UbcH10 expression provides a useful tool for the prognosis and treatment of non-small cell lung cancer

Journal of Cancer Research and Clinical Oncology

Volumn 138, Issue 11, 2012, Pages 1951-1961

  Zhao, Liming ^a   Jiang, Lei ^a   Wang, Liangzhe ^a   He, Jin ^a   Yu, Hongyu ^a   Sun, Guangyuan ^a   Chen, Jiquan ^a   Xiu, Qingyu ^a   Li, Bing ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Chemosensitivity; NSCLC; RNA interference; Survival analysis; UbcH10

Indexed keywords

GEMCITABINE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME E2C; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG SENSITIVITY; EMBRYO; FEMALE; GENE EXPRESSION; GENE SILENCING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RISK FACTOR; SURVIVAL TIME;

ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; DEOXYCYTIDINE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; PACLITAXEL; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR MARKERS, BIOLOGICAL; UBIQUITIN-CONJUGATING ENZYMES;

EID: 84870404419     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1275-2     Document Type: Article

References (30)

1. Berlingieri MT, Pallante P, Sboner A, Barbareschi M, Bianco M, Ferraro A et al (2007a) UbcH10 is overexpressed in malignant breast carcinomas. Eur J Cancer 43: 2729-2735 (Pubitemid 350161847)
2. Berlingieri MT, Pallante P, Guida M, Nappi C, Masciullo V, Scambia G et al (2007b) UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomas. Oncogene 26: 2136-2140 (Pubitemid 46514746)
3. Chansky K, Sculier JP, Crowley JJ, Giroux D, Van Meerbeeck J, Goldstraw P et al (2009) The international association for the study of lung cancer staging project: prognostic factors and pathologic TNM stage in surgically managed non-small cell lung cancer. J Thorac Oncol 4: 792-801
4. Chen SM, Jiang CY, Wu JY, Liu B, Chen YJ, Hu CJ et al (2010) RNA interference-mediated silencing of UBCH10 gene inhibits colorectal cancer cell growth in vitro and in vivo. Clin Exp Pharmacol Physiol 37: 525-529
5. Chen Z, Zhang C, Wu D, Chen H, Rorick A, Zhang X et al (2011) Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth. EMBO J 30: 2405-2419
6. Chin KV, Ueda K, Pastan I, Gottesman MM (1992) Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. Science 255: 459-462
7. De Gramont A, Ganier O, Cohen-Fix O (2006) Before and after the spindle assembly checkpoint - an APC/C point of view. Cell Cycle 5: 2168-2171 (Pubitemid 44553753)
8. Fujita T, Ikeda H, Taira N, Hatoh S, Naito M, Doihara H (2009) Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation incolon cancer. BMC Cancer 9:87
9. Haupt Y, Maya R, Kazaz A (1997) Oren M. MDM2 promotes the rapid degradation of p53. Nature 387: 296-299 (Pubitemid 27220766)
10. Honda R, Tanaka H, Yasuda H (1997) Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 420: 25-27 (Pubitemid 28037193)
11. Ieta K, Ojima E, Tanaka F, Nakamura Y, Haraguchi N, Mimori K et al (2007) Identification of overexpressed genes in hepatocel-lular carcinoma, with special reference to ubiquitin-conjugating enzyme E2C gene expression. Int J Cancer 121: 33-38 (Pubitemid 46753848)
12. Jiang L, Huang CG, Lu YC, Luo C, Hu GH, Liu HM et al (2008) Expression of ubiquitin-conjugating enzyme E2C/UbcH10 in astrocytic tumors. Brain Res 1201: 161-166
13. Jiang L, Bao Y, Luo C, Hu G, Huang C, Ding X et al (2010) Knockdown of ubiquitin-conjugating enzyme E2C/UbcH10 expression by RNA interference inhibits glioma cell proliferation and enhances cell apoptosis in vitro. J Cancer Res Clin Oncol 136: 211-217
14. Kabir Z, Connolly GN, Clancy L (2008) Sex-differences in lung cancer cell-types? An epidemiologic study in Ireland. Ulster Med J 77: 31-35 (Pubitemid 351148704)
15. Kubbutat MH, Jones SN, Vousden KH (1997) Regulation of p53 stability by Mdm2. Nature 387(6630): 299-303 (Pubitemid 27220767)
16. Lai SL, Perng RP, Hwang J (2000) p53 gene status modulates the chemosensitivity of non-small cell lung cancer cells. J Biomed Sci 7: 64-70 (Pubitemid 30046573)
17. Lin J, Raoof DA, Wang Z, Lin MY, Thomas DG, Greenson JK et al (2006) Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma. Neo-plasia 8: 1062-1071 (Pubitemid 44936156)
18. Mattern J, Koomagi R, Volm K (1996) Association of vascular endothelial growth factor expression with intratumoral microvessel density and tumor cell proliferation in human epidermoid lung carcinoma. Br J Cancer 73: 931-934 (Pubitemid 26110166)
19. Okamoto Y, Ozaki T, Miyazaki K, Aoyama M, Miyazaki M, Nakagawara A (2003) UbcH10 is the cancer-related E2 ubiquitin-conjugating enzyme. Cancer Res 63: 4167-4173 (Pubitemid 36917942)
20. Pallante P, Berlingieri MT, Troncone G, Kruhoffer M, Orntoft TF, Viglietto G et al (2005) UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas. Br J Cancer 93: 464-471 (Pubitemid 43080022)
21. Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108 (Pubitemid 40372904)
22. Rape M, Kirschner MW (2004) Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry. Nature 432: 588-595 (Pubitemid 39626259)
23. Rape M, Reddy SK, Kirschner MW (2006) The processivity of multiubiquitination by the APC determines the order of substrate degradation. Cell 124: 89-103 (Pubitemid 43069312)
24. Reddy SK, Rape M, Margansky WA, Kirschner MW (2007) Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation. Nature 446: 921-925 (Pubitemid 46633168)
25. Sudo T, Nitta M, Saya H, Ueno NT (2004) Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint. Cancer Res 64: 2502-2508 (Pubitemid 38523906)
26. Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC (eds) (2004) World Health Organization classification of tumours. Pathology and genetics of tumours of the lung, pleura, thymus and heart. IARC Press, Lyon
27. Troncone G, Guerriero E, Pallante P, Berlingieri MT, Ferraro A, Del Vecchio L et al (2009) UbcH10 expression in human lymphomas. Histopathology 54: 731-740
28. Van Ree JH, Jeganathan KB, Malureanu L, van Deursen JM (2010) Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation. J Cell Biol 188: 83-100
29. Wagner KW, Sapinoso LM, El-Rifai W, Frierson HF, Butz N, Mestan J et al (2004) Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin. Oncogene 23: 6621-6629 (Pubitemid 39265525)
30. Zhang W, Kawanishi M, Miyake K, Kagawa M, Kawai N, Murao K et al (2010) Association between YKL-40 and adult primary astrocytoma. Cancer 116: 2688-2697