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Volumn 20, Issue 1, 2012, Pages

Positive effect of septimeb™ on mortality rate in severe sepsis: A novel non antibiotic strategy

Author keywords

ICU; Immunomodulation; Septimeb; Severe sepsis

Indexed keywords

GELATINASE A; IMMUNOMODULATING AGENT; INTERLEUKIN 2; PLATELET DERIVED GROWTH FACTOR; SEPTIMEB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84870398949     PISSN: 15608115     EISSN: 20082231     Source Type: Journal    
DOI: 10.1186/2008-2231-20-40     Document Type: Article
Times cited : (12)

References (45)
  • 1
    • 43049147109 scopus 로고    scopus 로고
    • Sepsis mortality prediction based on predisposition, infection and response
    • DOI 10.1007/s00134-007-0943-1
    • Sepsis mortality prediction based on predisposition, infection and response. Moreno RP, Metnitz B, Adler L, Hoechtl A, Bauer P, Metnitz PGH, Intensive Care Med 2008 34 496 504 10.1007/s00134-007-0943-1 18060541 (Pubitemid 351623030)
    • (2008) Intensive Care Medicine , vol.34 , Issue.3 , pp. 496-504
    • Moreno, R.P.1    Metnitz, B.2    Adler, L.3    Hoechtl, A.4    Bauer, P.5    Metnitz, P.G.H.6
  • 2
    • 79959825586 scopus 로고    scopus 로고
    • Severe sepsis and septic shock: A prospective population-based study in Icelandic intensive care units
    • 10.1111/j.1399-6576.2011.02437.x 21480832
    • Severe sepsis and septic shock: a prospective population-based study in Icelandic intensive care units. Vesteinsdottir E, Karason S, Sigurdsson SE, Gottfredsson M, Sigurdsson GH, Acta Anaesthesiol Scand 2011 55 722 731 10.1111/j.1399-6576.2011.02437.x 21480832
    • (2011) Acta Anaesthesiol Scand , vol.55 , pp. 722-731
    • Vesteinsdottir, E.1    Karason, S.2    Sigurdsson, S.E.3    Gottfredsson, M.4    Sigurdsson, G.H.5
  • 3
    • 1442315460 scopus 로고    scopus 로고
    • Physiopathology of severe sepsis
    • discussion 269 10.1016/S0755-4982(04)98551-X 15029017
    • [Physiopathology of severe sepsis]. Caille V, Bossi P, Grimaldi D, Vieillard-Baro A, Presse Med 2004 33 256 261 discussion 269 10.1016/S0755- 4982(04)98551-X 15029017
    • (2004) Presse Med , vol.33 , pp. 256-261
    • Caille, V.1    Bossi, P.2    Grimaldi, D.3    Vieillard-Baro, A.4
  • 5
    • 77955621236 scopus 로고    scopus 로고
    • Place of iron chelators like desferrioxamine and deferasirox in management of hyperoxia-induced lung injury: A systematic review
    • Place of iron chelators like desferrioxamine and deferasirox in management of hyperoxia-induced lung injury: A systematic review. Mousavi S, Mojtahedzadeh M, Abdollahi M, Int J Pharmacol 2010 6 326 337
    • (2010) Int J Pharmacol , vol.6 , pp. 326-337
    • Mousavi, S.1    Mojtahedzadeh, M.2    Abdollahi, M.3
  • 7
    • 36348948474 scopus 로고    scopus 로고
    • Improvement by N-acetylcysteine of acute respiratory distress syndrome through increasing intracellular glutathione, and extracellular thiol molecules and anti-oxidant power: Evidence for underlying toxicological mechanisms
    • DOI 10.1177/0960327107083452
    • Improvement by N-acetylcysteine of acute respiratory distress syndrome through increasing intracellular glutathione, and extracellular thiol molecules and anti-oxidant power: evidence for underlying toxicological mechanisms. Soltan-Sharifi MS, Mojtahedzadeh M, Najafi A, Khajavi MR, Rouini MR, Moradi M, Mohammadirad A, Abdollahi M, Hum Exp Toxicol 2007 26 697 703 10.1177/0960327107083452 17984140 (Pubitemid 350157338)
