-
1
-
-
14644435825
-
Intrinsically unstructured proteins and their functions
-
Dyson HJ, Wright PE (2005) Intrinsically unstructured proteins and their functions. Nat Rev Chem Biol 6:197-208.
-
(2005)
Nat Rev Chem Biol
, vol.6
, pp. 197-208
-
-
Dyson, H.J.1
Wright, P.E.2
-
2
-
-
0037188377
-
Intrinsic disorder and protein function
-
Dunker AK, Brown CJ, Lawson JD, Iakoucheva LM, Obradovic Z (2002) Intrinsic disorder and protein function. Biochemistry 41:6573-6582.
-
(2002)
Biochemistry
, vol.41
, pp. 6573-6582
-
-
Dunker, A.K.1
Brown, C.J.2
Lawson, J.D.3
Iakoucheva, L.M.4
Obradovic, Z.5
-
3
-
-
1542358787
-
Prediction and functional analysis of native disorder in proteins from the three kingdoms of life
-
Ward JJ, Sodhi JS, McGuffin LJ, Buxton BF, Jones DT (2004) Prediction and functional analysis of native disorder in proteins from the three kingdoms of life. J Mol Biol 337:635-645.
-
(2004)
J Mol Biol
, vol.337
, pp. 635-645
-
-
Ward, J.J.1
Sodhi, J.S.2
McGuffin, L.J.3
Buxton, B.F.4
Jones, D.T.5
-
4
-
-
79960930163
-
Modeling disordered regions in proteins using Rosetta
-
Wang RY, Han Y, Krassovsky K, Sheffler W, Tyka M, Baker D (2011) Modeling disordered regions in proteins using Rosetta. PloS One 6:e22060.
-
(2011)
PloS One
, vol.6
-
-
Wang, R.Y.1
Han, Y.2
Krassovsky, K.3
Sheffler, W.4
Tyka, M.5
Baker, D.6
-
5
-
-
36749081458
-
Assessment of disorder predictions in CASP7
-
Bordoli L, Kiefer F, Schwede T (2007) Assessment of disorder predictions in CASP7. Proteins 69:129-136.
-
(2007)
Proteins
, vol.69
, pp. 129-136
-
-
Bordoli, L.1
Kiefer, F.2
Schwede, T.3
-
6
-
-
68749093787
-
Predicting intrinsic disorder in proteins: An overview
-
He B, Wang K, Liu Y, Xue B, Uversky VN, Dunker AK (2009) Predicting intrinsic disorder in proteins: an overview. Cell Res 19:929-949.
-
(2009)
Cell Res
, vol.19
, pp. 929-949
-
-
He, B.1
Wang, K.2
Liu, Y.3
Xue, B.4
Uversky, V.N.5
Dunker, A.K.6
-
7
-
-
82655175485
-
A comprehensive overview of computational protein disorder prediction methods
-
Deng X, Eickholt J, Cheng J (2012) A comprehensive overview of computational protein disorder prediction methods. Mol BioSyst 8:114-121.
-
(2012)
Mol BioSyst
, vol.8
, pp. 114-121
-
-
Deng, X.1
Eickholt, J.2
Cheng, J.3
-
8
-
-
79961196239
-
Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE
-
Li X, Wang J, Shi Y (2011) Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE. Nat Commun 2:408.
-
(2011)
Nat Commun
, vol.2
, pp. 408
-
-
Li, X.1
Wang, J.2
Shi, Y.3
-
9
-
-
0031677656
-
Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct
-
Chen GQ, Sun Y, Jin R, Gouaux E (1998) Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct. Protein Sci 7:2623-2630.
-
(1998)
Protein Sci
, vol.7
, pp. 2623-2630
-
-
Chen, G.Q.1
Sun, Y.2
Jin, R.3
Gouaux, E.4
-
10
-
-
0032578635
-
Structure of a glutamate-receptor ligand-binding core in complex with kainate
-
Armstrong N, Sun Y, Chen GQ, Gouaux E (1998) Structure of a glutamate-receptor ligand-binding core in complex with kainate. Nature 395:913-917.
