-
1
-
-
65949092291
-
PIK3CA mutations in human solid tumors: Role in sensitivity to various therapeutic approaches
-
http://dx.doi.org/10.4161/cc.8.9.8255
-
Ligresti G, Militello L, Steelman LS, Cavallaro A, Basile F, Nicoletti F, et al. PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches. Cell Cycle. 2009;8(9):1352-1358, http://dx.doi.org/10.4161/cc.8.9.8255.
-
(2009)
Cell Cycle
, vol.8
, Issue.9
, pp. 1352-1358
-
-
Ligresti, G.1
Militello, L.2
Steelman, L.S.3
Cavallaro, A.4
Basile, F.5
Nicoletti, F.6
-
2
-
-
79959334964
-
Present and future of PI3K pathway inhibition in cancer: Perspectives and limitations
-
http://dx.doi.org/10.2174/092986711796011193
-
Ciraolo E, Morello F, Hirsch E. Present and future of PI3K pathway inhibition in cancer: perspectives and limitations. Curr Med Chem. 2011;18(18):2674-2685, http://dx.doi.org/10.2174/092986711796011193.
-
(2011)
Curr Med Chem
, vol.18
, Issue.18
, pp. 2674-2685
-
-
Ciraolo, E.1
Morello, F.2
Hirsch, E.3
-
3
-
-
79952108510
-
Oncogenic mutations of PIK3CA in human cancers
-
http://dx.doi.org/10.1007/82_2010_68
-
Samuels Y, Waldman T. Oncogenic mutations of PIK3CA in human cancers. Curr Top Microbiol Immunol. 2010;347:21-41, http://dx.doi.org/10.1007/82_2010_68.
-
(2010)
Curr Top Microbiol Immunol
, vol.347
, pp. 21-41
-
-
Samuels, Y.1
Waldman, T.2
-
4
-
-
38749116169
-
Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas
-
Murugan AK, Hong NT, Fukui Y, Munirajan AK, Tsuchida N. Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas. Int J Oncol. 2008;32(1):101-111.
-
(2008)
Int J Oncol
, vol.32
, Issue.1
, pp. 101-111
-
-
Murugan, A.K.1
Hong, N.T.2
Fukui, Y.3
Munirajan, A.K.4
Tsuchida, N.5
-
5
-
-
33646706052
-
Oncogenic PI3K and its role in cancer
-
http://dx.doi.org/10.1097/01.cco.0000198021.99347.b9
-
Samuels Y, Ericson K. Oncogenic PI3K and its role in cancer. Curr Opin Oncol. 2006;18(1):77-82, http://dx.doi.org/10.1097/01.cco.0000198021.99347.b9.
-
(2006)
Curr Opin Oncol
, vol.18
, Issue.1
, pp. 77-82
-
-
Samuels, Y.1
Ericson, K.2
-
6
-
-
66149141021
-
PTEN and the PI3-kinase pathway in cancer
-
Chalhoub N, Baker SJ. PTEN and the PI3-kinase pathway in cancer. Annu Rev Pathol. 2009;4:127-150.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 127-150
-
-
Chalhoub, N.1
Baker, S.J.2
-
7
-
-
79952198405
-
The phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancer
-
http://dx.doi.org/10.1007/s10555-010-9261-0
-
Castaneda CA, Cortes-Funes H, Gomez HL, Ciruelos EM. The phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancer. Cancer Metastasis Rev. 2010;29(4):751-759, http://dx.doi.org/10.1007/s10555-010-9261-0.
-
(2010)
Cancer Metastasis Rev
, vol.29
, Issue.4
, pp. 751-759
-
-
Castaneda, C.A.1
Cortes-Funes, H.2
Gomez, H.L.3
Ciruelos, E.M.4
-
8
-
-
48949119513
-
PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer
-
http://dx.doi.org/10.1186/bcr1984
-
Liedtke C, Cardone L, Tordai A, Yan K, Gomez HL, Figureoa LJ, et al. PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer. Breast Cancer Res. 2008;10(2):R27, http://dx.doi.org/10.1186/bcr1984.
