The death of specificity in Psychiatry

Perspectives in Biology and Medicine

Volumn 55, Issue 3, 2012, Pages 443-460

  Dean, Charles E ^a  

^a Staff Psychiatrist and Director   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PSYCHOTROPIC AGENT;

ARTICLE; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; HISTORY; HUMAN; MASS COMMUNICATION; MENTAL DISEASE; OFF LABEL DRUG USE; PREDICTIVE VALUE; PSYCHIATRY; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL RATING SCALE; SENSITIVITY AND SPECIFICITY;

DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIFFUSION OF INNOVATION; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; MENTAL DISORDERS; OFF-LABEL USE; PREDICTIVE VALUE OF TESTS; PSYCHIATRIC STATUS RATING SCALES; PSYCHIATRY; PSYCHOTROPIC DRUGS; SENSITIVITY AND SPECIFICITY;

EID: 84870418339     PISSN: 00315982     EISSN: None     Source Type: Journal    
DOI: 10.1353/pbm.2012.0028     Document Type: Article

References (73)

1. Alessi-Severini, S., et al. 2012. Ten years of antipsychotic prescribing to children:A Canadian population-based study. Can J Psychiatry 57:52-8.
2. Alexander, G. C., et al. 2011. Increasing off-label use of antipsychotic medications in theUnited States, 1995-2008. Pharmacoepidemiol Drug Saf 20:177-84.
3. American Diabetes Association, American Psychiatric Association, American Association of Clinical Endocrinologists, North American Association for the Study of Obesity. 2004. Consensus development conference on antipsychotic drugs and obesity and diabetes. Diabetes Care 27:596-601.
4. American Psychiatric Association (APA). 1980 Diagnostic and statistical manual of mental disorders. 3rd ed. (DSM-III). Washington, DC: APA. DSM-I and DSM-II were published in 1952 and 1968, respectively. The latest edition, DSM-IV, Text Revision, was published in 2000. DSM-5 is scheduled for publication in 2013.
5. Andreasen, N. S. 1984. The broken brain. NewYork: Harper & Row.
6. Andreasen, N. S. 2007. DSM and the death of phenomenology in America:An example of unintended consequences. Schizophr Bull 33:108-12.
7. Baldessarini, R. J. 2000. American biological psychiatry and psychopharmacology, 1944-1994. In American psychiatry afterWorldWar II (1944-1994), ed. R.W. Menninger and J. C. Nemiah 371-412. Washington, DC:American Psychiatric Press.
8. Braslow, J. 1997. Mental ills and bodily cures. Berkeley: Univ. of California Press.
9. Breier, A. 2011. Anxiety disorders and antipsychotic drugs:A pressing need for more research. Am J Psychiatry 168:1012-14.
10. Comer, J. S., R. Mojtabai, and M. Olfson. 2011. National trends in the antipsychotic treatment of psychiatric outpatients with anxiety disorders. Am J Psychiatry 168:1057-65.
11. Crabbe, J. C., D. Wahlsten, and B. C. Dudek. 1999. Genetics of mouse behavior: Interactions with laboratory environment. Science 284:1670-72.
12. Craddock, N., and M. J. Owen. 2005. The beginning of the end for the Kraeplinian dichotomy. Br J Psychiatry 186:364-66.
13. Crystal S., et al. 2009. Broadened use of atypical antipsychotics: safety, effectiveness, and policy challenges. Health Aff (Millwood) 28:w770-81.
14. Dean, C. E. 1991. Diagnosis:The Achilles' heel of biological psychiatry. Minn Med 74: 15-17.
15. Dean, C. E. 2011. Psychopharmacology:A house divided. Prog Neuropsychopharmacol Biol Psychiatry 35:1-10.
16. Dean, K., et al. 2010. Full spectrum of psychiatric outcomes among offspring with parental history of mental disorders. Arch Gen Psychiatry 67:822-29.
17. Erlenmeyer-Kimling, L., et al. 1997. The NewYork High-Risk Project: Prevalence and comorbidity of axis I disorders in offspring of schizophrenic parents at 25-year follow-up. Arch Gen Psychiatry 54:1096-102.
