Cellular interaction of folic acid conjugated superparamagnetic iron oxide nanoparticles and its use as contrast agent for targeted magnetic imaging of tumor cells

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 3503-3516

  Kumar, Manoj ^a   Singh, Gurpal ^a   Arora, Vikas ^a   Mewar, Sujeet ^b   Sharma, Uma ^b   Jagannathan, N R ^b   Sapra, Sameer ^a   Dinda, Amit K ^b   Kharbanda, Surender ^c   Singh, Harpal ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cancer cell targeting ligand; Cellular internalization; Magnetic resonance imaging (MRI); Superparamagnetic iron oxide nanoparticles (SPION)

Indexed keywords

2 BROMO 2 METHYLPROPIONIC ACID; CITRIC ACID; CONTRAST MEDIUM; FOLATE RECEPTOR; FOLIC ACID; IRON; ISOBUTYRIC ACID DERIVATIVE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; BREAST CARCINOMA; CELL INTERACTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; DRUG COATING; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG EFFICACY; DRUG MECHANISM; DRUG SYNTHESIS; DRUG UPTAKE; ENDOCYTOSIS; HYDROPHILICITY; IN VITRO STUDY; INTERNALIZATION; LIGAND BINDING; LIVER CELL CARCINOMA; NANOMEDICINE; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; SENSITIVITY AND SPECIFICITY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE; ULTRASTRUCTURE;

CONTRAST MEDIA; DRUG STABILITY; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; HEP G2 CELLS; HISTOCYTOCHEMISTRY; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MAGNETIC RESONANCE SPECTROSCOPY; MAGNETITE NANOPARTICLES; MCF-7 CELLS; MICROSCOPY, ELECTRON, TRANSMISSION; PHANTOMS, IMAGING;

EID: 84870314992     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S32694     Document Type: Article

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