메뉴 건너뛰기




Volumn 14, Issue 5, 2012, Pages

Biologic adjuvants for fracture healing

Author keywords

[No Author keywords available]

Indexed keywords

ANABOLIC AGENT; BIOLOGICAL PRODUCT; CALCIUM; CALCIUM PHOSPHATE; COLECALCIFEROL; COLLAGEN SPONGE; DICKKOPF 1 PROTEIN; FIBROBLAST GROWTH FACTOR 10; PARATHYROID HORMONE; PARATHYROID HORMONE[1-34]; PLACEBO; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR BB; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT FIBROBLAST GROWTH FACTOR; RECOMBINANT OSTEOGENIC PROTEIN 1; RECOMBINANT PARATHYROID HORMONE; RECOMBINANT PLATELET DERIVED GROWTH FACTOR; RECOMBINANT PLATELET DERIVED GROWTH FACTOR BB; REPIFERMIN; SCLEROSTIN; BONE MORPHOGENETIC PROTEIN;

EID: 84870391273     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4053     Document Type: Review
Times cited : (34)

References (90)
  • 1
    • 33947305613 scopus 로고    scopus 로고
    • New technologies for the enhancement of skeletal repair
    • Axelrad TW, Kakar S, Einhorn TA. New technologies for the enhancement of skeletal repair. Injury 2007, 38(Suppl 1):S49-62.
    • (2007) Injury , vol.38 , Issue.SUPPL. 1
    • Axelrad, T.W.1    Kakar, S.2    Einhorn, T.A.3
  • 2
    • 0031056651 scopus 로고    scopus 로고
    • The economics of treating tibia fractures. The cost of delayed unions
    • Heckman JD, Sarasohn-Kahn J. The economics of treating tibia fractures. The cost of delayed unions. Bull Hosp Jt Dis 1997, 56:63-72.
    • (1997) Bull Hosp Jt Dis , vol.56 , pp. 63-72
    • Heckman, J.D.1    Sarasohn-Kahn, J.2
  • 3
    • 0033770531 scopus 로고    scopus 로고
    • Orthopaedic gene therapy. Fracture healing and other nongenetic problems of bone
    • Lieberman JR. Orthopaedic gene therapy. Fracture healing and other nongenetic problems of bone. Clin Orthop Relat Res 2000, (379 Suppl):S156-158.
    • (2000) Clin Orthop Relat Res , Issue.379 SUPPL
    • Lieberman, J.R.1
  • 4
    • 40149095754 scopus 로고    scopus 로고
    • Gene therapy applications for fracture-healing
    • Carofino BC, Lieberman JR. Gene therapy applications for fracture-healing. J Bone Joint Surg Am 2008, 90(Suppl 1):99-110.
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.SUPPL. 1 , pp. 99-110
    • Carofino, B.C.1    Lieberman, J.R.2
  • 6
    • 0036166393 scopus 로고    scopus 로고
    • Connective tissue progenitors: practical concepts for clinical applications
    • Muschler GF, Midura RJ. Connective tissue progenitors: practical concepts for clinical applications. Clin Orthop Relat Res 2002, (395):66-80.
    • (2002) Clin Orthop Relat Res , Issue.395 , pp. 66-80
    • Muschler, G.F.1    Midura, R.J.2
  • 7
    • 78651082309 scopus 로고    scopus 로고
    • Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair
    • 10.1002/stem.546, 3125598, 20960512
    • Khosla S, Westendorf JJ, Modder UI. Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair. Stem Cells 2010, 28:2124-2128. 10.1002/stem.546, 3125598, 20960512.
    • (2010) Stem Cells , vol.28 , pp. 2124-2128
    • Khosla, S.1    Westendorf, J.J.2    Modder, U.I.3
  • 8
    • 33847617021 scopus 로고    scopus 로고
    • From the laboratory bench to the patient's bedside: an update on clinical trials with mesenchymal stem cells
    • 10.1002/jcp.20959, 17226788
    • Giordano A, Galderisi U, Marino IR. From the laboratory bench to the patient's bedside: an update on clinical trials with mesenchymal stem cells. J Cell Physiol 2007, 211:27-35. 10.1002/jcp.20959, 17226788.
    • (2007) J Cell Physiol , vol.211 , pp. 27-35
    • Giordano, A.1    Galderisi, U.2    Marino, I.R.3
  • 9
    • 0014261390 scopus 로고
    • Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissues
    • 10.1097/00007890-196803000-00009, 5654088
    • Friedenstein AJ, Petrakova KV, Kurolesova AI, Frolova GP. Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissues. Transplantation 1968, 6:230-247. 10.1097/00007890-196803000-00009, 5654088.
    • (1968) Transplantation , vol.6 , pp. 230-247
    • Friedenstein, A.J.1    Petrakova, K.V.2    Kurolesova, A.I.3    Frolova, G.P.4
  • 10
    • 36348930963 scopus 로고    scopus 로고
    • Successful treatment of refractory tibial nonunion using calcium sulphate and bone marrow stromal cell implantation
    • 10.1302/0301-620X.89B10.19103, 17957083
    • Bajada S, Harrison PE, Ashton BA, Cassar-Pullicino VN, Ashammakhi N, Richardson JB. Successful treatment of refractory tibial nonunion using calcium sulphate and bone marrow stromal cell implantation. J Bone Joint Surg Br 2007, 89:1382-1386. 10.1302/0301-620X.89B10.19103, 17957083.
