Cuprous oxide nanoparticles selectively induce apoptosis of tumor cells

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 2641-2652

  Wang, Ye ^a   Zi, Xiao Yuan ^a   Su, Juan ^a   Zhang, Hong Xia ^a   Zhang, Xin Rong ^a   Zhu, Hai Ying ^a   Li, Jian Xiu ^a   Yin, Meng ^a   Yang, Feng ^a   Hu, Yi Ping ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle arrest; Mitochondriontargeted nanomaterials; Nanomedicine; Selective cytotoxicity

Indexed keywords

CUPROUS OXIDE NANOPARTICLE; NANOPARTICLE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL MOTION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; EMBRYO CELL; FIBROBLAST; G1 PHASE CELL CYCLE CHECKPOINT; HELA CELL; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MELANOMA CELL; MEMBRANE DAMAGE; MITOCHONDRION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL;

ANIMALS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COPPER; DITHIOTHREITOL; FIBROBLASTS; FLOW CYTOMETRY; HELA CELLS; HUMANS; LIPID PEROXIDATION; METAL NANOPARTICLES; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; TOXICITY TESTS;

EID: 84870308185     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S31133     Document Type: Article

References (40)

1. Service RF. Nanotechnology grows up. Science. 2004;18:1732-1734.
2. Sahoo SK, Parveen S, Panda JJ. The present and future of nanotechnology in human health care. Nanomedicine. 2007;3:20-31.
3. Twan L, Vladimir S, Karel U, et al. Polymeric nanomedicines for imageguided drug delivery and tumor-targeted combination therapy. Nano Today. 2010;5:197-212.
4. Yang F, Tang Q, Zhong X, et al. Surface decoration by Spirulina polysaccharide enhances the cellular uptake and anticancer efficacy of selenium nanoparticles. Int J Nanomedicine. 2012;7:835-844.
5. Lee P, Zhang R, Li V, et al. Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation. Int J Nanomedicine. 2012;7:731-737.
6. Murphy EA, Majeti BK, Barnes LA, et al. Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis. Proc Natl Acad Sci U S A. 2008;105:9343-9348.
7. Siddiqui IA, Adhami VM, Christopher J, Chamcheu, Mukhtar H. Impact of nanotechnology in cancer: emphasis on nanochemoprevention. Int J Nanomedicine. 2012;7:591-605.
8. Stevens MM, Ghadiali JE, Cohen BE. Protein kinase-actuated resonance energy transfer in quantum dot-peptide conjugates. ACS Nano. 2010;4: 4915-4919.
9. Durmus NG, Taylor EN, Inci F, et al. Fructose-enhanced reduction of bacterial growth on nanorough surfaces. Int J Nanomedicine. 2012;7:537-545.
10. Shen S, Chow PS, Chen F, Tan RB. Submicron particles of SBA-15 modified with MgO as carriers for controlled drug delivery. Chem Pharm Bull. 2007;55:985-991.
11. Seo WS, Lee JH, Sun X, et al. FeCo/graphitic-shell nanocrystals as advanced magnetic-resonance-imaging and near-infrared agents. Nat Mater. 2006;5:971-976.
12. Visaria RK, Griffin RJ, Williams BW, et al. Enhancement of tumor thermal therapy using gold nanoparticle-assisted tumor necrosis factor-A delivery. Mol Cancer Ther. 2006;5:1014-1020.
13. Cartwright L, Poulsen MS, Nielsen HM, et al. In vitro placental model optimization for nanoparticle transport studies. Int J Nanomedicine. 2012;7:497-510.
14. Neeshma D, Juewen L. Programmable assembly of DNA-functionalized liposomes by DNA. ACS Nano. 2011;5:1304-1312.
15. Mariappan P, Krishnamoorthy K, Kadarkaraithangam J, Govindasamy M. Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation. Nanomedicine. 2011;7:184-192.
