Heat shock protein 70 (Hsp70) inhibits oxidative phosphorylation and compensates ATP balance through enhanced glycolytic activity

Journal of Applied Physiology

Volumn 113, Issue 11, 2012, Pages 1669-1676

  Wang, Liangli ^a   Schumann, Uwe ^a   Liu, Yuefei ^a   Prokopchuk, Olga ^a   Steinacker, Jürgen M ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Adaptation to heat stress; Glycolysis; HeLa cells; ROS

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ADENOSINE TRIPHOSPHATE; CITRATE SYNTHASE; GLUCOSE; HEAT SHOCK PROTEIN 70; LACTATE DEHYDROGENASE; LACTIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ADAPTATION; ARTICLE; CITRIC ACID CYCLE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; GLYCOLYSIS; HELA CELL; HUMAN; METABOLISM; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION;

ADAPTATION, PHYSIOLOGICAL; ADENOSINE TRIPHOSPHATE; CITRATE (SI)-SYNTHASE; CITRIC ACID CYCLE; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX III; GENE EXPRESSION REGULATION; GLUCOSE; GLYCOLYSIS; HELA CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; L-LACTATE DEHYDROGENASE; LACTIC ACID; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; PHOSPHOFRUCTOKINASES; TRANSFECTION;

EID: 84870441086     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00658.2012     Document Type: Article

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