    • (2007) J Bone Joint Surg Br , vol.89 , pp. 1382-1386
    • Bajada, S.1    Harrison, P.E.2    Ashton, B.A.3    Cassar-Pullicino, V.N.4    Ashammakhi, N.5    Richardson, J.B.6
  • 11
    • 34249889868 scopus 로고    scopus 로고
    • Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study
    • 10.1089/ten.2006.0271, 17484701
    • Marcacci M, Kon E, Moukhachev V, Lavroukov A, Kutepov S, Quarto R, Mastrogiacomo M, Cancedda R. Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study. Tissue Eng 2007, 13:947-955. 10.1089/ten.2006.0271, 17484701.
    • (2007) Tissue Eng , vol.13 , pp. 947-955
    • Marcacci, M.1    Kon, E.2    Moukhachev, V.3    Lavroukov, A.4    Kutepov, S.5    Quarto, R.6    Mastrogiacomo, M.7    Cancedda, R.8
  • 14
    • 40149086690 scopus 로고    scopus 로고
    • Nonunions and the potential of stem cells in fracture-healing
    • Tseng SS, Lee MA, Reddi AH. Nonunions and the potential of stem cells in fracture-healing. J Bone Joint Surg Am 2008, 90(Suppl 1):92-98.
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.SUPPL. 1 , pp. 92-98
    • Tseng, S.S.1    Lee, M.A.2    Reddi, A.H.3
  • 15
    • 10044234031 scopus 로고    scopus 로고
    • Percutaneous bone marrow grafting for the treatment of tibial non-union
    • 10.1016/j.injury.2004.01.009, 15589942
    • Goel A, Sangwan SS, Siwach RC, Ali AM. Percutaneous bone marrow grafting for the treatment of tibial non-union. Injury 2005, 36:203-206. 10.1016/j.injury.2004.01.009, 15589942.
    • (2005) Injury , vol.36 , pp. 203-206
    • Goel, A.1    Sangwan, S.S.2    Siwach, R.C.3    Ali, A.M.4
  • 16
    • 34249872286 scopus 로고    scopus 로고
    • Percutaneous autologous bone-marrow grafting for nonunions. Surgical technique
    • Hernigou P, Mathieu G, Poignard A, Manicom O, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions. Surgical technique. J Bone Joint Surg Am 2006, 88(Suppl 1 Pt 2):322-327.
    • (2006) J Bone Joint Surg Am , vol.88 , Issue.SSUPPL. 1 PART 2 , pp. 322-327
    • Hernigou, P.1    Mathieu, G.2    Poignard, A.3    Manicom, O.4    Beaujean, F.5    Rouard, H.6
  • 18
    • 0026356843 scopus 로고
    • Autologous marrow injection as a substitute for operative grafting of tibial nonunions
    • Connolly JF, Guse R, Tiedeman J, Dehne R. Autologous marrow injection as a substitute for operative grafting of tibial nonunions. Clin Orthop Relat Res 1991, (266):259-270.
    • (1991) Clin Orthop Relat Res , Issue.266 , pp. 259-270
    • Connolly, J.F.1    Guse, R.2    Tiedeman, J.3    Dehne, R.4
  • 19
    • 0031734665 scopus 로고    scopus 로고
    • Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis
    • Connolly JF. Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis. Clin Orthop Relat Res 1998, (355 Suppl):S257-266.
    • (1998) Clin Orthop Relat Res , Issue.355 SUPPL
    • Connolly, J.F.1
  • 20
    • 33847346783 scopus 로고    scopus 로고
    • Percutaneous autologus bone marrow injection in the treatment of delayed or nonunion
    • 10.4103/0019-5413.30529, 2981899, 21124686
    • Bhargava R, Sankhla S, Gupta A, Changani R, Gagal K. Percutaneous autologus bone marrow injection in the treatment of delayed or nonunion. Indian J Orthop 2007, 41:67-71. 10.4103/0019-5413.30529, 2981899, 21124686.
    • (2007) Indian J Orthop , vol.41 , pp. 67-71
    • Bhargava, R.1    Sankhla, S.2    Gupta, A.3    Changani, R.4    Gagal, K.5
  • 21
    • 0027683390 scopus 로고
    • Autologous marrow injection in the treatment of delayed and non-union in long bones
    • Sim R, Liang TS, Tay BK. Autologous marrow injection in the treatment of delayed and non-union in long bones. Singapore Med J 1993, 34:412-417.
    • (1993) Singapore Med J , vol.34 , pp. 412-417
    • Sim, R.1    Liang, T.S.2    Tay, B.K.3
  • 22
    • 0027753808 scopus 로고
    • Percutaneous autogenous bone marrow grafting in 20 cases of ununited fracture
    • 10.3109/17453679308994595, 8291415
    • Garg NK, Gaur S, Sharma S. Percutaneous autogenous bone marrow grafting in 20 cases of ununited fracture. Acta Orthop Scand 1993, 64:671-672. 10.3109/17453679308994595, 8291415.
    • (1993) Acta Orthop Scand , vol.64 , pp. 671-672
    • Garg, N.K.1    Gaur, S.2    Sharma, S.3
  • 23
    • 0036080678 scopus 로고    scopus 로고
    • Percutaneous bone grafting in the treatment of the delayed union and non-union of tibial fractures
    • 10.1016/S0020-1383(01)00075-4, 12084640
    • Kettunen J, Makela EA, Turunen V, Suomalainen O, Partanen K. Percutaneous bone grafting in the treatment of the delayed union and non-union of tibial fractures. Injury 2002, 33:239-245. 10.1016/S0020-1383(01)00075-4, 12084640.
