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma
-
European Association for the Study of the Liver, European Organisation for Research and Treatment of Cancer.
-
European Association for the Study of the Liver, European Organisation for Research and Treatment of Cancer. EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol 2012; 56: 908-943.
-
(2012)
J Hepatol
, vol.56
, pp. 908-943
-
-
-
20
-
-
79955401037
-
Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma
-
Villanueva A, Hoshida Y, Battiston C, et al. Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma. Gastroenterology 2011; 140: 1501-1512.
-
(2011)
Gastroenterology
, vol.140
, pp. 1501-1512
-
-
Villanueva, A.1
Hoshida, Y.2
Battiston, C.3
-
21
-
-
34250195010
-
Decoding global gene expression programs in liver cancer by noninvasive imaging
-
Segal E, Sirlin CB, Ooi C, Adler AS, Gollub J, Chen X, et al. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nat Biotechnol 2007; 25: 675-680.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 675-680
-
-
Segal, E.1
Sirlin, C.B.2
Ooi, C.3
Adler, A.S.4
Gollub, J.5
Chen, X.6
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