    • (2007) Human and Experimental Toxicology , vol.26 , Issue.9 , pp. 697-703
    • Soltan-Sharifi, M.S.1    Mojtahedzadeh, M.2    Najafi, A.3    Khajavi, M.R.4    Rouini, M.R.5    Moradi, M.6    Mohammadirad, A.7    Abdollahi, M.8
  • 8
    • 0033969341 scopus 로고    scopus 로고
    • Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
    • DOI 10.1086/315214
    • Pro-versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options. Gogos CA, Drosou E, Bassaris HP, Skoutelis A, J Infect Dis 2000 181 176 180 10.1086/315214 10608764 (Pubitemid 30049046)
    • (2000) Journal of Infectious Diseases , vol.181 , Issue.1 , pp. 176-180
    • Gogos, C.A.1    Drosou, E.2    Bassaris, H.P.3    Skoutelis, A.4
  • 11
    • 11144317893 scopus 로고    scopus 로고
    • Corticosteroid therapy in patients with severe sepsis and septic shock
    • DOI 10.1055/s-2004-860985
    • Corticosteroid therapy in patients with severe sepsis and septic shock. Keh D, Goodman S, Sprung CL, Semin Respir Crit Care Med 2004 25 713 719 10.1055/s-2004-860985 16088513 (Pubitemid 40041591)
    • (2004) Seminars in Respiratory and Critical Care Medicine , vol.25 , Issue.6 , pp. 713-719
    • Keh, D.1    Goodman, S.2    Sprung, C.L.3
  • 12
    • 70350738441 scopus 로고    scopus 로고
    • Corticosteroid therapy for severe sepsis and septic shock
    • author reply 1644-1645 19843895
    • Corticosteroid therapy for severe sepsis and septic shock. Minneci PC, Deans KJ, Natanson C, JAMA 2009 302 1643 author reply 1644-1645 19843895
    • (2009) JAMA , vol.302 , pp. 1643
    • Minneci, P.C.1    Deans, K.J.2    Natanson, C.3
  • 17
    • 0000918029 scopus 로고    scopus 로고
    • Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis
    • Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis. Vincent JL, Spapen H, Bakker J, Webster NR, Curtis L, Crit Care Med 2000 28 638 642 10.1097/00003246-200003000-00006 10752807 (Pubitemid 30174255)
    • (2000) Critical Care Medicine , vol.28 , Issue.3 , pp. 638-642
    • Vincent, J.-L.1    Spapen, H.2    Bakker, J.3    Webster, N.R.4    Curtis, L.5
  • 18
    • 33845954738 scopus 로고    scopus 로고
    • Selenium in Intensive Care (SIC): Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock
    • DOI 10.1097/01.CCM.0000251124.83436.0E, PII 0000324620070100000019
    • Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock. Angstwurm MW, Engelmann L, Zimmermann T, Lehmann C, Spes CH, Abel P, Strauss R, Meier-Hellmann A, Insel R, Radke J, et al. Crit Care Med 2007 35 118 126 10.1097/01.CCM. 0000251124.83436.0E 17095947 (Pubitemid 46035686)
    • (2007) Critical Care Medicine , vol.35 , Issue.1 , pp. 118-126
    • Angstwurm, M.W.A.1    Engelmann, L.2    Zimmermann, T.3    Lehmann, C.4    Spes, C.H.5    Abel, P.6    Strauss, R.7    Meier-Hellmann, A.8    Insel, R.9    Radke, J.10    Schuttler, J.11    Gartner, R.12
  • 19
    • 79955568941 scopus 로고    scopus 로고
    • High-dose selenium substitution in sepsis: A prospective randomized clinical trial
    • 10.1007/s00134-011-2153-0 21347869
