Ventricular repolarization in diabetic patients: Characterization and clinical implications

Arquivos Brasileiros de Cardiologia

Volumn 99, Issue 5, 2012, Pages 1015-1022

  Clemente, David ^a   Pereira, Telmo ^b,d   Ribeiro, Susana ^c  

^a Unidade de Cuidados de Saúde Personalizados de Salvaterra de Magos   (Portugal)

^b Escola Superior de Tecnologia da Saúde de Coimbra   (Portugal)

^c Unidade de Saúde Familiar de Samora Correia   (Portugal)

^d Universidade Metodista de Angola   (Angola)

Author keywords

Arrhythmias cardiac; Cardiac; Death; Diabetes mellitus; Electrocardiography; Sudden

Indexed keywords

HEMOGLOBIN A1C;

ADULT; BELOW KNEE AMPUTATION; BLINDNESS; BODY MASS; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETIC PATIENT; DIASTOLIC BLOOD PRESSURE; DYSLIPIDEMIA; ELECTROCARDIOGRAPHY; ELECTROCARDIOGRAPHY MONITORING; FEMALE; HEART FAILURE; HEART INFARCTION; HEART REPOLARIZATION; HEART VENTRICLE ARRHYTHMIA; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; KIDNEY DISEASE; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; NEUROPATHY; QRS COMPLEX; QT DISPERSION; QT INTERVAL; QT PROLONGATION; QTC INTERVAL; RETINOPATHY; REVIEW; SYSTOLIC BLOOD PRESSURE; T WAVE;

AGED; ARRHYTHMIAS, CARDIAC; CONTROL GROUPS; DIABETES MELLITUS; ELECTROCARDIOGRAPHY; EPIDEMIOLOGIC METHODS; FEMALE; HEART RATE; HEART VENTRICLES; HUMANS; MALE; MIDDLE AGED; REFERENCE VALUES; TIME FACTORS;

EID: 84870431665     PISSN: 0066782X     EISSN: 16784170     Source Type: Journal    
DOI: 10.1590/S0066-782X2012005000095     Document Type: Review

References (39)

1. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87(1):4-14.
2. Kumar R, Fisher M, Macfarlane PW. Diabetes and QT interval: time for debate. Br J Diabetes Vasc Dis.2004;4:146-9.
3. Okin PM, Devereux RB, Howard BV, Fabsitz RR, Lee ET, Welty TK. Assessment of QT interval and QT dispersion for prediction of all-cause and cardiovascular mortality in American Indians: The Strong Heart Study. Circulation. 2000;101(1):61-6.
4. Cardoso CR, Salles GF, Deccache W. Prognostic value of QT interval parameters in type 2 diabetes mellitus: results of a long-term follow-up prospective study. J Diabetes Complications. 2003;17(4):169-78.
5. Veglio M, Chinaglia A, Cavallo-Perin P. QT interval, cardiovascular risk factors and risk of death in diabetes. J Endocrinol Invest. 2004;27(2):175-81.
6. Sá R, Perez C. Dispersão de QT: o seu significado clínico. Rev SOCERJ. 2004;17(3):183-91.
7. Haverkamp W, Breithardt G, Camm AJ, Janse MJ, Rosen MR, Antzelevitch C, et al. The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology. Eur Heart J. 2000;21(15):1216-31.
8. Corrado D, Pelliccia A, Bjornstad HH, Vanhees L, Biffi A, Borjesson M, et al. Cardiovascular pre-participation screening of young competitive athletes for prevention of sudden death: proposal for a common European protocol. Consensus Statement of the Study Group of Sport Cardiology of the Working Group of Cardiac Rehabilitation and Exercise Physiology and the Working Group of Myocardial and Pericardial Diseases of the European Society of Cardiology. Eur Heart J. 2005;26(5):516-24.
9. Surawicz B. Will QT dispersion play a role in clinical decision-making? J Cardiovasc Electrophysiol. 1996;7(8):777-84.
10. Salles GF, Deccache W, Cardoso CR. Usefulness of QT-interval parameters for cardiovascular risk stratification in type 2 diabetic patients with arterial hypertension. J Hum Hypertens. 2005;19(3):241-9.
11. Castro Hevia J, Antzelevitch C, Tornes Barzaga F, Dorantes Sanchez M, Dorticos Balea F, Zayas Molina R, et al. Tpeak-Tend and Tpeak-Tend dispersion as risk factors for ventricular tachycardia/ventricular fibrillation in patients with the Brugada syndrome. J Am Coll Cardiol. 2006;47(9):1828-34.
12. Mozos I, Serban C. The relation between QT interval and T-wave variables in hypertensive patients. J Pharm Bioallied Sci. 2011;3(3):339-44.
13. James PT, Leach R, Kalamara E, Shayeghi M. The worldwide obesity epidemic. Obes Res. 2001;9 (Suppl 4):228S-33S.
14. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, et al. 2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension. J Hypertens. 2007;25(9):1751-62.
15. Kratz A, Ferraro M, Sluss PM, Lewandrowski KB. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Laboratory reference values. N Engl J Med. 2004;351(15):1548-63.
16. Yoon JS, Won KC, Lee HW. The relation of QTc dispersion and cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus. J Korean Diabetes Assoc. 1998;22(3):410-18.
17. Kumhar MR, Agarwal TD, Singh VB, Kochar DK, Chadda VS. Cardiac autonomic neuropathy and its correlation with QTc dispersion in type 2 diabetes. Indian Heart J. 2000;52(4):421-6.
18. Familoni OB, Odusan O, Raimi TH. The relationship between QT intervals and cardiac autonomic neuropathy in nigerian patients with type 2 diabetes mellitus. Niger Med Pract. 2008;53(3):48-51.
19. Arildsen H, May O, Christiansen EH, Damsgaard EM. Increased QT dispersion in patients with insulin-dependent diabetes mellitus. Int J Cardiol. 1999;71(3):235-42.
20. Langen KJ, Ziegler D, Weise F, Piolot R, Boy C, Hubinger A, et al. Evaluation of QT interval length, QT dispersion and myocardial m-iodobenzylguanidine uptake in insulin-dependent diabetic patients with and without autonomic neuropathy. Clin Sci (Lond). 1997;93(4):325-33.
21. Takebayashi K, Aso Y, Sugita R, Takemura Y, Inukai T. Clinical usefulness of corrected QT intervals in diabetic autonomic neuropathy in patients with type 2 diabetes. Diabetes Metab. 2002;28(2):127-32.
22. Jermendy G, Koltai MZ, Pogatsa G. QT interval prolongation in type 2 (non-insulin-dependent) diabetic patients with cardiac autonomic neuropathy. Acta Diabetol Lat. 1990;27(4):295-301.
23. Sakabe K, Fukuda N, Fukuda Y, Wakayama K, Nada T, Morishita S, et al. QT-interval dispersion in type 2 diabetic and non-diabetic patients with post-myocardial infarction. Nutr Metab Cardiovasc Dis. 2008;18(2):121-6.
24. Takebayashi K, Sugita R, Tayama K, Aso Y, Takemura Y, Inukai T. The connection between QT dispersion and autonomic neuropathy in patients with type 2 diabetes. Exp Clin Endocrinol Diabetes. 2003;111(6):351-7.
25. Aytemir K, Aksoyek S, Ozer N, Gurlek A, Oto A. QT dispersion and autonomic nervous system function in patients with type 1 diabetes. Int J Cardiol. 1998;65(1):45-50.
26. Galetta F, Franzoni F, Prattichizzo F, Tintori G, Cinotti F, Taccola D, et al. [QT dispersion in insulin-dependent diabetics]. G Ital Cardiol. 1999 Jun;29(6):675-8.
27. Cardoso C, Salles G, Bloch K, Deccache W, Siqueira-Filho AG. Clinical determinants of increased QT dispersion in patients with diabetes mellitus. Int J Cardiol. 2001;79(2-3):253-62.
28. Deyneli O, Ersoz HO, Yavuz D, Fak AS, Akalin S. QT dispersion in type 2 diabetic patients with altered diurnal blood pressure rhythm. Diabetes Obes Metab. 2005;7(2):136-43.
29. Lengyel C, Varkonyi T, Boda K, Fazekas T. [Increase of the QT interval dispersion in diabetes mellitus]. Orv Hetil. 1997;138(6):337-41.
30. Wei K, Dorian P, Newman D, Langer A. Association between QT dispersion and autonomic dysfunction in patients with diabetes mellitus. J Am Coll Cardiol. 1995;26(4):859-63.
31. Psallas M, Tentolouris N, Papadogiannis D, Doulgerakis D, Kokkinos A, Cokkinos DV, et al. QT dispersion: comparison between participants with Type 1 and 2 diabetes and association with microalbuminuria in diabetes. J Diabetes Complications. 2006;20(2):88-97.
32. Gupta P, Patel C, Patel H, Narayanaswamy S, Malhotra B, Green JT, et al. T(p-e)/QT ratio as an index of arrhythmogenesis. J Electrocardiol. 2008;41(6):567-74.
33. Costa EC, Goncalves AA, Areas MA, Morgabel RG. Effects of metformin on QT and QTc interval dispersion of diabetic rats. Arq Bras Cardiol. 2008;90(4):232-8.
34. Vilas-Boas F, Castro Lima A, Torreão J, Feitosa GS. Dispersão Temporal do QT em Pacientes com Hipertensão Arterial Sistêmica. Arq Bras Cardiol. 1997;68(5):343-6.
35. Faramawi MF, Wildman RP, Gustat J, Rice J, Abdul Kareem MY. The association of the metabolic syndrome with QTc interval in NHANES III. Eur J Epidemiol. 2008;23(7):459-65.
36. Robinson RT, Harris ND, Ireland RH, Lee S, Newman C, Heller SR. Mechanisms of abnormal cardiac repolarization during insulin-induced hypoglycemia. Diabetes. 2003;52(6):1469-74.
37. Veglio M, Giunti S, Stevens LK, Fuller JH, Perin PC. Prevalence of Q-T interval dispersion in type 1 diabetes and its relation with cardiac ischemia: the EURODIAB IDDM Complications Study Group. Diabetes Care. 2002;25(4):702-7.
38. Sawicki PT. Mortality in diabetic nephropathy: the importance of the QT interval. Nephrol Dial Transplant. 1996;11(8):1514-5.
39. Szlejf C, Rays J, Gebara OC, Vieira NW, Pierri H, Nussbacher A, et al. Relação entre os Comportamentos das Dispersões da Onda P e do Intervalo QT em Idosos com Insuficiência Cardíaca. Arq Bras Cardiol. 2002;79:494-6.