16. Wu YN, Chen DH, Shi XY, et al. Cancer-cell-specific cytotoxicity of non-oxidized iron elements in iron core-gold shell NPs. Nanomedicine. 2011;7:420-427.
17. Becker AL, Orlotti NI, Folini M, et al. Redox-active polymer microcapsules for the delivery of a survivin-specific siRNA in prostate cancer cells. ACS Nano. 2011;5:1335-1344.
18. Xia T, Zhao Y, Sager T, et al. Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. ACS Nano. 2011;5:1223-1235.
19. 3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proc Natl Acad Sci U S A. 2004;101:5328-5335.
20. Chen Z, Wang ZY, Chen SJ. Acute promyelocytic leukemia: cellular and molecular basis of differentiation and apoptosis. Pharmacol Ther. 1997;76:141-149.
21. Wang ZY, Chen Z. Differentiation and apoptosis induction therapy in acute promyelocytic leukemia. Lancet Oncol. 2000;1:101-106.
22. Qi WJ, Huang CZ, Chen LQ. Cuprous oxide nanospheres as probes for light scattering imaging analysis of live cells and for conformation identification of proteins. Talanta. 2010;80:1400-1405.
23. Liu P, Yang S, Fang M, Luo X, Cai W. Complex nanostructures synthesized from nanoparticle colloids under an external electric field. Nanoscale. 2011;1:3933-3940.
24. 4 solution layer. J Electroanal Chem. 2010;638:225-230.
25. 2O nanowires: growth morphology, spectroscopic and electrical characterization. Nanotechnology. 2012;23:075601.
26. Yan XY, Tong XL, Zhang YF, et al. Cuprous oxide nanoparticles dispersed on reduced graphene oxide as an efficient electrocatalyst for oxygen reduction reaction. Chem Commun Camb. 2012;48:1892-1894.
27. Chi Y, Zhou S, Wan F. Flow cytometric analysis of the anticancer effects of copper acetate. Journal of China-Japan Friendship Hospital. 1994;8:63-66.
28. Daniel CJ, Casey CR, Miles FB, David NM, Rodney A. In vitro proliferating cell models to study cytotoxicity of silica nanowires. Nanomedicine. 2010;6:84-92.
29. Hajra KM, Liu JR. Apoptosome dysfunction in human cancer. Apoptosis. 2004;6:691-704.
30. Szeto HH. Cell-permeable, mitochondrial-targeted, peptide antioxidants. AAPS J. 2006;2:E277-E283.
31. AshaRani PV, Low KMG, Hande MP, Valiyaveettil S. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano. 2009;3:279-290.
32. Kumar R, Dwivedi PD, Dhawan A, Das M, Ansari KM. Citrinin-generated reactive oxygen species cause cell cycle arrest leading to apoptosis via the intrinsic mitochondrial pathway in mouse skin. Toxicol Sci. 2011;2:557-566.
33. Wang LM, Liu Y, Li W, Jiang XM, Chen CY. Selective targeting of gold nanorods at the mitochondria of cancer cells: implications for cancer therapy. Nano Lett. 2011;2:772-780.
34. Misawa M, Takahashi J. Generation of reactive oxygen species induced by gold nanoparticles under x-ray and UV irradiations. Nanomedicine. 2011;7:604-614.
35. Sauvain JJ, Riediker M, Deslarzes S. Nanoparticle reactivity toward dithiothreitol. Nanotoxicology. 2008;2:121-129.
36. Xia T, Kovochich M, Brant J, et al. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett. 2006;1:1794-1807.
37. 2O nanocubes. Mater Lett. 2009;63:400-402.
38. Yong HH, Sung ZK, Suhn HK, Woo HP. Apoptosis in pyrogallol-treated Calu-6 cells is correlated with the changes of intracellular GSH levels rather than ROS levels. Lung Cancer. 2008;59:301-314.
39. Wu M, Huang J, Xu S, Ling T, Xie Y, Shen W. Reactive oxygen species (ROS) are essential mediators in epidermal growth factor (EGF)-stimulated corneal epithelial cell proliferation, adhesion, migration, and wound healing. Exp Eye Res. 2009;89:876-886.
40. 2O nanocrystals and their properties. Nano Today. 2010;5:106-116.