Identification of decorin derived peptides with a zinc dependent anti-myostatin activity

Neuromuscular Disorders

Volumn 22, Issue 12, 2012, Pages 1057-1068

  Guiraud, Simon ^a,b   van Wittenberghe, Laetitia ^a   Georger, Christophe ^a   Scherman, Daniel ^b   Kichler, Antoine ^a,b  

^a GÉNÉTHON   (France)

^b Centre National de la Recherche Scientifique   (France)

Author keywords

Decorin; Mdx mouse; Muscular dystrophy; Myostatin; Skeletal muscle; Small leucine rich proteoglycans

Indexed keywords

ALPHA SARCOGLYCAN; ASPARTYLASPARAGINYLPROLYLLEUCYLISOLEUCYLSERYLMETHIONYLCYSTEINYLPROLYLTRY PTOPHANYLARGINYLCYSTEINYLGLUTAMINYLCYSTEINYLHISTIDYLLEUCYLARGINYLVALYLVA LYLGLUTAMINYLCYSTEINYLSERYLASPARTYLLEUCYLGLYCYLLEUCYLASPARTYLLYSYLVALYLP ROLINE; ASPARTYLGLUTAMYLALANYLSERYLGLYCYLISOLEUCYLISOLEUCYLPROYLYTYROSYLASPARTYL PROLYLASPARTYLASPARAGINYLPROLYLLEUCYLISOLEUCYLSERYLMETHIONYLCYSTEINYLPRO LYLTRYPTOPHANYLARGINYLCYSTEINYLGLUTAMINYLCYSTEINYLHISTIDYLLEUCYLARGINYLV ALYLVALYLGLUTAMINE; DECORIN; LEUCINE; MYOSTATIN; PROTEOGLYCAN; RECOMBINANT DECORIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG PROTEIN BINDING; EMBRYO; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUSCULAR DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SYNTHESIS INHIBITION; STRUCTURE ACTIVITY RELATION; TREATMENT OUTCOME;

ANIMALS; DECORIN; EXTRACELLULAR MATRIX PROTEINS; MICE; MICE, INBRED MDX; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR DISEASES; MYOSTATIN; PEPTIDES; PROTEIN BINDING; PROTEOGLYCANS; ZINC;

EID: 84870393637     PISSN: 09608966     EISSN: 18732364     Source Type: Journal    
DOI: 10.1016/j.nmd.2012.07.002     Document Type: Article

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