    • High-dose selenium substitution in sepsis: a prospective randomized clinical trial. Valenta J, Brodska H, Drabek T, Hendl J, Kazda A, Intensive Care Med 2011 37 808 815 10.1007/s00134-011-2153-0 21347869
    • (2011) Intensive Care Med , vol.37 , pp. 808-815
    • Valenta, J.1    Brodska, H.2    Drabek, T.3    Hendl, J.4    Kazda, A.5
  • 20
    • 77954828961 scopus 로고    scopus 로고
    • Comparison the inflammatory effects of early supplemental parenteral nutrition plus enteral nutrition versus enteral nutrition alone in critically ill patients
    • 22615602
    • Comparison the inflammatory effects of early supplemental parenteral nutrition plus enteral nutrition versus enteral nutrition alone in critically ill patients. Abrishami RA A, Abdollahi M, Moosivand A, Khalili H, Najafi A, Gholami K, Hamishehkar H, Yazdi AP, Mojtahedzadeh M, daru 2010 18 103 106 22615602
    • (2010) Daru , vol.18 , pp. 103-106
    • Abrishami Ra, A.1    Abdollahi, M.2    Moosivand, A.3    Khalili, H.4    Najafi, A.5    Gholami, K.6    Hamishehkar, H.7    Yazdi, A.P.8    Mojtahedzadeh, M.9
  • 21
    • 0037248228 scopus 로고    scopus 로고
    • Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis
    • 10.1097/00003246-200301001-00012 12544981
    • Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis. Bernard GR, Crit Care Med 2003 31 85 93 10.1097/00003246-200301001-00012 12544981
    • (2003) Crit Care Med , vol.31 , pp. 1985-1993
    • Bernard, G.R.1
  • 22
    • 0028707581 scopus 로고
    • Initial studies on the administration of C1-esterase inhibitor to patients with septic shock or with a vascular leak syndrome induced by interleukin-2 therapy
    • 7831367
    • Initial studies on the administration of C1-esterase inhibitor to patients with septic shock or with a vascular leak syndrome induced by interleukin-2 therapy. Hack CE, Ogilvie AC, Eisele B, Jansen PM, Wagstaff J, Thijs LG, Prog Clin Biol Res 1994 388 335 357 7831367
    • (1994) Prog Clin Biol Res , vol.388 , pp. 335-357
    • Hack, C.E.1    Ogilvie, A.C.2    Eisele, B.3    Jansen, P.M.4    Wagstaff, J.5    Thijs, L.G.6
  • 23
    • 77957852137 scopus 로고    scopus 로고
    • Evaluation of the effects of pulse high-volume hemofiltration in patients with severe sepsis: A preliminary study
    • 20872345
    • Evaluation of the effects of pulse high-volume hemofiltration in patients with severe sepsis: a preliminary study. Peng Z, Pai P, Han-Min W, Jun Z, Hong-Bao L, Rong L, Chen H, Int J Artif Organs 2010 33 505 511 20872345
    • (2010) Int J Artif Organs , vol.33 , pp. 505-511
    • Peng, Z.1    Pai, P.2    Han-Min, W.3    Jun, Z.4    Hong-Bao, L.5    Rong, L.6    Chen, H.7
  • 24
    • 16844378307 scopus 로고    scopus 로고
    • Botanical immunodrugs: Scope and opportunities
    • DOI 10.1016/S1359-6446(04)03357-4, PII S1359644604033574
    • Botanical immunodrugs: scope and opportunities. Patwardhan B, Gautam M, Drug Discov Today 2005 10 495 502 10.1016/S1359-6446(04)03357-4 15809195 (Pubitemid 40487492)
    • (2005) Drug Discovery Today , vol.10 , Issue.7 , pp. 495-502
    • Patwardhan, B.1    Gautam, M.2
  • 26
    • 80755185245 scopus 로고    scopus 로고
    • Etarud (IMODTM) as a multiherbal drug with promising benefits in animal and human studies: A comprehensive review of biochemical and cellular evidences
    • 10.3923/ajava.2011.1185.1192