-
(2008)
Breast Cancer Res
, vol.10
, Issue.2
-
-
Liedtke, C.1
Cardone, L.2
Tordai, A.3
Yan, K.4
Gomez, H.L.5
Figureoa, L.J.6
-
9
-
-
79951834210
-
PIK3CA mutations may be discordant between primary and corresponding metastatic disease in breast cancer
-
http://dx.doi.org/10.1158/1078-0432.CCR-10-1133
-
Dupont Jensen J, Laenkholm AV, Knoop A, Ewertz M, Bandaru R, Liu W, et al. PIK3CA mutations may be discordant between primary and corresponding metastatic disease in breast cancer. Clin Cancer Res. 2011;17(4):667-677, http://dx.doi.org/10.1158/1078-0432.CCR-10-1133.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.4
, pp. 667-677
-
-
Dupont, J.J.1
Laenkholm, A.V.2
Knoop, A.3
Ewertz, M.4
Bandaru, R.5
Liu, W.6
-
10
-
-
56249147845
-
PIK3CA gene mutations in breast carcinoma in Malaysian patients
-
http://dx.doi.org/10.1016/j.cancergencyto.2008.07.005
-
V Ching-Shian, Leong V, Jabal MF, Leong PP, Abdullah MA, Gul YA, Seow HF. PIK3CA gene mutations in breast carcinoma in Malaysian patients. Cancer Genet Cytogenet. 2008;187(2):74-79, http://dx.doi.org/10.1016/j.cancergencyto.2008.07.005.
-
(2008)
Cancer Genet Cytogenet
, vol.187
, Issue.2
, pp. 74-79
-
-
Ching-Shian, V.1
Leong, V.2
Jabal, M.F.3
Leong, P.P.4
Abdullah, M.A.5
Gul, Y.A.6
Seow, H.F.7
-
11
-
-
33846854921
-
Clinicopathologic analysis of breast cancers with PIK3CA mutations in Japanese women
-
http://dx.doi.org/10.1158/1078-0432.CCR-06-0267
-
Maruyama N, Miyoshi Y, Taguchi T, Tamaki Y, Monden M, Noguchi S. Clinicopathologic analysis of breast cancers with PIK3CA mutations in Japanese women. Clin Cancer Res. 2007;13(2PT 1):408-414, http://dx.doi.org/10.1158/1078-0432.CCR-06-0267.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.2 PT 1
, pp. 408-414
-
-
Maruyama, N.1
Miyoshi, Y.2
Taguchi, T.3
Tamaki, Y.4
Monden, M.5
Noguchi, S.6
-
12
-
-
51049118140
-
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
-
http://dx.doi.org/10.1158/0008-5472.CAN-07-6854
-
Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, Neve RM, Kuo WL, Davies M, et al. An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. Cancer Res. 2008; 68(15):6084-6091, http://dx.doi.org/10.1158/0008-5472.CAN-07-6854.
-
(2008)
Cancer Res
, vol.68
, Issue.15
, pp. 6084-6091
-
-
Stemke-Hale, K.1
Gonzalez-Angulo, A.M.2
Lluch, A.3
Neve, R.M.4
Kuo, W.L.5
Davies, M.6
-
13
-
-
69349105634
-
PIK3CA mutation associates with improved outcome in breast cancer
-
http://dx.doi.org/10.1158/1078-0432.CCR-09-0632
-
Kalinsky K, Jacks LM, Heguy A, Patil S, Drobnjak M, Bhanot UK, et al. PIK3CA mutation associates with improved outcome in breast cancer. Clin Cancer Res. 2009;15(16):5049-5059, http://dx.doi.org/10.1158/1078-0432.CCR-09-0632.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.16
, pp. 5049-5059
-
-
Kalinsky, K.1
Jacks, L.M.2
Heguy, A.3
Patil, S.4
Drobnjak, M.5
Bhanot, U.K.6
-
14
-
-
33645224005
-
PIK3CA mutations in breast cancer are associated with poor outcome
-
http://dx.doi.org/10.1007/s10549-005-9048-0
-
Li SY, Rong M, Grieu F, Iacopetta B. PIK3CA mutations in breast cancer are associated with poor outcome. Breast Cancer Res Treat. 2006;96(1):91-95, http://dx.doi.org/10.1007/s10549-005-9048-0.
