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Volumn 19, Issue 29, 2012, Pages 4969-4975

The effect of PAMAM dendrimers on mesenchymal stem cell viability and differentiation

Author keywords

Adipogenesis; Alkaline phosphatase activity; Cell viability; Cytotoxicity; Dendrimer; Differentiation; Human mesenchymal stem cells; Osteogenesis; PAMAM; Poly(amidoamine)

Indexed keywords

CARBOXYLIC ACID; DENDRIMER; HYDROXYL GROUP; POLYAMIDOAMINE;

EID: 84870470994     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867311209024969     Document Type: Article
Times cited : (13)

References (34)
  • 1
    • 77953434949 scopus 로고    scopus 로고
    • Emerging use of stem cells in regenerative medicine
    • Teo, A.K.K.; Vallier, L. Emerging use of stem cells in regenerative medicine. Biochem. J., 2010, 428, 11-23.
    • (2010) Biochem. J. , vol.428 , pp. 11-23
    • Teo, A.K.K.1    Vallier, L.2
  • 2
    • 53549108290 scopus 로고    scopus 로고
    • Regenerative medicine and stem cell based drug discovery
    • Sakurada, K.; McDonald, F.M.; Shimada, F. Regenerative medicine and stem cell based drug discovery. Angew. Chem. Int. Ed., 2008, 47, 5718-5738.
    • (2008) Angew. Chem. Int. Ed. , vol.47 , pp. 5718-5738
    • Sakurada, K.1    McDonald, F.M.2    Shimada, F.3
  • 5
    • 41549139755 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Revisiting history, concepts, and assays
    • Bianco, P.; Robey, P.G.; Simmons, P.J. Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell, 2008, 2, 313-319.
    • (2008) Cell Stem Cell , vol.2 , pp. 313-319
    • Bianco, P.1    Robey, P.G.2    Simmons, P.J.3
  • 7
    • 55749097943 scopus 로고    scopus 로고
    • Applications of nanomaterials inside cells
    • Gao, J.; Xu, B. Applications of nanomaterials inside cells. Nano Today, 2009, 4, 37-51.
    • (2009) Nano Today , vol.4 , pp. 37-51
    • Gao, J.1    Xu, B.2
  • 9
    • 56549109972 scopus 로고    scopus 로고
    • Nanotechnology for regenerative medicine: Nanomaterials for stem cell imaging
    • Solanki, A.; Kim, J.D.; Lee, K.-B. Nanotechnology for regenerative medicine: nanomaterials for stem cell imaging. Nanomedicine, 2008, 3, 567-578.
    • (2008) Nanomedicine , vol.3 , pp. 567-578
    • Solanki, A.1    Kim, J.D.2    Lee, K.-B.3
  • 10
    • 64549134676 scopus 로고    scopus 로고
    • Nonviral vectors for gene delivery
    • Mintzer, M.A.; Simanek, E.E. Nonviral vectors for gene delivery. Chem. Rev., 2009, 109, 259-302.
    • (2009) Chem. Rev. , vol.109 , pp. 259-302
    • Mintzer, M.A.1    Simanek, E.E.2
  • 11
    • 28744443398 scopus 로고    scopus 로고
    • Dendrimers in biomedical applications - Reflections on the field
    • Svenson, S.; Tomalia, D.A. Dendrimers in biomedical applications - reflections on the field. Adv. Drug Deliv. Rev., 2005, 57, 2106-2129.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 2106-2129
    • Svenson, S.1    Tomalia, D.A.2
  • 12
    • 77951234285 scopus 로고    scopus 로고
    • Dendrimers designed for functions: From physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, and nanomedicine
    • Astruc, D.; Boisselier, E.; Ornelas, C. Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, and nanomedicine. Chem. Rev., 2010, 110, 1857-1959.
    • (2010) Chem. Rev. , vol.110 , pp. 1857-1959
    • Astruc, D.1    Boisselier, E.2    Ornelas, C.3
  • 13
    • 60649096454 scopus 로고    scopus 로고
    • Osteogenic differentiation of mesenchymal stem cells using PAMAM dendrimers as gene delivery vectors
    • Santos, J.L.; Oramas, E.; Pêgo, A.P.; Granja, P.L.; Tomás, H. Osteogenic differentiation of mesenchymal stem cells using PAMAM dendrimers as gene delivery vectors. J. Control. Release, 2009, 134, 141-148.