    • etarud (IMODTM) as a multiherbal drug with promising benefits in animal and human studies: A comprehensive review of biochemical and cellular evidences. Mohammadirad AK-KH, Gharibdoost F, Abdollahi M, Asian J Anim Vet Adv 2011 6 1185 1192 10.3923/ajava.2011.1185.1192
    • (2011) Asian J Anim Vet Adv , vol.6 , pp. 1185-1192
    • Mohammadirad, A.-K.1    Gharibdoost, F.2    Abdollahi, M.3
  • 27
    • 84870410034 scopus 로고    scopus 로고
    • Evaluation of safety and efficacy of IMOD inb patients with HIV/AIDS
    • Evaluation of safety and efficacy of IMOD inb patients with HIV/AIDS. Mohraz M, S B, F M, K K, c R, Iranian J Allergy Asthma Immunol 2007 6 10
    • (2007) Iranian J Allergy Asthma Immunol , vol.6 , pp. 10
    • Mohraz, M.1
  • 29
    • 84870477033 scopus 로고    scopus 로고
    • Aphase i clinical trial to determine the maximum tolerated dose and toxicity of IMOD in HIV infected asymptomatic patiets in Iran
    • Aphase I clinical trial to determine the maximum tolerated dose and toxicity of IMOD in HIV infected asymptomatic patiets in Iran. Keirandish PMM, khorram Khorshid H, Heshmat R, Gharibdust F, Iranian J Allergy,Asthma Immunol 2007 6 5
    • (2007) Iranian J Allergy,Asthma Immunol , vol.6 , pp. 5
    • Keirandish, P.M.M.1    Khorram Khorshid, H.2    Heshmat, R.3    Gharibdust, F.4
  • 31
    • 84983032240 scopus 로고    scopus 로고
    • The Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
    • 18304010
    • The Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Hicks P, Cooper DJ, Crit Care Resusc 2008 10 8 18304010
    • (2008) Crit Care Resusc , vol.10 , pp. 8
    • Hicks, P.1    Cooper, D.J.2
  • 32
    • 34247338128 scopus 로고    scopus 로고
    • Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: A trend analysis from 1993 to 2003
    • DOI 10.1097/01.CCM.0000261890.41311.E9
    • Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Dombrovskiy VY, Martin AA, Sunderram J, Paz HL, Crit Care Med 2007 35 1244 1250 10.1097/01.CCM. 0000261890.41311.E9 17414736 (Pubitemid 46642649)
    • (2007) Critical Care Medicine , vol.35 , Issue.5 , pp. 1244-1250
    • Dombrovskiy, V.Y.1    Martin, A.A.2    Sunderram, J.3    Paz, H.L.4
  • 33
    • 0036389976 scopus 로고    scopus 로고
    • Plasmapheresis in severe sepsis and septic shock: A prospective, randomised, controlled trial
    • 10.1007/s00134-002-1410-7 12373468
    • Plasmapheresis in severe sepsis and septic shock: a prospective, randomised, controlled trial. Busund R, Koukline V, Utrobin U, Nedashkovsky E, Intensive care medicine 2002 28 1434 1439 10.1007/s00134-002-1410-7 12373468
    • (2002) Intensive Care Medicine , vol.28 , pp. 1434-1439
    • Busund, R.1    Koukline, V.2    Utrobin, U.3    Nedashkovsky, E.4
  • 35
    • 8544284118 scopus 로고    scopus 로고
    • Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial*
    • 15640632
    • Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial*. Laterre PF, Levy H, Clermont G, Ball DE, Garg R, Nelson DR, Dhainaut JF, Angus DC, Critical care medicine 2004 32 2207 15640632
    • (2004) Critical Care Medicine , vol.32 , pp. 2207
    • Laterre, P.F.1    Levy, H.2    Clermont, G.3    Ball, D.E.4    Garg, R.5    Nelson, D.R.6    Dhainaut, J.F.7    Angus, D.C.8
  • 36
    • 27644501881 scopus 로고    scopus 로고