-
(2006)
Breast Cancer Res Treat
, vol.96
, Issue.1
, pp. 91-95
-
-
Li, S.Y.1
Rong, M.2
Grieu, F.3
Iacopetta, B.4
-
15
-
-
35948964043
-
Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas
-
http://dx.doi.org/10.1158/1078-0432.CCR-07-0266
-
Barbareschi M, Buttitta F, Felicioni L, Cotrupi S, Barassi F, Del Grammastro M, et al. Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas. Clin Cancer Res. 2007;13(20):6064-6069, http://dx.doi.org/10.1158/1078-0432.CCR-07-0266.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.20
, pp. 6064-6069
-
-
Barbareschi, M.1
Buttitta, F.2
Felicioni, L.3
Cotrupi, S.4
Barassi, F.5
Del Grammastro, M.6
-
16
-
-
40549113364
-
PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients
-
http://dx.doi.org/10.1245/s10434-007-9751-7
-
Lai YL, Mau BL, Cheng WH, Chen HM, Chiu HH, Tzen CY. PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients. Ann Surg Oncol. 2008;15(4):1064-1069, http://dx.doi.org/10.1245/s10434-007-9751-7.
-
(2008)
Ann Surg Oncol
, vol.15
, Issue.4
, pp. 1064-1069
-
-
Lai, Y.L.1
Mau, B.L.2
Cheng, W.H.3
Chen, H.M.4
Chiu, H.H.5
Tzen, C.Y.6
-
17
-
-
1542540821
-
TP53 mutations in primary breast carcinomas from white and African-Brazilian patients
-
Nagai MA, Schaer Barbosa H, Zago MA, Araújo Silva W Jr, Nishimoto IN, Salaorni S, et al. TP53 mutations in primary breast carcinomas from white and African-Brazilian patients. Int J Oncol. 2003;23(1):189-196.
-
(2003)
Int J Oncol
, vol.23
, Issue.1
, pp. 189-196
-
-
Nagai, M.A.1
Schaer, B.H.2
Zago, M.A.3
Araújo, S.W.4
Nishimoto, I.N.5
Salaorni, S.6
-
18
-
-
20144387695
-
PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma
-
http://dx.doi.org/10.1158/0008-5472-CAN-04-3913
-
Saal LH, Holm K, Maurer M, Memeo L, Su T, Wang X, et al. PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. Cancer Res. 2005;65(7):2554-2559, http://dx.doi.org/10.1158/0008-5472-CAN-04-3913.
-
(2005)
Cancer Res
, vol.65
, Issue.7
, pp. 2554-2559
-
-
Saal, L.H.1
Holm, K.2
Maurer, M.3
Memeo, L.4
Su, T.5
Wang, X.6
-
19
-
-
84857921336
-
Mutational characterization of individual breast tumors: TP53 and PI3K pathway genes are frequently and distinctively mutated in different subtypes
-
http://dx.doi.org/10.1007/s10549-011-1518-y
-
Boyault S, Drouet Y, Navarro C, Bachelot T, Lasset C, Treilleux I, et al. Mutational characterization of individual breast tumors: TP53 and PI3K pathway genes are frequently and distinctively mutated in different subtypes. Breast Cancer Res Treat. 2012;132(1):29-39, http://dx.doi.org/10.1007/s10549-011-1518-y.
-
(2012)
Breast Cancer Res Treat
, vol.132
, Issue.1
, pp. 29-39
-
-
Boyault, S.1
Drouet, Y.2
Navarro, C.3
Bachelot, T.4
Lasset, C.5
Treilleux, I.6
-
20
-
-
74549137913
-
PIK3CA in breast carcinoma: A mutational analysis of sporadic and hereditary cases
-
http://dx.doi.org/10.1097/PDM.0b013e31818e5fa4
-
Michelucci A, Di Cristofano C, Lami A, Collecchi P, Caligo A, Decarli N, et al. PIK3CA in breast carcinoma: a mutational analysis of sporadic and hereditary cases. Diagn Mol Pathol. 2009;18(4):200-205, http://dx.doi.org/10.1097/PDM.0b013e31818e5fa4.
-
(2009)
Diagn Mol Pathol
, vol.18
, Issue.4
, pp. 200-205
-
-
Michelucci, A.1
Di Cristofano, C.2
Lami, A.3
Collecchi, P.4
Caligo, A.5
Decarli, N.6
-
21
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
http://dx.doi.org/10.1126/science.1145720
-
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, et al. The genomic landscapes of human breast and colorectal cancers. Science. 2007;318(5853):1108-1113, http://dx.doi.org/10.1126/science.1145720.
-
(2007)
Science
, vol.318
, Issue.5853
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjöblom, T.5
Leary, R.J.6
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