18. Feighner, J. P., et al. 1972. Diagnostic criteria for use in psychiatric research. Arch Gen Psychiatry 26:57-63.
19. Freud, S., andW. Fliess. 1985. The complete letters of Sigmund Freud toWilhelm Fliess, 1887-1904, transl. and ed. J. Masson. Cambridge: Harvard Univ. Press.
20. Goldman, D. 1943. Studies on the use of refrigeration therapy in mental disease with a report of 16 cases. J Nerv Men Dis 97:162-65.
21. Goodman, B., and J. Maggio. 2008. The lobotomist. WGBH Educational Foundation. http: //www.pbs.org/wgbh/americanexperience/films/lobotomist/.
22. Grob, C. S., et al. 2011. Pilot study of psilocybin treatment for anxiety disorder in patients with advanced-stage cancer. Arch Gen Psychiatry 68:71-78.
23. Grob, G. N. 1983. Mental illness and American society, 1875-1940. Princeton: Princeton Univ. Press.
24. Guze, S. B.1970. The need for tough-mindedness in psychiatric thinking. South Med J 63: 662-71.
25. Guze, S. B. 1977. The future of psychiatry: Medicine or social science? J Nerv Ment Dis 165:225-30.
26. Guze, S. B. 1992. Why psychiatry is a branch of medicine. NewYork: Oxford Univ. Press.
27. Healy, D. 1977. The antidepressant era. Cambridge: Harvard Univ. Press.
28. Healy, D. 2002. The creation of psychopharmacology. Cambridge: Harvard Univ. Press.
29. Henderson, D., and R. E. Gillespie. 1944. Henderson and Gillespie's textbook of psychiatry. 6th ed. Oxford: Oxford Univ. Press.
30. Huang, J., et al. 2010. Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. Am J Psychiatry 167:1254-63.
31. Hyman, S. E. 2010. The diagnosis of mental disorders:The problem of reification. Annu Rev Clin Psychol 6:155-79.
32. Insel, T. R. 2010. Rethinking schizophrenia. Nature 468:187-93.
33. Insel, T.R., and R. Quirion. 2005. Psychiatry as a clinical neuroscience discipline. JAMA 294:2221-24.
34. Jerrell, J.M., R. S. McIntyre, and G. B. Black. 2012. Economic grand rounds. Economic costs of failure to monitor adverse effects of second-generation antipsychotics: An underestimated factor. Psychiatr Serv 63:202-4. doi:10.1176/appi.ps.20120p202.
35. Karam, C. S., et al. 2010. Signaling pathways in schizophrenia: Emerging targets and therapeutic pathways. Trends Pharmacol Sci 31:381-90.
36. Kendell, R. E. 1975. The role of diagnosis in psychiatry. Oxford: Blackwell.
37. Kendell, R. E., et al. 1971. Diagnostic criteria of American and British psychiatrists. Arch Gen Psychiatry 25:123-30.
38. Kendler, A. S., A. M. Gruenberg, and D. K. Kinney.1994. Independent diagnoses of adoptees and relatives as defined by DSM-III in the provincial and national samples of the Danish Adoption Study of Schizophrenia. Arch Gen Psychiatry 51:456-68.
39. Kendler, K. S., R.A. Munoz, and G. Murphy. 2010. The development of the Feighner criteria: A historical perspective. Am J Psychiatry 167:134-42.
40. Kieseppä, T., et al. 2004. High concordance of bipolar I disorder in a nationwide sample of twins. Am J Psychiatry 161:1814-21.
41. Kisely, S., et al. 2000. Why are patients prescribed psychotropic drugs by general practitioners? Results of an international study. Psychol Med 30:1217-25.
42. Kraepelin, E. 1904. Vergleichende Psychiatrie. Zentbl Nervenheilk Psychiat 27:433-37. Trans. H. Marshall.
43. Lalonde, C. D., and R. J. Van Lieshout. 2011. Treating generalized anxiety disorder with second generation antipsychotics: A systematic review and meta-analysis. J Clin Psychopharmacol 31:326-33.
44. Leslie, D. L., S. Mohamed, and R. A. Rosenheck. 2009. Off-label use of antipsychotic medications in the Department of Veterans Affairs health care system. Psychiatr Serv 60:1175-81.
45. Leslie, D. L., and R.A. Rosenheck. 2005. Pharmacotherapy and health care costs among patients with schizophrenia and newly diagnosed diabetes. Psychiatr Serv 56:803-9.