    • (2002) Injury , vol.33 , pp. 239-245
    • Kettunen, J.1    Makela, E.A.2    Turunen, V.3    Suomalainen, O.4    Partanen, K.5
  • 24
    • 3042852166 scopus 로고    scopus 로고
    • A prospective randomized trial of percutaneous marrow injection in a series of closed fresh tibial fractures
    • 10.1007/s00264-004-0547-0, 3474489, 15007562
    • Khanal GP, Garg M, Singh GK. A prospective randomized trial of percutaneous marrow injection in a series of closed fresh tibial fractures. Int Orthop 2004, 28:167-170. 10.1007/s00264-004-0547-0, 3474489, 15007562.
    • (2004) Int Orthop , vol.28 , pp. 167-170
    • Khanal, G.P.1    Garg, M.2    Singh, G.K.3
  • 25
    • 21444445838 scopus 로고    scopus 로고
    • Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells
    • 10.2106/JBJS.D.02215, 15995108
    • Hernigou P, Poignard A, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am 2005, 87:1430-1437. 10.2106/JBJS.D.02215, 15995108.
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 1430-1437
    • Hernigou, P.1    Poignard, A.2    Beaujean, F.3    Rouard, H.4
  • 26
    • 70350046985 scopus 로고    scopus 로고
    • Mesenchymal stem cell concentration and bone repair: potential pitfalls from bench to bedside
    • 10.2106/JBJS.H.00303, 19411455
    • Cuomo AV, Virk M, Petrigliano F, Morgan EF, Lieberman JR. Mesenchymal stem cell concentration and bone repair: potential pitfalls from bench to bedside. J Bone Joint Surg Am 2009, 91:1073-1083. 10.2106/JBJS.H.00303, 19411455.
    • (2009) J Bone Joint Surg Am , vol.91 , pp. 1073-1083
    • Cuomo, A.V.1    Virk, M.2    Petrigliano, F.3    Morgan, E.F.4    Lieberman, J.R.5
  • 27
    • 0030702126 scopus 로고    scopus 로고
    • Aspiration to obtain osteoblast progenitor cells from human bone marrow: the influence of aspiration volume
    • Muschler GF, Boehm C, Easley K. Aspiration to obtain osteoblast progenitor cells from human bone marrow: the influence of aspiration volume. J Bone Joint Surg Am 1997, 79:1699-1709.
    • (1997) J Bone Joint Surg Am , vol.79 , pp. 1699-1709
    • Muschler, G.F.1    Boehm, C.2    Easley, K.3
  • 28
    • 34247580964 scopus 로고    scopus 로고
    • Number and proliferative capacity of human mesenchymal stem cells are modulated positively in multiple trauma patients and negatively in atrophic nonunions
    • 10.1007/s00223-007-9020-6, 17431529
    • Seebach C, Henrich D, Tewksbury R, Wilhelm K, Marzi I. Number and proliferative capacity of human mesenchymal stem cells are modulated positively in multiple trauma patients and negatively in atrophic nonunions. Calcif Tissue Int 2007, 80:294-300. 10.1007/s00223-007-9020-6, 17431529.
    • (2007) Calcif Tissue Int , vol.80 , pp. 294-300
    • Seebach, C.1    Henrich, D.2    Tewksbury, R.3    Wilhelm, K.4    Marzi, I.5
  • 29
    • 0037853122 scopus 로고    scopus 로고
    • Percutaneous treatment of long bone nonunions: the use of autologous bone marrow and allograft bone matrix
    • Wilkins RM, Chimenti BT, Rifkin RM. Percutaneous treatment of long bone nonunions: the use of autologous bone marrow and allograft bone matrix. Orthopedics 2003, 26(5 Suppl):s549-554.
    • (2003) Orthopedics , vol.26 , Issue.5 SUPPL
    • Wilkins, R.M.1    Chimenti, B.T.2    Rifkin, R.M.3
  • 30
    • 47249162468 scopus 로고    scopus 로고
    • Concentration of bone marrow aspirate for osteogenic repair using simple centrifugal methods
    • 10.1080/17453670710015382, 18626810
    • Sakai S, Mishima H, Ishii T, Akaogi H, Yoshioka T, Uemura T, Ochiai N. Concentration of bone marrow aspirate for osteogenic repair using simple centrifugal methods. Acta Orthop 2008, 79:445-448. 10.1080/17453670710015382, 18626810.
    • (2008) Acta Orthop , vol.79 , pp. 445-448
    • Sakai, S.1    Mishima, H.2    Ishii, T.3    Akaogi, H.4    Yoshioka, T.5    Uemura, T.6    Ochiai, N.7
  • 31
    • 12344291865 scopus 로고    scopus 로고
    • Bone morphogenetic proteins
    • 10.1080/08977190412331279890, 15621726
    • Chen D, Zhao M, Mundy GR. Bone morphogenetic proteins. Growth Factors 2004, 22:233-241. 10.1080/08977190412331279890, 15621726.
    • (2004) Growth Factors , vol.22 , pp. 233-241
    • Chen, D.1    Zhao, M.2    Mundy, G.R.3
  • 32
    • 0036599845 scopus 로고    scopus 로고
    • The role of growth factors in the repair of bone. Biology and clinical applications
    • Lieberman JR, Daluiski A, Einhorn TA. The role of growth factors in the repair of bone. Biology and clinical applications. J Bone Joint Surg Am 2002, 84-A:1032-1044.
