Antiproliferative potency of novel benzofuran-2-carboxamides on tumour cell lines: Cell death mechanisms and determination of crystal structure

European Journal of Medicinal Chemistry

Volumn 59, Issue , 2013, Pages 111-119

  Hranjec, Marijana ^a   Sović, Irena ^a   Ratkaj, Ivana ^b   Pavlović, Gordana ^c   Ilić, Nataša ^b   Valjalo, Linda ^a   Pavelić, Krešimir ^b   Kraljević Pavelić, Sandra ^b   Karminski Zamola, Grace ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b University of Rijeka   (Croatia)

^c UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Antiproliferative activity; Apoptosis; Benzofuranes; Carboxamides; Crystal structure determination

Indexed keywords

AMIDE; BENZOFURAN DERIVATIVE; N (2 ACETAMIDOPYRIDIN 3 YL)BENZOFURAN 2 CARBOXAMIDE; N (4 ACETAMIDOPHENYL)BENZOFURAN 2 CARBOXAMIDE; N (4 CYANOPHENYL)BENZOFURAN 2 CARBOXAMIDE; N (4 N,N DIMETHYLAMINOPHENYL)BENZOFURAN 2 CARBOXAMIDE; N (4 N,N DIMETHYLAMINOPHENYL)BENZOFURAN 2 CARBOXAMIDE HYDROCHLORIDE; N (4 NITROPHENYL)BENZOFURAN 2 CARBOXAMIDE; N (5 CYANOPYRIDIN 2 YL)BENZOFURAN 2 CARBOXAMIDE; N (5 NITROPYRIDIN 2 YL)BENZOFURAN 2 CARBOXAMIDE; N (6 CYANOBENZIMIDAZOL 2 YL)BENZOFURAN 2 CARBOXAMIDE; N (6 CYANOBENZOTHIAZOL 2 YL)BENZOFURAN 2 CARBOXAMIDE; N (6 NITROBENZIMIDAZOL 2 YL)BENZOFURAN 2 CARBOXAMIDE; N (6 NITROBENZOTHIAZOL 2 YL)BENZOFURAN 2 CARBOXAMIDE; N [4 (2 IMIDAZOLYNYL)PHENYL]BENZOFURAN 2 CARBOXAMIDE HYDROCHLORIDE; N [5 (2 IMIDAZOLYNYL)PYRIDIN 2 YL]BENZOFURAN 2 CARBOXAMIDE HYDROCHLORIDE; N [6 (2 IMIDAZOLYNYL)BENIMIDAZOL 2 YL]BENZOFURAN 2 CARBOXAMIDE HYDROCHLORIDE; N [6 (2 IMIDAZOLYNYL)BENZOTHIAZOL 2 YL]BENZOFURAN 2 CARBOXAMIDE HYDROCHLORIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE; CELL STRUCTURE; CONCENTRATION RESPONSE; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ANALYSIS; TUMOR CELL;

AMIDES; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOFURANS; CARBOXYLIC ACIDS; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; FLOW CYTOMETRY; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MOLECULAR STRUCTURE;

EID: 84870347086     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.11.009     Document Type: Article

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