Single-walled carbon nanotubes promote rat vascular adventitial fibroblasts to transform into myofibroblasts by SM22-α expression

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 4199-4206

  Lin, Zhiqing ^a   Liu, Lihua ^a   Xi, Zhuge ^a   Huang, Jiehua ^a   Lin, Bencheng ^a  

^a INSTITUTE OF HEALTH AND ENVIRONMENTAL MEDICINE   (China)

Author keywords

Signal pathway; SM22 ; SWCNTs; Tissue engineering materials; VAFs

Indexed keywords

MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SINGLE WALLED NANOTUBE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; TRANSGELIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL ENGINEERING; CELL TRANSFORMATION; CELL ULTRASTRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DNA CROSS LINKING; FIBROBLAST; GENE EXPRESSION REGULATION; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; MYOFIBROBLAST; NONHUMAN; OXIDATIVE STRESS; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; RAT; TISSUE ENGINEERING; TRANSMISSION ELECTRON MICROSCOPY; VASCULAR ADVENTITIAL FIBROBLAST; WESTERN BLOTTING;

ADVENTITIA; ANIMALS; CELL DIFFERENTIATION; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; FIBROBLASTS; MAP KINASE SIGNALING SYSTEM; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; MYOFIBROBLASTS; NANOTUBES, CARBON; OXIDATIVE STRESS; RATS; TISSUE ENGINEERING;

RATTUS;

EID: 84870332564     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S34663     Document Type: Article

References (23)

1. Wu Y, Phillips JA, Liu H, Yang R, Tan W. Carbon nanotubes protect DNA strands during cellular delivery. ACS Nano. 2008;2(10):2023-2028.
2. Zhang X, Meng L, Lu Q, Fei Z, Dyson PJ. Targeted delivery and controlled release of doxorubicin to cancer cells using modified single wall carbon nanotubes. Biomaterials. 2009;30(30):6041-6047.
3. Bussy C, Cambedouzou J, Lanone S, etal. Carbon nanotubes in macrophages: imaging and chemical analysis by X-ray fluorescence microscopy. Nano Lett. 2008;8(9):2659-2663.
4. Choudhary S, Quin MB, Sanders MA, Johnson ET, Schmidt-Dannert C. Engineered protein nano-compartments for targeted enzyme localization. PLoS One. 2012;7(3):e33342.
5. Miller DC, Thapa A, Haberstroh KM, Webster TJ. Endothelial and vascular smooth muscle cell function on poly(lactic-co-glycolic acid) with nano-structured surface features. Biomaterials. 2004;25(1):53-61.
6. Miller DC, Haberstroh KM, Webster TJ. Mechanism(s) of increased vascular cell adhesion on nanostructured poly(lactic-co-glycolic acid) films. J Biomed Mater Res A. 2005;73(4):476-484.
7. Miller DC, Haberstroh KM, Webster TJ. PLGA nanometer surface features manipulate fibronectin interactions for improved vascular cell adhesion. J Biomed Mater Res A. 2007;81(3):678-684.
8. Lee SJ, Yoo JJ, Lim GJ, Atala A, Stitzel J. In vitro evaluation of electrospun nanofiber scaffolds for vascular graft application. J Biomed Mater Res A. 2007;83(4):999-1008.
9. Xu CY, Inai R, Kotaki M, Ramakrishna S. Aligned biodegradable nanofibrous structure: a potential scaffold for blood vessel engineering. Biomaterials. 2004;25(5):877-886.
10. Genové E, Shen C, Zhang S, Semino CE. The effect of functionalized self-assembling peptide scaffolds on human aortic endothelial cell function. Biomaterials. 2005;26(16):3341-3345.
11. Ehrlich H, Koutsoukos PG, Demadis KD, Pokrovsky OS. Principles of demineralization: modern strategies for the isolation of organic frameworks. Part I. Common definitions and history. Micron. 2008; 39(8):1062-1091.
12. Harrington DA, Cheng EY, Guler MO, etal. Branched peptide-amphiphiles as self-assembling coatings for tissue engineering scaffolds. J Biomed Mater Res A. 2006;78(1):157-167.
13. KB signaling, and promoting fibroblast-to-myofibroblast transformation. Chem Res Toxicol. 2011;24(12):2237-2248.
14. Zhang Y, Mu Q, Zhou H, etal. Binding of carbon nanotube to BMP receptor 2 enhances cell differentiation and inhibits apoptosis via regulating bHLH transcription factors. Cell Death Dis. 2012;3:e308.
15. Herzog E, Byrne HJ, Davoren M, Casey A, Duschl A, Oostingh GJ. Dispersion medium modulates oxidative stress response of human lung epithelial cells upon exposure to carbon nanomaterial samples. Toxicol Appl Pharmacol. 2009;236(3):276-281.
16. Liu Y, Li CM, Lu Z, Ding S, Yang X, Mo J. Studies on formation and repair of formaldehyde-damaged DNA by detection of DNA-protein crosslinks and DNA breaks. Front Biosci. 2006;11:991-997.
17. Hsin YH, Chen CF, Huang S, Shih TS, Lai PS, Chueh PJ. The apoptotic effect of nanosilver is mediated by a ROS-and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3cells. Toxicology Lett. 2008;179(3):130-139.
18. Yang Z, Zhang Y, Yang Y, etal. Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating Alzheimer disease. Nanomedicine. 2010;6(3):427-441.
19. Wick P, Manser P, Limbach LK, etal. The degree and kind of agglomeration affect carbon nanotube cytotoxicity. Toxicology Lett. 2007;168(2):121-131.
20. Lu W, Tan YZ, Hu KL, Jiang XG. Cationic albumin conjugated pegylated nanoparticle with its transcytosis ability and little toxicity against blood-brain barrier. Int J Pharm. 2005;295(1-2):247-260.
21. Tin-Tin-Win-Shwe, Yamamoto S, Ahmed S, etal. Brain cytokine and chemokine mRNA expression in mice induced by intranasal instillation with ultrafine carbon black. Toxicology Lett. 2006;163(2):153-160.
22. Rotoli BM, Bussolati O, Bianchi MG, etal. Non-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cells. Toxicology Lett. 2008;178(2):95-102.
23. Alazzam A, Mfoumou E, Stiharu I, etal. Identification of deregulated genes by single wall carbon-nanotubes in human normal bronchial epithelial cells. Nanomedicine. 2010;6(4):563-569.