Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells

Biomaterials

Volumn 32, Issue 28, 2011, Pages 6676-6682

  Higuchi, Yuriko ^a,b   Wu, Can ^a   Chang, Kai Ling ^a   Irie, Kei ^a   Kawakami, Shigeru ^a   Yamashita, Fumiyoshi ^a   Hashida, Mitsuru ^a,c  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Buffering effect; Endosomal escape; In vivo imaging; PAMAM dendrimer; Quantum dot; Stem cell

Indexed keywords

ACIDIC CONDITIONS; BUFFERING CAPACITIES; BUFFERING EFFECT; CATIONIC CHARGES; CELLULAR UPTAKE; CULTURE PLATES; CYTOSOLIC; CYTOSOLS; ENDOSOMAL ESCAPE; ENDOSOMES; FLUORESCENCE EFFICIENCY; FLUORESCENCE INTENSITIES; IN VIVO IMAGING; IN-VIVO; MESENCHYMAL STEM CELL; PAMAM DENDRIMER; POLYAMIDOAMINE DENDRIMERS; POLYAMIDOAMINES; STEM CELL THERAPY;

CELL CULTURE; DENDRIMERS; FLOWCHARTING; FLUORESCENCE; MAMMALS; MOLECULAR BIOLOGY; SEMICONDUCTOR QUANTUM DOTS; STEM CELLS;

QUANTUM EFFICIENCY;

DENDRIMER; POLYAMIDOAMINE; QUANTUM DOT;

ACIDITY; ANIMAL EXPERIMENT; ARTICLE; BLEACHING; CELL CULTURE; CELL LABELING; CELL PH; CELL SURVIVAL; CONJUGATION; CONTROLLED STUDY; CYTOSOL; ENDOCYTOSIS; ENDOSOME; FLUORESCENCE; LYSOSOME; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATIC ELECTRICITY; STEM CELL TRANSPLANTATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELLS, CULTURED; DENDRIMERS; ENDOSOMES; FLUORESCENT DYES; MALE; MATERIALS TESTING; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; QUANTUM DOTS;

MUS;

EID: 79960556848     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.05.076     Document Type: Article

References (38)