    • (2009) J. Control. Release , vol.134 , pp. 141-148
    • Santos, J.L.1    Oramas, E.2    Pêgo, A.P.3    Granja, P.L.4    Tomás, H.5
  • 14
    • 79951658350 scopus 로고    scopus 로고
    • Delivery of the BMP-2 gene into MSCs: A biomimetic approach using RGD nanoclusters based on poly(amidoamine) dendrimers
    • Pandita, D.; Santos, J.L.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Tomás, H. Delivery of the BMP-2 gene into MSCs: a biomimetic approach using RGD nanoclusters based on poly(amidoamine) dendrimers. Biomacromolecules, 2011, 12, 472-481.
    • (2011) Biomacromolecules , vol.12 , pp. 472-481
    • Pandita, D.1    Santos, J.L.2    Rodrigues, J.3    Pêgo, A.P.4    Granja, P.L.5    Tomás, H.6
  • 17
    • 77953253240 scopus 로고    scopus 로고
    • Receptor-mediated gene delivery using PAMAM dendrimers conjugated with peptides recognized by mesenchymal stem cells
    • Santos, J.L.; Pandita, D.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Balian, G.; Tomás, H. Receptor-mediated gene delivery using PAMAM dendrimers conjugated with peptides recognized by mesenchymal stem cells. Mol. Pharmaceutics, 2010, 7, 763-774.
    • (2010) Mol. Pharmaceutics , vol.7 , pp. 763-774
    • Santos, J.L.1    Pandita, D.2    Rodrigues, J.3    Pêgo, A.P.4    Granja, P.L.5    Balian, G.6    Tomás, H.7
  • 18
    • 77953239685 scopus 로고    scopus 로고
    • Functionalization of Poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells
    • Santos, J.L.; Oliveira, H.; Pandita, D.; Rodrigues, J.; Pêgo, A.P.; Granja, P.L.; Tomás, H. Functionalization of Poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells. J. Control. Rel., 2010, 144, 55-64.
    • (2010) J. Control. Rel. , vol.144 , pp. 55-64
    • Santos, J.L.1    Oliveira, H.2    Pandita, D.3    Rodrigues, J.4    Pêgo, A.P.5    Granja, P.L.6    Tomás, H.7
  • 19
    • 79960556848 scopus 로고    scopus 로고
    • Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells
    • Higuchi, Y.; Wu, C.; Chang, K.-L.; Irie, K.; Kawakami, S.; Yamashita, F.; Hashida, M. Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells. Biomaterials, 2011, 32, 6676-6682.
    • (2011) Biomaterials , vol.32 , pp. 6676-6682
    • Higuchi, Y.1    Wu, C.2    Chang, K.-L.3    Irie, K.4    Kawakami, S.5    Yamashita, F.6    Hashida, M.7
  • 20
    • 57549117429 scopus 로고    scopus 로고
    • The osteogenic differentiation of rat bone marrow stromal cells cultured with dexamethasone-loaded carboxymethylchitosan/poly(amidoamine) dendrimer nanoparticles
    • Oliveira, J.M.; Sousa, R.A.; Kotobuki, N.; Tadokoro, M.; Hirose, M.; Mano, J.F.; Reis, R.L.; Ohgushi, H. The osteogenic differentiation of rat bone marrow stromal cells cultured with dexamethasone-loaded carboxymethylchitosan/ poly(amidoamine) dendrimer nanoparticles. Biomaterials, 2009, 30, 804-813.
    • (2009) Biomaterials , vol.30 , pp. 804-813
    • Oliveira, J.M.1    Sousa, R.A.2    Kotobuki, N.3    Tadokoro, M.4    Hirose, M.5    Mano, J.F.6    Reis, R.L.7    Ohgushi, H.8
  • 22
    • 79952149375 scopus 로고    scopus 로고
    • Intracellular release of 17-estradiol from cationic polyamidoamine dendrimer surface-modified poly (lactic-co-glycolic acid) microparticles improves osteogenic differentiation of human mesenchymal stromal cells
    • Hong, L.; Krishnamachari, Y.; Seabold, D.; Joshi, V.; Schneider, G.; Salem, A.K. Intracellular release of 17-estradiol from cationic polyamidoamine dendrimer surface-modified poly (lactic-co-glycolic acid) microparticles improves osteogenic differentiation of human mesenchymal stromal cells. Tissue Eng. Part C Methods, 2011, 17, 319-325.
    • (2011) Tissue Eng. Part C Methods , vol.17 , pp. 319-325
    • Hong, L.1    Krishnamachari, Y.2    Seabold, D.3    Joshi, V.4    Schneider, G.5    Salem, A.K.6