    • (2002) J Bone Joint Surg Am , vol.84 A , pp. 1032-1044
    • Lieberman, J.R.1    Daluiski, A.2    Einhorn, T.A.3
  • 33
    • 34250019537 scopus 로고
    • Bone: formation by autoinduction
    • 10.1126/science.150.3698.893, 5319761
    • Urist MR. Bone: formation by autoinduction. Science 1965, 150:893-899. 10.1126/science.150.3698.893, 5319761.
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, M.R.1
  • 34
    • 79151473137 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: a critical review
    • 10.1016/j.cellsig.2010.10.003, 20959140
    • Bragdon B, Moseychuk O, Saldanha S, King D, Julian J, Nohe A. Bone morphogenetic proteins: a critical review. Cell Signal 2011, 23:609-620. 10.1016/j.cellsig.2010.10.003, 20959140.
    • (2011) Cell Signal , vol.23 , pp. 609-620
    • Bragdon, B.1    Moseychuk, O.2    Saldanha, S.3    King, D.4    Julian, J.5    Nohe, A.6
  • 35
    • 0242668869 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, their antagonists, and the skeleton
    • 10.1210/er.2002-0023, 12700180
    • Canalis E, Economides AN, Gazzerro E. Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr Rev 2003, 24:218-235. 10.1210/er.2002-0023, 12700180.
    • (2003) Endocr Rev , vol.24 , pp. 218-235
    • Canalis, E.1    Economides, A.N.2    Gazzerro, E.3
  • 37
    • 33745713060 scopus 로고    scopus 로고
    • Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial
    • 10.2106/JBJS.E.00381, 16818967
    • Jones AL, Bucholz RW, Bosse MJ, Mirza SK, Lyon TR, Webb LX, Pollak AN, Golden JD, Valentin-Opran A. Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial. J Bone Joint Surg Am 2006, 88:1431-1441. 10.2106/JBJS.E.00381, 16818967.
    • (2006) J Bone Joint Surg Am , vol.88 , pp. 1431-1441
    • Jones, A.L.1    Bucholz, R.W.2    Bosse, M.J.3    Mirza, S.K.4    Lyon, T.R.5    Webb, L.X.6    Pollak, A.N.7    Golden, J.D.8    Valentin-Opran, A.9
  • 40
    • 51649124272 scopus 로고    scopus 로고
    • A comparison of RhBMP-7 (OP-1) and autogenous graft for metaphyseal defects after osteotomy of the distal radius
    • Ekrol I, Hajducka C, Court-Brown C, McQueen MM. A comparison of RhBMP-7 (OP-1) and autogenous graft for metaphyseal defects after osteotomy of the distal radius. Injury 2008, 39(Suppl 2):S73-82.
    • (2008) Injury , vol.39 , Issue.SUPPL. 2
    • Ekrol, I.1    Hajducka, C.2    Court-Brown, C.3    McQueen, M.M.4
  • 42
    • 77950500089 scopus 로고    scopus 로고
    • RhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model
    • 10.2106/JBJS.H.01732, 20124069
    • Seeherman HJ, Li XJ, Bouxsein ML, Wozney JM. rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model. J Bone Joint Surg Am 2010, 92:411-426. 10.2106/JBJS.H.01732, 20124069.
    • (2010) J Bone Joint Surg Am , vol.92 , pp. 411-426
    • Seeherman, H.J.1    Li, X.J.2    Bouxsein, M.L.3    Wozney, J.M.4
  • 43
    • 79959950769 scopus 로고    scopus 로고
    • A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned
    • 10.1016/j.spinee.2011.04.023, 21729796
    • Carragee EJ, Hurwitz EL, Weiner BK. A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned. Spine J 2011, 11:471-491. 10.1016/j.spinee.2011.04.023, 21729796.
    • (2011) Spine J , vol.11 , pp. 471-491
    • Carragee, E.J.1    Hurwitz, E.L.2    Weiner, B.K.3
  • 44
    • 33645508135 scopus 로고    scopus 로고
    • Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion
    • Shields LB, Raque GH, Glassman SD, Campbell M, Vitaz T, Harpring J, Shields CB. Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion. Spine (Phila Pa 1976) 2006, 31:542-547.
    • (2006) Spine (Phila Pa 1976) , vol.31 , pp. 542-547
    • Shields, L.B.1    Raque, G.H.2    Glassman, S.D.3    Campbell, M.4    Vitaz, T.5    Harpring, J.6    Shields, C.B.7
  • 45
    • 35348887265 scopus 로고    scopus 로고
    • Complications of anterior cervical discectomy and fusion using recombinant human bone morphogenetic protein-2
    • 10.1007/s00586-007-0351-9, 2200768, 17387522
    • Vaidya R, Carp J, Sethi A, Bartol S, Craig J, Les CM. Complications of anterior cervical discectomy and fusion using recombinant human bone morphogenetic protein-2. Eur Spine J 2007, 16:1257-1265. 10.1007/s00586-007-0351-9, 2200768, 17387522.