-
(1998)
Nature
, vol.395
, pp. 913-917
-
-
Armstrong, N.1
Sun, Y.2
Chen, G.Q.3
Gouaux, E.4
-
11
-
-
1642514905
-
Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS
-
Pantazatos D, Kim JS, Klock HE, Stevens RC, Wilson IA, Lesley SA, Woods VL Jr (2004) Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS. Proc Natl Acad Sci USA 101:751-756.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 751-756
-
-
Pantazatos, D.1
Kim, J.S.2
Klock, H.E.3
Stevens, R.C.4
Wilson, I.A.5
Lesley, S.A.6
Woods Jr., V.L.7
-
12
-
-
68149164336
-
Construct optimization for protein NMR structure analysis using amide hydrogen/deuterium exchange mass spectrometry
-
Sharma S, Zheng H, Huang YJ, Ertekin A, Hamuro Y, Rossi P, Tejero R, Acton TB, Xiao R, Jiang M, Zhao L, Ma LC, Swapna GV, Aramini JM, Montelione GT (2009) Construct optimization for protein NMR structure analysis using amide hydrogen/deuterium exchange mass spectrometry. Proteins 76:882-894.
-
(2009)
Proteins
, vol.76
, pp. 882-894
-
-
Sharma, S.1
Zheng, H.2
Huang, Y.J.3
Ertekin, A.4
Hamuro, Y.5
Rossi, P.6
Tejero, R.7
Acton, T.B.8
Xiao, R.9
Jiang, M.10
Zhao, L.11
Ma, L.C.12
Swapna, G.V.13
Aramini, J.M.14
Montelione, G.T.15
-
13
-
-
4344707281
-
Unfolded proteins and protein folding studied by NMR
-
Dyson JH, Wright PE (2004) Unfolded proteins and protein folding studied by NMR. Chem Rev 104: 3607-3622.
-
(2004)
Chem Rev
, vol.104
, pp. 3607-3622
-
-
Dyson, J.H.1
Wright, P.E.2
-
14
-
-
79954431523
-
Extension of the HA-detection based approach: (HCA)CON(CA)H and (HCA)NCO(CA)H experiments for the main-chain assignment of intrinsically disordered proteins
-
Mäntylahti S, Hellman M, Permi P (2011) Extension of the HA-detection based approach: (HCA)CON(CA)H and (HCA)NCO(CA)H experiments for the main-chain assignment of intrinsically disordered proteins. J Biomol NMR 49:99-109.
-
(2011)
J Biomol NMR
, vol.49
, pp. 99-109
-
-
Mäntylahti, S.1
Hellman, M.2
Permi, P.3
-
15
-
-
84861304475
-
Recent progress in NMR spectroscopy: Toward the study of intrinsically disordered proteins of increasing size and complexity
-
Felli IC, Pierattelli R (2012) Recent progress in NMR spectroscopy: toward the study of intrinsically disordered proteins of increasing size and complexity. IUBMB Life 64:473-481.
-
(2012)
IUBMB Life
, vol.64
, pp. 473-481
-
-
Felli, I.C.1
Pierattelli, R.2
-
16
-
-
33645452144
-
Protonless NMR experiments for sequence-specific backbone nuclei in unfolded proteins
-
Bermel W, Bertini I, Felli IC, Lee YM, Luchinat C, Pierattelli R (2006) Protonless NMR experiments for sequence-specific backbone nuclei in unfolded proteins. J Am Chem Soc 128:3918-3919.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 3918-3919
-
-
Bermel, W.1
Bertini, I.2
Felli, I.C.3
Lee, Y.M.4
Luchinat, C.5
Pierattelli, R.6
-
17
-
-
67650564478
-
Use of protonless NMR spectroscopy to alleviate the loss of information resulting from exchange-broadening
-
Hsu ST, Bertoncini CW, Dobson CM (2009) Use of protonless NMR spectroscopy to alleviate the loss of information resulting from exchange-broadening. J Am Chem Soc 131:7222-7223.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 7222-7223
-
-
Hsu, S.T.1
Bertoncini, C.W.2
Dobson, C.M.3
-
18
-
-
67749121986
-
Structural characterization of the natively unfolded N-terminal domain of human c-Src kinase: Insights into the role of phosphorylation of the unique domain
-
Pérez Y, Gairí M, Pons M, Bernadó P (2009) Structural characterization of the natively unfolded N-terminal domain of human c-Src kinase: insights into the role of phosphorylation of the unique domain. J Mol Biol 391: 136-148.
