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Volumn 164, Issue 6, 2012, Pages

Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C5A; COMPLEMENT MEMBRANE ATTACK COMPLEX; PEXELIZUMAB;

EID: 84870299885     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2012.09.012     Document Type: Letter
Times cited : (4)

References (8)
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    • C. Martel, C.B. Granger, and M. Ghitescu Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial Am Heart J 164 2012 43 51
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  • 2
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    • Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation
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    • (1995) J Clin Invest , vol.96 , pp. 1564-1572
    • Rinder, C.S.1    Rinder, H.M.2    Smith, B.R.3
  • 3
    • 0033613528 scopus 로고    scopus 로고
    • Pharmacology and biological efficacy of a recombinant, humanized, single-chain antibody C5 complement inhibitor in patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass
    • J.C. Fitch, S. Rollins, and L. Matis Pharmacology and biological efficacy of a recombinant, humanized, single-chain antibody C5 complement inhibitor in patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass Circulation 100 1999 2499 2506
    • (1999) Circulation , vol.100 , pp. 2499-2506
    • Fitch, J.C.1    Rollins, S.2    Matis, L.3
  • 4
    • 0029029540 scopus 로고
    • The fluid-phase SC5b-9 terminal complement complex binds to the GPIIb/IIIa complex of thrombin-stimulated human blood platelets inhibiting platelet aggregation
    • M. Roger, K. Hogåsen, and P.A. Holme The fluid-phase SC5b-9 terminal complement complex binds to the GPIIb/IIIa complex of thrombin-stimulated human blood platelets inhibiting platelet aggregation Platelet 6 1995 160 168
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    • Roger, M.1    Hogåsen, K.2    Holme, P.A.3
  • 5
    • 78651422977 scopus 로고    scopus 로고
    • Pexelizumab may be hazardous to those with ST-segment elevation myocardial infarction undergoing primary percutaneous interventions without using glycoprotein IIb-IIIa inhibitors
    • G.M. Lin, K.M. Chu, and C.L. Han Pexelizumab may be hazardous to those with ST-segment elevation myocardial infarction undergoing primary percutaneous interventions without using glycoprotein IIb-IIIa inhibitors Int J Cardiol 146 2010 280 282
    • (2010) Int J Cardiol , vol.146 , pp. 280-282
    • Lin, G.M.1    Chu, K.M.2    Han, C.L.3
  • 6
    • 79951953841 scopus 로고    scopus 로고
    • Predictors, moderators and mediators for the effectiveness of pexelizumab treatment in patients undergoing primary coronary revascularization
    • G.M. Lin, Y.H. Li, and S.H. Wen Predictors, moderators and mediators for the effectiveness of pexelizumab treatment in patients undergoing primary coronary revascularization Int J Cardiol 147 2011 340 341
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  • 7
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    • G.M. Lin Pexelizumab, an anti-C5 complement antibody for primary coronary revascularization: a new insight from old versions Cardiovasc Hematol Disord Drug Targets 11 2011 97 101
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    • Lin, G.M.1
  • 8
    • 0031692829 scopus 로고    scopus 로고
    • Interleukin-6 derived from hypoxic myocytes promotes neutrophil-mediated reperfusion injury in myocardium
    • Y. Sawa, H. Ichikawa, and K. Kagisaki Interleukin-6 derived from hypoxic myocytes promotes neutrophil-mediated reperfusion injury in myocardium J Thorac Cardiovasc Surg 116 1998 511 517
    • (1998) J Thorac Cardiovasc Surg , vol.116 , pp. 511-517
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.