CXCR6: The Role of Environment in Tumor Progression. Challenges for Therapy

Stem Cell Reviews and Reports

Volumn 8, Issue 4, 2012, Pages 1282-1285

  La Porta, Caterina A M ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Asymmetric self renewal; CXCR6; Microenvironment; Tumor progression

Indexed keywords

ALPHA CHEMOKINE; CCL2 PROTEIN, HUMAN; CHEMOKINE RECEPTOR; CXCL16 PROTEIN, HUMAN; CXCR6 PROTEIN, HUMAN; MONOCYTE CHEMOTACTIC PROTEIN 1; SCAVENGER RECEPTOR; TUMOR PROTEIN; VIRUS RECEPTOR;

ANIMAL; ARTICLE; BIOSYNTHESIS; CANCER INVASION; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; NEOPLASM; PATHOLOGY; PATHOPHYSIOLOGY; TUMOR MICROENVIRONMENT;

ANIMALS; CHEMOKINE CCL2; CHEMOKINES, CXC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOPLASMS; RECEPTORS, CHEMOKINE; RECEPTORS, SCAVENGER; RECEPTORS, VIRUS; TUMOR MICROENVIRONMENT;

ANIMALIA;

EID: 84870386243     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-012-9383-6     Document Type: Article

References (28)