-
(2009)
J Mol Biol
, vol.391
, pp. 136-148
-
-
Pérez, Y.1
Gairí, M.2
Pons, M.3
Bernadó, P.4
-
19
-
-
77955806625
-
Molten globule precursor states are conformationally correlated to amyloid fibrils of human beta-2-microglobulin
-
Skora L, Becker S, Zweckstetter M (2010) Molten globule precursor states are conformationally correlated to amyloid fibrils of human beta-2- microglobulin. J Am Chem Soc 132:9223-9225.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 9223-9225
-
-
Skora, L.1
Becker, S.2
Zweckstetter, M.3
-
20
-
-
78650333131
-
Molecular basis of the mixed lineage leukemia-menin interaction: Implications for targeting mixed lineage leukemias
-
Grembecka J, Belcher AM, Hartley T, Cierpicki T (2010) Molecular basis of the mixed lineage leukemia-menin interaction: implications for targeting mixed lineage leukemias. J Biol Chem 285:40690-40698.
-
(2010)
J Biol Chem
, vol.285
, pp. 40690-40698
-
-
Grembecka, J.1
Belcher, A.M.2
Hartley, T.3
Cierpicki, T.4
-
21
-
-
0030963446
-
Positional cloning of the gene for multiple endocrine neoplasia-type 1
-
Chandrasekharappa SC, Guru SC, Manickam P, Olufemi SE, Collins FS, Emmert-Buck MR, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Crabtree JS, Wang Y, Roe BA, Weisemann J, Boguski MS, Agarwal SK, Kester MB, Kim YS, Heppner C, Dong Q, Spiegel AM, Burns AL, Marx SJ (1997) Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science 276:404-407.
-
(1997)
Science
, vol.276
, pp. 404-407
-
-
Chandrasekharappa, S.C.1
Guru, S.C.2
Manickam, P.3
Olufemi, S.E.4
Collins, F.S.5
Emmert-Buck, M.R.6
Debelenko, L.V.7
Zhuang, Z.8
Lubensky, I.A.9
Liotta, L.A.10
Crabtree, J.S.11
Wang, Y.12
Roe, B.A.13
Weisemann, J.14
Boguski, M.S.15
Agarwal, S.K.16
Kester, M.B.17
Kim, Y.S.18
Heppner, C.19
Dong, Q.20
Spiegel, A.M.21
Burns, A.L.22
Marx, S.J.23
more..
-
22
-
-
26844555530
-
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis
-
Yokoyama A, Somervaille TC, Smith KS, Rozenblatt-Rosen O, Meyerson M, Cleary ML (2005) The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis. Cell 123:207-218.
-
(2005)
Cell
, vol.123
, pp. 207-218
-
-
Yokoyama, A.1
Somervaille, T.C.2
Smith, K.S.3
Rozenblatt-Rosen, O.4
Meyerson, M.5
Cleary, M.L.6
-
23
-
-
80052417111
-
Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) protein
-
Murai MJ, Chruszcz M, Reddy G, Grembecka J, Cierpicki T (2011) Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) protein. J Biol Chem 286:31742-31748.
-
(2011)
J Biol Chem
, vol.286
, pp. 31742-31748
-
-
Murai, M.J.1
Chruszcz, M.2
Reddy, G.3
Grembecka, J.4
Cierpicki, T.5
-
24
-
-
84862777931
-
The same pocket in menin binds both MLL and JunD but has opposite effect on transcription
-
Huang J, Gurung B, Wan B, Matkar S, Veniaminova NA, Wan K, Merchant JL, Hua X, Lei M (2012) The same pocket in menin binds both MLL and JunD but has opposite effect on transcription. Nature 482:542-546.
-
(2012)
Nature
, vol.482
, pp. 542-546
-
-
Huang, J.1
Gurung, B.2
Wan, B.3
Matkar, S.4
Veniaminova, N.A.5
Wan, K.6
Merchant, J.L.7
Hua, X.8
Lei, M.9
-
25
-
-
18844420024
-
Complete assignment of heteronuclear protein resonances by protonless NMR spectroscopy
-
Bermel W, Bertini I, Duma L, Felli IC, Emsley L, Pierattelli R, Vasos PR (2005) Complete assignment of heteronuclear protein resonances by protonless NMR spectroscopy. Angew Chem Int Ed Engl 44:3089-3092.