    • (2007) Eur Spine J , vol.16 , pp. 1257-1265
    • Vaidya, R.1    Carp, J.2    Sethi, A.3    Bartol, S.4    Craig, J.5    Les, C.M.6
  • 47
    • 61649100307 scopus 로고    scopus 로고
    • The FGF family: biology, pathophysiology and therapy
    • 10.1038/nrd2792, 19247306
    • Beenken A, Mohammadi M. The FGF family: biology, pathophysiology and therapy. Nat Rev Drug Discov 2009, 8:235-253. 10.1038/nrd2792, 19247306.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 235-253
    • Beenken, A.1    Mohammadi, M.2
  • 48
    • 0141666454 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling controlling osteoblast differentiation
    • Marie PJ. Fibroblast growth factor signaling controlling osteoblast differentiation. Gene 2003, 316:23-32.
    • (2003) Gene , vol.316 , pp. 23-32
    • Marie, P.J.1
  • 49
    • 68049114609 scopus 로고    scopus 로고
    • [Bone fracture and the healing mechanisms. Fibroblast growth factor-2 and fracture healing]
    • In Japanese
    • Kawaguchi H. [Bone fracture and the healing mechanisms. Fibroblast growth factor-2 and fracture healing]. Clin Calcium 2009, 19:653-659. In Japanese.
    • (2009) Clin Calcium , vol.19 , pp. 653-659
    • Kawaguchi, H.1
  • 50
    • 78649581478 scopus 로고    scopus 로고
    • A local application of recombinant human fibroblast growth factor 2 for tibial shaft fractures: a randomized, placebo-controlled trial
    • 10.1002/jbmr.146, 20533373
    • Kawaguchi H, Oka H, Jingushi S, Izumi T, Fukunaga M, Sato K, Matsushita T, Nakamura K. A local application of recombinant human fibroblast growth factor 2 for tibial shaft fractures: a randomized, placebo-controlled trial. J Bone Miner Res 2010, 25:2735-2743. 10.1002/jbmr.146, 20533373.
    • (2010) J Bone Miner Res , vol.25 , pp. 2735-2743
    • Kawaguchi, H.1    Oka, H.2    Jingushi, S.3    Izumi, T.4    Fukunaga, M.5    Sato, K.6    Matsushita, T.7    Nakamura, K.8
  • 51
    • 34047236349 scopus 로고    scopus 로고
    • Local application of recombinant human fibroblast growth factor-2 on bone repair: a dose-escalation prospective trial on patients with osteotomy
    • 10.1002/jor.20315, 17205557
    • Kawaguchi H, Jingushi S, Izumi T, Fukunaga M, Matsushita T, Nakamura T, Mizuno K, Nakamura T, Nakamura K. Local application of recombinant human fibroblast growth factor-2 on bone repair: a dose-escalation prospective trial on patients with osteotomy. J Orthop Res 2007, 25:480-487. 10.1002/jor.20315, 17205557.
    • (2007) J Orthop Res , vol.25 , pp. 480-487
    • Kawaguchi, H.1    Jingushi, S.2    Izumi, T.3    Fukunaga, M.4    Matsushita, T.5    Nakamura, T.6    Mizuno, K.7    Nakamura, T.8    Nakamura, K.9
  • 52
  • 53
    • 44149090296 scopus 로고    scopus 로고
    • Role of platelet-derived growth factors in physiology and medicine
    • 10.1101/gad.1653708, 2732412, 18483217
    • Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev 2008, 22:1276-1312. 10.1101/gad.1653708, 2732412, 18483217.
    • (2008) Genes Dev , vol.22 , pp. 1276-1312
    • Andrae, J.1    Gallini, R.2    Betsholtz, C.3
  • 54
    • 78149388235 scopus 로고    scopus 로고
    • The evolution of rhPDGF-BB in musculoskeletal repair and its role in foot and ankle fusion surgery
    • 10.1016/j.fcl.2010.07.001, 21056861
    • DiGiovanni CW, Petricek JM. The evolution of rhPDGF-BB in musculoskeletal repair and its role in foot and ankle fusion surgery. Foot Ankle Clin 2010, 15:621-640. 10.1016/j.fcl.2010.07.001, 21056861.
    • (2010) Foot Ankle Clin , vol.15 , pp. 621-640
    • DiGiovanni, C.W.1    Petricek, J.M.2
  • 55
    • 77953173253 scopus 로고    scopus 로고
    • Prospective clinical pilot trial in a single cohort group of rhPDGF in foot arthrodeses
    • 10.3113/FAI.2010.0473, 20557811
    • Daniels T, DiGiovanni C, Lau JT, Wing K, Younger A. Prospective clinical pilot trial in a single cohort group of rhPDGF in foot arthrodeses. Foot Ankle Int 2010, 31:473-479. 10.3113/FAI.2010.0473, 20557811.
    • (2010) Foot Ankle Int , vol.31 , pp. 473-479
    • Daniels, T.1    DiGiovanni, C.2    Lau, J.T.3    Wing, K.4    Younger, A.5
  • 56
    • 79954486077 scopus 로고    scopus 로고
    • Prospective, randomized, multi-center feasibility trial of rhPDGF-BB versus autologous bone graft in a foot and ankle fusion model
    • 10.3113/FAI.2011.0344, 21733435
    • Digiovanni CW, Baumhauer J, Lin SS, Berberian WS, Flemister AS, Enna MJ, Evangelista P, Newman J. Prospective, randomized, multi-center feasibility trial of rhPDGF-BB versus autologous bone graft in a foot and ankle fusion model. Foot Ankle Int 2011, 32:344-354. 10.3113/FAI.2011.0344, 21733435.