1. Hodgkinson C.P., Gomez J.A., Mirotsou M., Dzau V.J. Genetic engineering of mesenchymal stem cells and its application in human disease therapy. Hum Gene Ther 2010, 21:1513-1526.
2. Chen F.M., Wu L.A., Zhang M., Zhang R., Sun H.H. Homing of endogenous stem/progenitor cells for in situ tissue regeneration: promises, strategies, and translational perspectives. Biomaterials 2011, 32:3189-3209.
3. Mazzini L., Ferrero I., Luparello V., Rustichelli D., Gunetti M., Mareschi K., et al. Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: a phase I clinical trial. Exp Neurol 2010, 223:229-237.
4. Hare J.M., Traverse J.H., Henry T.D., Dib N., Strumpf R.K., Schulman S.P., et al. A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (Prochymal) after acute myocardial infarction. J Am Coll Cardiol 2009, 54:2277-2286.
5. Kharaziha P., Hellstrom P.M., Noorinayer B., Farzaneh F., Aghajani K., Jafari F., et al. Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I-II clinical trial. Eur Gastroenterol Hepatol 2009, 21:1199-1205.
6. Venkataramana N.K., Kumar S.K.V., Balaraju S., Radhakrishnan R.C., Bansal A., Dixit A., et al. Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal stem cell transplantation in Parkinson's disease. Transl Res 2010, 155:62-70.
7. Terrovitis J.V., Smith R.R., Marban E. Assessment and optimization of cell engraftment after transplantation into the heart. Circ Res 2010, 106:479-494.
8. Srinivas M., Aarntzen E., Bulte J.W.M., Oyen W.J., Heerschap A., de Vries I.J.M., et al. Imaging of cellular therapies. Adv Drug Deliv Rev 2010, 62:1080-1093.
9. Nohroudi K., Arnhold S., Berhorn T., Addicks K., Hoehn M., Himmelreich U. In vivo MRI stem cell tracking requires balancing of detection limit and cell viability. Cell Transplant 2010, 19:431-441.
10. Sykova E., Jendelova P. Migration, fate and in vivo imaging of adult stem cells in the CNS. Cell Death Differ 2007, 14:1336-1342.
11. Aicher A., Brenner W., Zuhayra M., Badorff C., Massoudi S., Assmus B., et al. Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling. Circulation 2003, 107:2134-2139.
12. Barbash I.M., Chouraqui P., Baron J., Feinberg M.S., Etzion S., Tessone A., et al. Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium - feasibility, cell migration, and body distribution. Circulation 2003, 108:863-868.
13. Nishimura S., Manabe I., Nagasaki M., Seo K., Yamashita H., Hosoya Y., et al. In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. J Clin Invest 2008, 118:710-721.
14. Michalet X., Pinaud F.F., Bentolila L.A., Tsay J.M., Doose S., Li J.J., et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 2005, 307:538-544.
15. Medintz I.L., Uyeda H.T., Goldman E.R., Mattoussi H. Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mater 2005, 4:435-446.
16. Gao X.H., Cui Y.Y., Levenson R.M., Chung L.W.K., Nie S.M. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 2004, 22:969-976.
17. Lin S., Xie X.Y., Patel M.R., Yang Y.H., Li Z.J., Cao F., et al. Quantum dot imaging for embryonic stem cells. BMC Biotechnol 2007, 7.
18. Wang H., Cao F., De A., Cao Y., Contag C., Gambhir S.S., et al. Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. Stem Cells 2009, 27:1548-1558.
19. Liu Y.S., Sun Y.H., Vernier P.T., Liang C.H., Chong S.Y.C., Gundersen M.A. pH-sensitive photoluminescence of CdSe/ZnSe/ZnS quantum dots in human ovarian cancer cells. J Phys Chem C 2007, 111:2872-2878.
20. Mandal A., Tamai N. Influence of acid on luminescence properties of thioglycolic acid-capped CdTe quantum dots. J Phys Chem C 2008, 112:8244-8250.
21. Silver J., Ou W. Photoactivation of quantum dot fluorescence following endocytosis. Nano Lett 2005, 5:1445-1449.
22. Higuchi Y., Kawakami S., Hashida M. Strategies for in vivo delivery of siRNAs recent progress. Bio Drugs 2010, 24:195-205.
23. Kawakami S., Higuchi Y., Hashida M. Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide. J Pharm Sci 2008, 97:726-745.
24. Akinc A., Thomas M., Klibanov A.M., Langer R. Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J Gene Med 2005, 7:657-663.
25. Sonawane N.D., Szoka F.C., Verkman A.S. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem 2003, 278:44826-44831.
26. van Duijvenbode R.C., Borkovec M., Koper G.J.M. Acid-base properties of poly(propylene imine) dendrimers. Polymer 1998, 39:2657-2664.
27. Duan H.W., Nie S.M. Cell-penetrating quantum dots based on multivalent and endosome-disrupting surface coatings. J Am Chem Soc 2007, 129:3333-3338.
28. 4-injured rats. J Hepatol 2006, 44:742-748.
29. Ohyabu Y., Kaul Z., Yoshioka T., Inoue K., Sakai S., Mishima H., et al. Stable and nondisruptive in vitro/in vivo labeling of mesenchymal stem cells by internalizing quantum dots. Hum Gene Ther 2009, 20:217-224.
30. Higuchi Y., Oka M., Kawakami S., Hashida M. Mannosylated semiconductor quantum dots for the labeling of macrophages. J Control Release 2008, 125:131-136.
31. Hanaki K., Momo A., Oku T., Komoto A., Maenosono S., Yamaguchi Y., et al. Semiconductor quantum dot/albumin complex is a long-life and highly photostable endosome marker. Biochem Biophys Res Commun 2003, 302:496-501.
32. Hoshino A., Hanaki K., Suzuki K., Yamamoto K. Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse body. Biochem Biophys Res Commun 2004, 314:46-53.
33. Kichler A., Leborgne C., Coeytaux E., Danos O. Polyethylenimine-mediated gene delivery: a mechanistic study. J Gene Med 2001, 3:135-144.
34. Kircheis R., Wightman L., Schreiber A., Robitza B., Rossler V., Kursa M., et al. Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther 2001, 8:28-40.
35. Saito Y., Higuchi Y., Kawakami S., Yamashita F., Hashida M. Immunostimulatory characteristics induced by linear polyethyleneimine-plasmid DNA complexes in cultured macrophages. Hum Gene Ther 2009, 20:137-145.
36. Kraitchman D.L., Tatsumi M., Gilson W.D., Ishimori T., Kedziorek D., Walczak P., et al. Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation 2005, 112:1451-1461.
37. Varkouhi A.K., Scholte M., Storm G., Haisma H.J. Endosomal escape pathways for delivery of biologicals. J Control Release 2011, 151:220-228.
38. Okuda T., Sugiyama A., Niidome T., Aoyagi H. Characters of dendritic poly((L)-lysine) analogues with the terminal lysines replaced with arginines and histidines as gene carriers in vitro. Biomaterials 2004, 25:537-544.