46. Lewis, S., and J. Lieberman. 2008. CATIE and CUtLASS: Can we handle the truth? Br J Psychiatry 192:161-63.
47. Lichtenstein, P., et al. 2009. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families:A population-based study. Lancet 373:234-39.
48. Linden, M., and C. Thiels. 2001. Epidemiology of prescriptions for neuroleptic drugs: Tranquilizers rather than antipsychotics. Pharmacopsychiatry 34:150-54.
49. Maher, A.R., et al. 2011. Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults:A systematic review and meta-analysis. JAMA 306:1359-69.
50. McCormmach, R. 1982. Night thoughts of a classical physicist. NewYork:Avon Books.
51. Menninger, K., M. Mayman, and P. Pruyser. 1963. The vital balance:The life process in mental health and illness. NewYork:Viking Press.
52. Milea, D., et al. 2010. Prescription patterns of antidepressants: Findings from a US claims database. Curr Med Res Opin 26:1343-53.
53. Mojtabai, R., and M. Olfson. 2008. Proportion of antidepressants prescribed without a psychiatric diagnosis is growing. Health Aff (Millwood) 30:1434-42.
54. Moncrieff, J., and D. Cohen. 2005. Rethinking models of psychotropic drug action. Psychother Psychosom 74:145-53.
55. Mula, M., S. Pini, and G. B. Cassano. 2007. The role of anticonvulsant drugs in anxiety disorders:A critical review of the evidence. J Clin Psychopharmacol 27:263-72.
56. Owen, M. J., and N. Craddock. 2009. Diagnosis of functional psychoses:Time to face the future. Lancet 373:190-91.
57. Owen, M. J., N. Craddock, and A. Jablensky. 2007. The genetic deconstruction of psychosis. Schizophr Bull 33:905-11.
58. Pagura, J., et. al. 2011. Antidepressant use in the absence of common mental disorders in the general population. J Clin Psychiatry 72:494-501.
59. Parnas, J., et al. 1993. Lifetime DSM-III diagnostic outcomes in the offspring of schizophrenic mothers: results from the Copenhagen High-Risk Study. Arch Gen Psychiatry 50:707-14.
60. Robins, E., and S. B. Guze. 1970. Establishment of diagnostic validity in psychiatric illness: Its application to schizophrenia. Am J Psychiatry 126:983-87.
61. Sakel, M. 1937. A new treatment for schizophrenia. Am J Psychiatry 93:829-41.
62. Scull, A. 1987. Desperate remedies:A Gothic tale of madness and modern medicine. Psycholog Med 17:561-77.
63. Shorter, E. 1997. A history of psychiatry. NewYork: JohnWiley.
64. Singer, D. 2009. Senator moves to stop scientific ghostwriting. NYTimes Aug. 19. http:// www.nytimes.com/2009/08/19/health/research/19ethics.html.
65. Spitzer, R., J. Endicott, and E. Robins. 1978. Research diagnostic criteria:Rationale and reliability. Arch Gen Psychiatry 35:773-82.
66. Thaker, G. K. 2012. Boundaries of the psychosis phenotype. Schizophr Bull 38:2005-6.
67. Valenstein, E. S. 1986. Great and desperate cures:The rise and decline of psychosurgery and other radical treatments for mental illness. NewYork: Basic Books.
68. Vendantam, S. 2005. Patients' diversity often discounted. Washington Post, June 26.
69. Verdoux, H., M. Tournier, and B. Begaud. 2010. Antipsychotic prescribing trends: A review of pharmaco-epidemiological studies. Acta Psychiatr Scand 121:4-10.
70. Whitaker, R. 2002. Mad in America. Cambridge: Perseus.
71. Wicks, S., A. Hjern, and C. Dalman. 2010. Social risk or genetic liability for psychosis? A study of children born in Sweden and reared by adoptive parents. Am J Psychiatry 167: 1240-46.
72. Yeh, S.R., R.A. Fricke, and D.H. Edwards. 1996. The effect of social experience on serotonergic modulation of the escape circuit of crayfish. Science 271:366-69.
73. Zarate, C. A., et al. 2006. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Arch Gen Psychiatry 63:856-64.