  • 23
    • 76149138854 scopus 로고    scopus 로고
    • PAMAM dendrimers - Diverse biomedical applications. Facts and unresolved questions
    • Labieniec, M.; Watala, C. PAMAM dendrimers - diverse biomedical applications. Facts and unresolved questions. Cent. Eur. J. Biol., 2009, 4, 434-451.
    • (2009) Cent. Eur. J. Biol. , vol.4 , pp. 434-451
    • Labieniec, M.1    Watala, C.2
  • 24
  • 25
    • 0034005436 scopus 로고    scopus 로고
    • Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo
    • Malik, N.; Wiwattanapatapee, R.; Klopsch, R.; Lorenz, K.; Frey, H.; Weener, J.W.; Meijer, E.W.; Paulus, W.; Duncan, R. Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J. Control. Release, 2000, 65, 133-48.
    • (2000) J. Control. Release , vol.65 , pp. 133-148
    • Malik, N.1    Wiwattanapatapee, R.2    Klopsch, R.3    Lorenz, K.4    Frey, H.5    Weener, J.W.6    Meijer, E.W.7    Paulus, W.8    Duncan, R.9
  • 26
    • 33751232325 scopus 로고    scopus 로고
    • Investigations on the toxicological profile of functionalized fifth-generation poly (propylene imine) dendrimer
    • Agashe, H.B.; Dutta, T.D.; Garg, M.; Jain, N.K. Investigations on the toxicological profile of functionalized fifth-generation poly (propylene imine) dendrimer. J. Pharm. Pharmacol., 2006, 58, 1491-1498.
    • (2006) J. Pharm. Pharmacol. , vol.58 , pp. 1491-1498
    • Agashe, H.B.1    Dutta, T.D.2    Garg, M.3    Jain, N.K.4
  • 28
    • 4043103282 scopus 로고    scopus 로고
    • Cytotoxicity, haemolysis, and acute in vivo toxicity of dendrimer based on melamine, candidate vehicles for drug delivery
    • Chen, H.T.; Neerman, M.F.; Parrish, A.R.; Simanek, E. Cytotoxicity, haemolysis, and acute in vivo toxicity of dendrimer based on melamine, candidate vehicles for drug delivery. J. Am. Chem. Soc., 2004, 126, 10044-10048.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 10044-10048
    • Chen, H.T.1    Neerman, M.F.2    Parrish, A.R.3    Simanek, E.4
  • 29
    • 0030042315 scopus 로고    scopus 로고
    • Preliminary biological evaluation of polyaminoamine (PAMAM) starburst dendrimers
    • Roberts, J.C.; Bhalgat, M.K.; Zera, R.T. Preliminary biological evaluation of polyaminoamine (PAMAM) starburst dendrimers. J. Biomed. Mater. Res., 1996, 30, 53-65.
    • (1996) J. Biomed. Mater. Res. , vol.30 , pp. 53-65
    • Roberts, J.C.1    Bhalgat, M.K.2    Zera, R.T.3
  • 30
    • 33644984490 scopus 로고    scopus 로고
    • A New Description of cellular quiescence
    • Coller, H.A.; Sang, L.; Roberts, J.M. A New Description of cellular quiescence. PLoS Biol., 2006, 4, e83.
    • (2006) PLoS Biol. , vol.4
    • Coller, H.A.1    Sang, L.2    Roberts, J.M.3
  • 32
    • 33646940975 scopus 로고    scopus 로고
    • Interaction of polycationic polymers with supported lipid bilayers and cells: Nanoscale hole formation and enhanced membrane permeability
    • Hong, S.; Leroueil, P.R.; Janus, E.K., Peters; J.L., Kober, M.M.; Islam, M.T.; Orr, B.G., Baker Jr.; J.R., Holl, M.M.B. Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability. Bioconjugate Chem., 2006, 17, 728-734.
    • (2006) Bioconjugate Chem. , vol.17 , pp. 728-734
    • Hong, S.1    Leroueil, P.R.2    Janus, E.K.3    Peters, J.L.4    Kober, M.M.5    Islam, M.T.6    Orr, B.G.7    Baker Jr., J.R.8    Holl, M.M.B.9
  • 34
    • 67349157229 scopus 로고    scopus 로고
    • Advances and Prospect of nanotechnology in stem cells
    • Wang, Z.; Ruan, J.; Cui, D. Advances and Prospect of nanotechnology in stem cells. Nanoscale Res. Lett., 2009, 4, 593-605.
    • (2009) Nanoscale Res. Lett. , vol.4 , pp. 593-605
    • Wang, Z.1    Ruan, J.2    Cui, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.