    • (2011) Foot Ankle Int , vol.32 , pp. 344-354
    • Digiovanni, C.W.1    Baumhauer, J.2    Lin, S.S.3    Berberian, W.S.4    Flemister, A.S.5    Enna, M.J.6    Evangelista, P.7    Newman, J.8
  • 57
    • 34248577022 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
    • 10.1016/j.bone.2007.03.017, 1995599, 17517365
    • Jilka RL. Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone 2007, 40:1434-1446. 10.1016/j.bone.2007.03.017, 1995599, 17517365.
    • (2007) Bone , vol.40 , pp. 1434-1446
    • Jilka, R.L.1
  • 58
    • 77953611907 scopus 로고    scopus 로고
    • Orthopedic uses of teriparatide
    • 10.1007/s11914-010-0006-3, 20425088
    • Bukata SV, Puzas JE. Orthopedic uses of teriparatide. Curr Osteoporos Rep 2010, 8:28-33. 10.1007/s11914-010-0006-3, 20425088.
    • (2010) Curr Osteoporos Rep , vol.8 , pp. 28-33
    • Bukata, S.V.1    Puzas, J.E.2
  • 59
    • 28144446799 scopus 로고    scopus 로고
    • Parathyroid hormone as an anabolic skeletal therapy
    • 10.2165/00003495-200565170-00005, 16296873
    • Rubin MR, Bilezikian JP. Parathyroid hormone as an anabolic skeletal therapy. Drugs 2005, 65:2481-2498. 10.2165/00003495-200565170-00005, 16296873.
    • (2005) Drugs , vol.65 , pp. 2481-2498
    • Rubin, M.R.1    Bilezikian, J.P.2
  • 60
    • 77951210065 scopus 로고    scopus 로고
    • Parathyroid hormone and bone healing
    • 10.1007/s00223-010-9360-5, 20428858
    • Ellegaard M, Jørgensen NR, Schwarz P. Parathyroid hormone and bone healing. Calcif Tissue Int 2010, 87:1-13. 10.1007/s00223-010-9360-5, 20428858.
    • (2010) Calcif Tissue Int , vol.87 , pp. 1-13
    • Ellegaard, M.1    Jørgensen, N.R.2    Schwarz, P.3
  • 61
    • 77950579909 scopus 로고    scopus 로고
    • Teriparatide improves early callus formation in distal radial fractures
    • 10.3109/17453671003761946, 2895344, 20367417
    • Aspenberg P, Johansson T. Teriparatide improves early callus formation in distal radial fractures. Acta Orthop 2010, 81:234-236. 10.3109/17453671003761946, 2895344, 20367417.
    • (2010) Acta Orthop , vol.81 , pp. 234-236
    • Aspenberg, P.1    Johansson, T.2
  • 62
    • 80052871434 scopus 로고    scopus 로고
    • Parathyroid hormone 1-84 accelerates fracture-healing in pubic bones of elderly osteoporotic women
    • 10.2106/JBJS.J.01379, 21915572
    • Peichl P, Holzer LA, Maier R, Holzer G. Parathyroid hormone 1-84 accelerates fracture-healing in pubic bones of elderly osteoporotic women. J Bone Joint Surg Am 2011, 93:1583-1587. 10.2106/JBJS.J.01379, 21915572.
    • (2011) J Bone Joint Surg Am , vol.93 , pp. 1583-1587
    • Peichl, P.1    Holzer, L.A.2    Maier, R.3    Holzer, G.4
  • 64
    • 77954562602 scopus 로고    scopus 로고
    • Successful treatment of sternal fracture nonunion with teriparatide
    • 10.1007/s00198-009-1061-4, 19859645
    • Chintamaneni S, Finzel K, Gruber BL. Successful treatment of sternal fracture nonunion with teriparatide. Osteoporos Int 2010, 21:1059-1063. 10.1007/s00198-009-1061-4, 19859645.
    • (2010) Osteoporos Int , vol.21 , pp. 1059-1063
    • Chintamaneni, S.1    Finzel, K.2    Gruber, B.L.3
  • 65
    • 77951058248 scopus 로고    scopus 로고
    • Teriparatide may accelerate healing in delayed unions of type III odontoid fractures: a report of 3 cases
    • 10.1097/BSD.0b013e31819a8b7a, 20051918
    • Rubery PT, Bukata SV. Teriparatide may accelerate healing in delayed unions of type III odontoid fractures: a report of 3 cases. J Spinal Disord Tech 2010, 23:151-155. 10.1097/BSD.0b013e31819a8b7a, 20051918.
    • (2010) J Spinal Disord Tech , vol.23 , pp. 151-155
    • Rubery, P.T.1    Bukata, S.V.2
  • 66
    • 77956564935 scopus 로고    scopus 로고
    • Atrophic humeral shaft nonunion treated with teriparatide (rh PTH 1-34): a case report
    • Oteo-Alvaro A, Moreno E. Atrophic humeral shaft nonunion treated with teriparatide (rh PTH 1-34): a case report. J Shoulder Elbow Surg 2010, 19:e22-28.
    • (2010) J Shoulder Elbow Surg , vol.19
    • Oteo-Alvaro, A.1    Moreno, E.2
  • 67
    • 0033084785 scopus 로고    scopus 로고
    • Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy
    • 10.1002/(SICI)1521-2254(199903/04)1:2<121::AID-JGM26>3.0.CO;2-J, 10738576
    • Gazit D, Turgeman G, Kelley P, Wang E, Jalenak M, Zilberman Y, Moutsatsos I. Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy. J Gene Med 1999, 1:121-133. 10.1002/(SICI)1521-2254(199903/04)1:2<121::AID-JGM26>3.0.CO;2-J, 10738576.
