Indole-3-carbinol blocks platelet-derived growth factor-stimulated vascular smooth muscle cell function and reduces neointima formation in vivo

Journal of Nutritional Biochemistry

Volumn 24, Issue 1, 2013, Pages 62-69

  Guan, Hongjing ^a,b   Chen, Changgui ^a,b   Zhu, Lihua ^a,b   Cui, Changping ^a,b   Guo, Yuanyuan ^a,b   Fu, Mingyue ^a,b   Wang, Lang ^a,b   Tang, Qizhu ^a,b  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

Indole 3 carbinol; Neointima; Platelet derived growth factor; Vascular smooth muscle cell

Indexed keywords

3 INDOLEMETHANOL; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLYCOGEN SYNTHASE KINASE 3BETA; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE B; CCND1 PROTEIN, RAT; INDOLE DERIVATIVE; INDOLE-3-CARBINOL; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR B; PLATELET-DERIVED GROWTH FACTOR BB;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CAROTID ARTERY INJURY; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; G1 PHASE CELL CYCLE CHECKPOINT; GROWTH INHIBITION; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MOUSE; MUSCLE CONTRACTILITY; NEOINTIMA; NONHUMAN; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ANIMAL; C57BL MOUSE; CELL MOTION; DRUG EFFECT; METABOLISM; PATHOLOGY; S PHASE CELL CYCLE CHECKPOINT; SPRAGUE DAWLEY RAT;

ANIMALS; CAROTID ARTERY INJURIES; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; G1 PHASE CELL CYCLE CHECKPOINTS; INDOLES; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, SMOOTH MUSCLE; NEOINTIMA; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-SIS; RATS; RATS, SPRAGUE-DAWLEY; S PHASE CELL CYCLE CHECKPOINTS;

EID: 84870475297     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2012.02.002     Document Type: Article

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