    • A meta-analysis of controlled trials of recombinant human activated protein C therapy in patients with sepsis
    • DOI 10.1186/1471-227X-5-7
    • A meta-analysis of controlled trials of recombinant human activated protein C therapy in patients with sepsis. Wiedermann C, Kaneider N, BMC emergency medicine 2005 5 7 10.1186/1471-227X-5-7 16225672 (Pubitemid 41554965)
    • (2005) BMC Emergency Medicine , vol.5 , pp. 7
    • Wiedermann, C.J.1    Kaneider, N.C.2
  • 38
    • 42649094198 scopus 로고    scopus 로고
    • A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1
    • DOI 10.1371/journal.pone.0001153
    • A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1. Li W, Ashok M, Li J, Yang H, Sama AE, Wang H, PLoS One 2007 2 1153 10.1371/journal.pone.0001153 17987129 (Pubitemid 351597638)
    • (2007) PLoS ONE , vol.2 , Issue.11
    • Li, W.1    Ashok, M.2    Li, J.3    Yang, H.4    Sama, A.E.5    Wang, H.6
  • 39
    • 34548040244 scopus 로고    scopus 로고
    • The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis
    • DOI 10.1097/shk.0b013e3180485823, PII 0002438220070900000015
    • The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis. Wheeler DS, Lahni PM, Hake PW, Denenberg AG, Wong HR, Snead C, Catravas JD, Zingarelli B, Shock 2007 28 353 359 10.1097/shk.0b013e3180485823 17545942 (Pubitemid 47282028)
    • (2007) Shock , vol.28 , Issue.3 , pp. 353-359
    • Wheeler, D.S.1    Lahni, P.M.2    Hake, P.W.3    Denenberg, A.G.4    Wong, H.R.5    Snead, C.6    Catravas, J.D.7    Zingarelli, B.8
  • 41
    • 80755171880 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-alpha and nitrosative/oxidative stresses by Setarud (IMOD®); A molecular mechanism of protection against letrozole-induced polycystic ovary
    • Inhibition of tumor necrosis factor-alpha and nitrosative/oxidative stresses by Setarud (IMOD®); a molecular mechanism of protection against letrozole-induced polycystic ovary. Rezvanfar MA, Ahmadi A, Baeeri M, Abdollahi M, Toxicology Letters 2011 205 246
    • (2011) Toxicology Letters , vol.205 , pp. 19246
    • Rezvanfar, M.A.1    Ahmadi, A.2    Baeeri, M.3    Abdollahi, M.4
  • 42
    • 0029972559 scopus 로고    scopus 로고
    • PATHOPHYSIOLOGIE DER SEPSIS. AKTUELLE KONZEPTE
    • DOI 10.1007/s001010050266
    • [The physiopathology of sepsis. Current concepts]. Bauer M, Anaesthesist 1996 45 312 322 10.1007/s001010050266 8702048 (Pubitemid 26151575)
    • (1996) Anaesthesist , vol.45 , Issue.4 , pp. 312-322
    • Bauer, M.1
  • 43
    • 36048933359 scopus 로고    scopus 로고
    • Hemodynamic optimization of sepsis-induced tissue hypoperfusion
    • 17352796
    • Hemodynamic optimization of sepsis-induced tissue hypoperfusion. Cavazzoni SLZ, Dellinger RP, Critical Care 2006 10 2 17352796
    • (2006) Critical Care , vol.10 , pp. 192
    • Cavazzoni, S.L.Z.1    Dellinger, R.P.2
  • 44
    • 34250733466 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, bioenergetic impairment, and metabolic down-regulation in sepsis
    • DOI 10.1097/01.shk.0000235089.30550.2d
    • Mitochondrial dysfunction, bioenergenic impairment, and metabolic down-regulation in sepsis. Levy R, shock 2007 28 24 28 10.1097/01.shk. 0000235089.30550.2d 17483747 (Pubitemid 46956458)
    • (2007) Shock , vol.28 , Issue.1 , pp. 24-28
    • Levy, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.