    • (1999) J Gene Med , vol.1 , pp. 121-133
    • Gazit, D.1    Turgeman, G.2    Kelley, P.3    Wang, E.4    Jalenak, M.5    Zilberman, Y.6    Moutsatsos, I.7
  • 69
    • 79955582337 scopus 로고    scopus 로고
    • 'Same day' ex-vivo regional gene therapy: a novel strategy to enhance bone repair
    • 10.1038/mt.2011.2, 3098640, 21343916
    • Virk MS, Sugiyama O, Park SH, Gambhir SS, Adams DJ, Drissi H, Lieberman JR. 'Same day' ex-vivo regional gene therapy: a novel strategy to enhance bone repair. Mol Ther 2011, 19:960-968. 10.1038/mt.2011.2, 3098640, 21343916.
    • (2011) Mol Ther , vol.19 , pp. 960-968
    • Virk, M.S.1    Sugiyama, O.2    Park, S.H.3    Gambhir, S.S.4    Adams, D.J.5    Drissi, H.6    Lieberman, J.R.7
  • 72
  • 73
    • 79957791010 scopus 로고    scopus 로고
    • Systemic administration of pharmacological agents and bone repair: what can we expect
    • 10.1016/j.injury.2011.03.061, 21507402
    • Bukata SV. Systemic administration of pharmacological agents and bone repair: what can we expect. Injury 2011, 42:605-608. 10.1016/j.injury.2011.03.061, 21507402.
    • (2011) Injury , vol.42 , pp. 605-608
    • Bukata, S.V.1
  • 74
    • 21344450560 scopus 로고    scopus 로고
    • SOST/sclerostin, an osteocyte-derived negative regulator of bone formation
    • 10.1016/j.cytogfr.2005.02.005, 15869900
    • van Bezooijen RL, ten Dijke P, Papapoulos SE, Lowik CW. SOST/sclerostin, an osteocyte-derived negative regulator of bone formation. Cytokine Growth Factor Rev 2005, 16:319-327. 10.1016/j.cytogfr.2005.02.005, 15869900.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 319-327
    • van Bezooijen, R.L.1    ten Dijke, P.2    Papapoulos, S.E.3    Lowik, C.W.4
  • 75
    • 40149102166 scopus 로고    scopus 로고
    • Osteocytederived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling
    • ten Dijke P, Krause C, de Gorter DJ, Lowik CW, van Bezooijen RL. Osteocytederived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling. J Bone Joint Surg Am 2008, 90(Suppl 1):31-35.
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.SUPPL. 1 , pp. 31-35
    • ten Dijke, P.1    Krause, C.2    de Gorter, D.J.3    Lowik, C.W.4    van Bezooijen, R.L.5
  • 78
    • 80755189018 scopus 로고    scopus 로고
    • The emerging role of dickkopf-1 in bone biology: is it the main switch controlling bone and joint remodeling?
    • 10.1016/j.semarthrit.2011.01.006, 21435697
    • Daoussis D, Andonopoulos AP. The emerging role of dickkopf-1 in bone biology: is it the main switch controlling bone and joint remodeling?. Semin Arthritis Rheum 2011, 41:170-177. 10.1016/j.semarthrit.2011.01.006, 21435697.
    • (2011) Semin Arthritis Rheum , vol.41 , pp. 170-177
    • Daoussis, D.1    Andonopoulos, A.P.2
  • 79
    • 79953836062 scopus 로고    scopus 로고
    • The effects of Dickkopf-1 antibody on metaphyseal bone and implant fixation under different loading conditions
    • 10.1016/j.bone.2011.02.008, 21329773
    • Agholme F, Isaksson H, Kuhstoss S, Aspenberg P. The effects of Dickkopf-1 antibody on metaphyseal bone and implant fixation under different loading conditions. Bone 2011, 48:988-996. 10.1016/j.bone.2011.02.008, 21329773.
    • (2011) Bone , vol.48 , pp. 988-996
    • Agholme, F.1    Isaksson, H.2    Kuhstoss, S.3    Aspenberg, P.4
  • 80
    • 79751538912 scopus 로고    scopus 로고
    • Guidelines for fracture healing assessments in clinical trials. Part I: definitions and endpoint committees
    • 10.1016/j.injury.2010.11.048, 21194691
    • Vannabouathong C, Sprague S, Bhandari M. Guidelines for fracture healing assessments in clinical trials. Part I: definitions and endpoint committees. Injury 2011, 42:314-316. 10.1016/j.injury.2010.11.048, 21194691.
    • (2011) Injury , vol.42 , pp. 314-316
    • Vannabouathong, C.1    Sprague, S.2    Bhandari, M.3
  • 81
    • 40149090029 scopus 로고    scopus 로고
    • Clinical trial design in fracture-healing research: meeting the challenge
    • Morshed S, Bhandari M. Clinical trial design in fracture-healing research: meeting the challenge. J Bone Joint Surg Am 2008, 90(Suppl 1):55-61.
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.SUPPL. 1 , pp. 55-61
    • Morshed, S.1    Bhandari, M.2
  • 82
    • 40149090820 scopus 로고    scopus 로고
    • Outcome assessment in clinical trials of fracture-healing
    • Morshed S, Corrales L, Genant H, Miclau T 3. Outcome assessment in clinical trials of fracture-healing. J Bone Joint Surg Am 2008, 90(Suppl 1):62-67.