-
(2005)
Angew Chem Int Ed Engl
, vol.44
, pp. 3089-3092
-
-
Bermel, W.1
Bertini, I.2
Duma, L.3
Felli, I.C.4
Emsley, L.5
Pierattelli, R.6
Vasos, P.R.7
-
26
-
-
11344281375
-
A selective experiment for the sequential protein backbone assignment from 3D heteronuclear spectra
-
Bermel W, Bertini I, Felli IC, Pierattelli R, Vasos PR (2005) A selective experiment for the sequential protein backbone assignment from 3D heteronuclear spectra. J Mag Res 172:324-328.
-
(2005)
J Mag Res
, vol.172
, pp. 324-328
-
-
Bermel, W.1
Bertini, I.2
Felli, I.C.3
Pierattelli, R.4
Vasos, P.R.5
-
27
-
-
78650615363
-
Sequence-specific random coil chemical shifts of intrinsically disordered proteins
-
Tamiola K, Acar B, Mulder FA (2010) Sequence-specific random coil chemical shifts of intrinsically disordered proteins. J Am Chem Soc 132:18000-18003.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 18000-18003
-
-
Tamiola, K.1
Acar, B.2
Mulder, F.A.3
-
28
-
-
0034836367
-
Sequence-dependent correction of random coil NMR chemical shifts
-
Schwarzinger S, Kroon GJ, Foss TR, Chung J, Wright PE, Dyson HJ (2001) Sequence-dependent correction of random coil NMR chemical shifts. J Am Chem Soc 123:2970-2978.
-
(2001)
J Am Chem Soc
, vol.123
, pp. 2970-2978
-
-
Schwarzinger, S.1
Kroon, G.J.2
Foss, T.R.3
Chung, J.4
Wright, P.E.5
Dyson, H.J.6
-
29
-
-
0036129107
-
Probability-based protein secondary structure identification using combined NMR chemical-shift data
-
Wang Y, Jardetzky O (2002) Probability-based protein secondary structure identification using combined NMR chemical-shift data. Protein Sci 11:852-861.
-
(2002)
Protein Sci
, vol.11
, pp. 852-861
-
-
Wang, Y.1
Jardetzky, O.2
-
30
-
-
84871353492
-
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia
-
(in press) e-pub: blood-2012-05-429274v1
-
Shi A, Murai MJ, He S, Lund G, Hartley T, Purohit T, Reedy G, Chruszcz M, Grembecka J, Cierpicki T (in press) Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia. Blood; e-pub: blood-2012-05-429274v1.
-
Blood
-
-
Shi, A.1
Murai, M.J.2
He, S.3
Lund, G.4
Hartley, T.5
Purohit, T.6
Reedy, G.7
Chruszcz, M.8
Grembecka, J.9
Cierpicki, T.10
-
31
-
-
9344256689
-
On the use of DXMS to produce more crystallizable proteins: Structures of the T. maritima proteins TM0160 and TM1171
-
Spraggon G, Pantazatos D, Klock HE, Wilson IA, Woods VL Jr, Lesley SA (2004) On the use of DXMS to produce more crystallizable proteins: structures of the T. maritima proteins TM0160 and TM1171. Protein Sci 13:3187-3199.
-
(2004)
Protein Sci
, vol.13
, pp. 3187-3199
-
-
Spraggon, G.1
Pantazatos, D.2
Klock, H.E.3
Wilson, I.A.4
Woods Jr., V.L.5
Lesley, S.A.6
-
32
-
-
0029400480
-
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
-
Delaglio F, Grzesiek S, Vuister GW, Zhu G, Pfeifer J, Bax A (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR 6:277-293.
-
(1995)
J Biomol NMR
, vol.6
, pp. 277-293
-
-
Delaglio, F.1
Grzesiek, S.2
Vuister, G.W.3
Zhu, G.4
Pfeifer, J.5
Bax, A.6
|