Progesterone Acts via the Nuclear Glucocorticoid Receptor to Suppress IL-1β-Induced COX-2 Expression in Human Term Myometrial Cells

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Lei, Kaiyu ^a,b   Chen, Li ^a,c   Georgiou, Ektoras X ^a   Sooranna, Suren R ^a,b   Khanjani, Shirin ^b   Brosens, Jan J ^b   Bennett, Phillip R ^b   Johnson, Mark R ^a,b  

^a CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

^b Institute of Reproductive and Developmental Biology   (United Kingdom)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA [4 (DIMETHYLAMINO)PHENYL] 4',5' DIHYDRO 6BETA METHYLSPIRO[ESTRA 4,9 DIENE 17BETA,2'(3'H) FURAN] 3 ONE; CYCLOOXYGENASE 2; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MIFEPRISTONE; PROGESTERONE; PROGESTERONE RECEPTOR B; SMALL INTERFERING RNA; SYNAPTOTAGMIN I;

ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; FKBP5 GENE; GENE ACTIVATION; GENE CONSTRUCT; GENE EXPRESSION; GENE OVEREXPRESSION; HORMONE ACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MONOTHERAPY; MYOMETRIUM; NUCLEOTIDE SEQUENCE; P65 GENE; PRE GENE; PROTEIN EXPRESSION; REPORTER GENE; SMOOTH MUSCLE FIBER;

CELL NUCLEUS; CELLS, CULTURED; CYCLOOXYGENASE 2; ESTRENES; FEMALE; FURANS; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE SILENCING; GENES, REPORTER; HUMANS; INTERLEUKIN-1BETA; MIFEPRISTONE; MYOMETRIUM; NF-KAPPA B; PROGESTERONE; RECEPTORS, GLUCOCORTICOID; RECEPTORS, PROGESTERONE; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR RELA;

EID: 84870327686     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050167     Document Type: Article

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