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.SUPPL. 1 , pp. 62-67
    • Morshed, S.1    Corrales, L.2    Genant, H.3    Miclau T, 3.4
  • 84
    • 85045483986 scopus 로고    scopus 로고
    • Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review
    • iii-iv
    • Garrison KR, Donell S, Ryder J, Shemilt I, Mugford M, Harvey I, Song F. Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review. Health Technol Assess 2007, 11:1-150. iii-iv.
    • (2007) Health Technol Assess , vol.11 , pp. 1-150
    • Garrison, K.R.1    Donell, S.2    Ryder, J.3    Shemilt, I.4    Mugford, M.5    Harvey, I.6    Song, F.7
  • 85
    • 33744815209 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 in open tibial fractures. A subgroup analysis of data combined from two prospective randomized studies
    • 10.2106/JBJS.E.00499, 16757759
    • Swiontkowski MF, Aro HT, Donell S, Esterhai JL, Goulet J, Jones A, Kregor PJ, Nordsletten L, Paiement G, Patel A. Recombinant human bone morphogenetic protein-2 in open tibial fractures. A subgroup analysis of data combined from two prospective randomized studies. J Bone Joint Surg Am 2006, 88:1258-1265. 10.2106/JBJS.E.00499, 16757759.
    • (2006) J Bone Joint Surg Am , vol.88 , pp. 1258-1265
    • Swiontkowski, M.F.1    Aro, H.T.2    Donell, S.3    Esterhai, J.L.4    Goulet, J.5    Jones, A.6    Kregor, P.J.7    Nordsletten, L.8    Paiement, G.9    Patel, A.10
  • 86
    • 57049122787 scopus 로고    scopus 로고
    • Application of rhBMP-7 and platelet-rich plasma in the treatment of long bone non-unions: a prospective randomised clinical study on 120 patients
    • 10.1016/j.injury.2008.08.011, 19027898
    • Calori GM, Tagliabue L, Gala L, d'Imporzano M, Peretti G, Albisetti W. Application of rhBMP-7 and platelet-rich plasma in the treatment of long bone non-unions: a prospective randomised clinical study on 120 patients. Injury 2008, 39:1391-1402. 10.1016/j.injury.2008.08.011, 19027898.
    • (2008) Injury , vol.39 , pp. 1391-1402
    • Calori, G.M.1    Tagliabue, L.2    Gala, L.3    d'Imporzano, M.4    Peretti, G.5    Albisetti, W.6
  • 87
    • 33947229511 scopus 로고    scopus 로고
    • RhBMP-7 accelerates the healing in distal tibial fractures treated by external fixation
    • 10.1302/0301-620X.89B2.18230, 17322450
    • Ristiniemi J, Flinkkila T, Hyvonen P, Lakovaara M, Pakarinen H, Jalovaara P. RhBMP-7 accelerates the healing in distal tibial fractures treated by external fixation. J Bone Joint Surg Br 2007, 89:265-272. 10.1302/0301-620X.89B2.18230, 17322450.
    • (2007) J Bone Joint Surg Br , vol.89 , pp. 265-272
    • Ristiniemi, J.1    Flinkkila, T.2    Hyvonen, P.3    Lakovaara, M.4    Pakarinen, H.5    Jalovaara, P.6
  • 89
    • 36348952295 scopus 로고    scopus 로고
    • The effect of human recombinant bone morphogenic protein (RHBMP-7) on the healing of open tibial shaft fractures: results of a multi-center, prospective, randomized clinical trial
    • Toronto, ON, Canada, the Canadian Orthopaedic Trauma Society St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada (a-Stryker Biotech, Inc.)
    • McKee MD, Schemitsch EH, Waddell JP, Kreder HJ, Stephen DJG, Leighton RK, Buckley RE, Powell JN, Wild LM, Blachut PA, O''Brien PJ, Pirani S, McCormack TG, . the Canadian Orthopaedic Trauma Society St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada (a-Stryker Biotech, Inc.) The effect of human recombinant bone morphogenic protein (RHBMP-7) on the healing of open tibial shaft fractures: results of a multi-center, prospective, randomized clinical trial. Proceedings of the 18th Annual Meeting of the Orthopaedic Trauma Association 2002, 2002:157-158. Toronto, ON, Canada, the Canadian Orthopaedic Trauma Society St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada (a-Stryker Biotech, Inc.).
    • (2002) Proceedings of the 18th Annual Meeting of the Orthopaedic Trauma Association , vol.2002 , pp. 157-158
    • McKee, M.D.1    Schemitsch, E.H.2    Waddell, J.P.3    Kreder, H.J.4    Stephen, D.J.G.5    Leighton, R.K.6    Buckley, R.E.7    Powell, J.N.8    Wild, L.M.9    Blachut, P.A.10    O'Brien, P.J.11    Pirani, S.12    McCormack, T.G.13
  • 90
    • 0032728667 scopus 로고    scopus 로고
    • Osteogenic activity of OP-1 bone morphogenetic protein (BMP-7) in a human fibular defect
    • 10.1302/0301-620X.81B4.9311, 10463751
    • Geesink RG, Hoefnagels NH, Bulstra SK. Osteogenic activity of OP-1 bone morphogenetic protein (BMP-7) in a human fibular defect. J Bone Joint Surg Br 1999, 81:710-718. 10.1302/0301-620X.81B4.9311, 10463751.
    • (1999) J Bone Joint Surg Br , vol.81 , pp. 710-718
    • Geesink, R.G.1    Hoefnagels, N.H.2    Bulstra, S.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.