1. Balkwill, F. (2004). Cancer and the chemokine network. Nature Reviews. Cancer, 4(7), 540-555.
2. Houshmond, P., & Zlontik, A. (2003). Therapeutic application in the chemokine superfamily. Current Opinion in Chemical Biology, 7(4), 457-460.
3. Brault, M. S., & Kurt, R. A. (2003). Chemokines and antitumor immunity: walking the tightrope. International Reviews of Immunology, 22(3-4), 199-228.
4. Tsuyada, A., Chow, A., Wu, J. M., Somlo, G., Chu, P., Loera, S., et al. (2012). Fibroblasts that regulates breast cancer stem cells CCL2 mediates crosstalk between cancer cells and stromal. published online first on April 3, doi: 10. 1158/0008-5472. CAN-11-3567.
5. KIn, C. H., Kunkel, E. J., Boisvert, J., Johnson, B., Campbell, J. J., & Genovese, M. C. (2001). Bonzo/CXCR6 expression defines type 1-polarized T cell subsets with with extralymphoid tissue homing potential. The Journal of Clinical Investigation, 107(5), 595-601.
6. Kim, C. H., Johnston, B., & Butcher, E. C. (2002). Traffiking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24 + Vbeta 11 + NKT cel subsets with distinct cytokine-producing capacity. Blood, 100(1), 11-16.
7. Unutmaz, D., Xiang, W., Sunshine, M. J., Campbell, J., Butcher, E., & Littman, D. R. (2000). The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse. Journal of Immunology, 165(6), 3284-3292.
8. Nakayama, T., Hieshima, K., Izawa, D., Tatsumi, Y., Kanamaru, A., Yoshie, O., et al. (2003). Cutting edge: profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues. Journal of Immunology, 170(3), 1136-1140.
9. Matloubian, M., David, A., Engel, S., Ryan, J. E., & Cyster, J. G. (2000). A transmembrane CXC chemokine is a ligand for HIV-coreceptor bonzo. Nature Immunology, 1(4), 298-304.
10. Wilbanks, A., Zondlo, S. C., Murphy, K., Mak, S., Soler, D., Langdon, P., et al. (2001). Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, and CX3C chemokines. Journal of Immunology, 166(8), 5145-5154.
11. Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Kataoka, H., Kita, T., et al. (2000). Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages. Journal of Biological Chemistry, 275(52), 40663-40666.
12. Motsinger, A., Haas, D. W., Stanic, A. K., van Kaer, L., Joyce, S., & Unutmaz, D. (2002). CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection. The Journal of Experimental Medicine, 195(7), 869-879.
13. Zhuge, X., Murayama, T., Arai, H., Yamauchi, R., Tanaka, M., Shimaoka, T., et al. (2005). CXCL16 is a novel angiogenic factor for human umbilical vein endothelial cells. Biochemical and Biophysical Research Communications, 331(4), 1295-1300.
14. van der Voort, R., Verweij, V., de Witte, T. M., Lasonder, E., Adema, G. J., & Dolstra, H. (2010). An alternatively spliced CXCL16 isoform expressed by dendritic cells is a secreted chemoattractant for CXCR6+ cells. Journal of Leukocyte Biology, 87(6), 1029-1039.
15. Matsumura, S., Wang, B., Kawashima, N., Braunstein, S., Badura, M., Cameron, T. O., et al. (2008). Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells. Journal of Immunology, 181(5), 3099-3107.
16. Gaida, M. M., Günther, F., Wagner, C., Friess, H., Giese, N. A., Schmidt, J., et al. (2008). Expression of the CXCR6 on polymorphonuclear neutrophils in pancreatic carcinoma and in acute, localized bacterial infections. Clinical and Experimental Immunology, 154(2), 216-223.
17. Wente, M. N., Gaida, M. M., Mayer, C., Michalski, C. W., Haag, N., Giese, T., et al. (2008). Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. International Journal of Oncology, 33(2), 297-308.
18. Naito, Y., Saito, K., Shiiba, K., Ohuchi, A., Saigenji, K., Nagura, H., et al. (1998). CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Research, 58(16), 3491-3494.
19. Hu, W., Zhen, X., Xiong, B., Wang, B., Zhang, W., & Zhou, W. (2008). CXCR6 is expressed in human prostate cancer in vivo and is involved in the in vitro invasion of PC3 and LNCap cells. Cancer Science, 99(7), 1362-1369.
20. Lu, Y., Wang, J., Xu, Y., Koch, A. E., Cai, Z., Chen, X., et al. (2008). CXCL16 functions as a novel chemotactic factor for prostate cancer cells in vitro. Molecular Cancer Research, 6(4), 546-554.
21. Wang, J., Wang, J., Lu, Y., Wang, J., Koch, A. E., Zhang, J., et al. (2008). CXCR6 induces prostate cancer progression by the AKT/mammalian target of rapamycin signaling pathway. Cancer Research, 68(24), 10367-10376.
22. Seidl, H., Richtig, E., Tilz, H., Stefan, M., Schmidbauer, U., Asslaber, M., et al. (2007). Profiles of chemokine receptors in melanocytic lesions: de novo expression of CXCR6 in melanoma. Human Pathology, 38(5), 768-780.
23. Taghizadeh, R., Noh, M., Huh, Y. H., Ciusani, E., Sigalotti, L., Maio, M., et al. (2010). CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells. PloS One, 5(12), e15183.
24. Deng, I., Chen, N., Li, Y., Zheng, H., & Lei, Q. (2010). CXCR6/CXCL16 functions as a regulator in metastasis and progression of cancer. Biochimica et Biophysica Acta, 1806(1), 42-49.
25. Gutwein, P., Schramme, A., Sinke, N., Abdel-Bakky, M. S., Voss, B., Obermüller, N., et al. (2008). Tumoural CXCL16 expression is a novel prognostic marker of longer survival times in renal cell cancer patients. European Journal of Cancer, 45(3), 478-489.
26. La Porta, C. A. M., Zapperi, S., & Sethna, J. (2012). Senescence cells in growing tumors: population dynamics in cancer stem cells. PLoS Computational Biology, 8, e1002316.
27. Hugo, J., Snippert, L., van der Flier, G., Sato, T., van Es, J. H., van den Born, M., et al. (2010). Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell, 143(1), 134-144.
28. Cicalese, A., Bonizzi, G., Pasi, C. E., Faretta, M., Ronzoni, S., Giulini, B., et al. (2009). The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell, 138(18), 1083-1095.