메뉴 건너뛰기




Volumn 11, Issue 2, 2011, Pages 97-101

Pexelizumab, an Anti-C5 Complement Antibody for Primary Coronary Revascularization: A New Insight from Old Versions

Author keywords

Acute myocardial infarction; Coronary artery bypass graft surgery; Fibrinolytic therapy; Percutaneous coronary intervention; Pexelizumab

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; CREATINE KINASE MB; HEPARIN; PEXELIZUMAB; PLACEBO; COMPLEMENT COMPONENT C5; MONOCLONAL ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

EID: 83455247328     PISSN: 1871529X     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152911798347043     Document Type: Article
Times cited : (4)

References (26)
  • 2
    • 0016720281 scopus 로고
    • Consumption of classical complement components by heart subcellular membranes in vitro and in patients after acute myocardial infarction
    • Pinckard, R.N.; Olson, M.S.; Giclas, P.C.; Terry, R.; Boyer, J.T.; O'Rourke, R.A. Consumption of classical complement components by heart subcellular membranes in vitro and in patients after acute myocardial infarction. J. Clin. Invest., 1975, 56, 740-750.
    • (1975) J. Clin. Invest. , vol.56 , pp. 740-750
    • Pinckard, R.N.1    Olson, M.S.2    Giclas, P.C.3    Terry, R.4    Boyer, J.T.5    O'Rourke, R.A.6
  • 3
    • 0023931350 scopus 로고
    • Detection of the terminal complement complex in patient plasma following acute myocardial infarction
    • Langlois, P.F.; Gawryl, M.S. Detection of the terminal complement complex in patient plasma following acute myocardial infarction. Atherosclerosis, 1988, 70, 95-105.
    • (1988) Atherosclerosis , vol.70 , pp. 95-105
    • Langlois, P.F.1    Gawryl, M.S.2
  • 4
    • 0032499629 scopus 로고    scopus 로고
    • Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: Role of the terminal complement components and inhibition by anti-C5 therapy
    • Vakeva, A.P.; Agah, A.; Rollins, S.A.; Matis, L.A.; Li, L.; Stahl, G.L. Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: role of the terminal complement components and inhibition by anti-C5 therapy. Circulation, 1998, 97, 2259-2267.
    • (1998) Circulation , vol.97 , pp. 2259-2267
    • Vakeva, A.P.1    Agah, A.2    Rollins, S.A.3    Matis, L.A.4    Li, L.5    Stahl, G.L.6
  • 7
    • 0041732120 scopus 로고    scopus 로고
    • Effect of pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to fibrinolysis in acute myocardial infarction: The COMPlement inhibition in myocardial infarction treated with thromboLYtics (COMPLY) trial
    • COMPLY Investigators
    • Mahaffey, K.W.; Granger, C.B.; Nicolau, J.C.; Ruzyllo, W.; Weaver, W.D.; Theroux, P.; Hochman, J.S.; Filloon, T.G.; Mojcik, C.F.; Todaro, T.G.; Armstrong, P.W.; COMPLY Investigators. Effect of pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to fibrinolysis in acute myocardial infarction: the COMPlement inhibition in myocardial infarction treated with thromboLYtics (COMPLY) trial. Circulation, 2003, 108, 1176-1183.
    • (2003) Circulation , vol.108 , pp. 1176-1183
    • Mahaffey, K.W.1    Granger, C.B.2    Nicolau, J.C.3    Ruzyllo, W.4    Weaver, W.D.5    Theroux, P.6    Hochman, J.S.7    Filloon, T.G.8    Mojcik, C.F.9    Todaro, T.G.10    Armstrong, P.W.11
  • 8
    • 0042917638 scopus 로고    scopus 로고
    • Pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to primary percutaneous coronary intervention in acute myocardial infarction: The COMplement inhibition in Myocardial infarction treated with Angioplasty (COMMA) trial
    • COMMA Investigators
    • Granger, C.B.; Mahaffey, K.W.; Weaver, W.D.; Weaver, W.D.; Theroux, P; Hochman, J.S.; Filloon, T.G.; Rollins, S.; Todaro, T.G.; Nicolau, J.C.; Ruzyllo, W.; Armstrong, P.W.; COMMA Investigators. Pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to primary percutaneous coronary intervention in acute myocardial infarction: the COMplement inhibition in Myocardial infarction treated with Angioplasty (COMMA) trial. Circulation, 2003, 108, 1184-1190.
    • (2003) Circulation , vol.108 , pp. 1184-1190
    • Granger, C.B.1    Mahaffey, K.W.2    Weaver, W.D.3    Weaver, W.D.4    Theroux, P.5    Hochman, J.S.6    Filloon, T.G.7    Rollins, S.8    Todaro, T.G.9    Nicolau, J.C.10    Ruzyllo, W.11    Armstrong, P.W.12
  • 10
    • 79959361476 scopus 로고    scopus 로고
    • Effects of C5 complement inhibitor pexelizumab on outcome in high-risk coronary artery bypass grafting: Combined results from the PRIMO-CABG I and II trials
    • PRIMOCABG II Investigators
    • Smith, P.K.; Shernan, S.K.; Chen, J.C.; Carrier, M.; Verrier, E.D.; Adams, P.X.; Todaro, T.G.; Muhlbaier, L.H.; Levy, J.H.; PRIMOCABG II Investigators. Effects of C5 complement inhibitor pexelizumab on outcome in high-risk coronary artery bypass grafting: Combined results from the PRIMO-CABG I and II trials. J. Thorac. Cardiovasc. Surg., 2011, 142, 89-98.
    • (2011) J. Thorac. Cardiovasc. Surg. , vol.142 , pp. 89-98
    • Smith, P.K.1    Shernan, S.K.2    Chen, J.C.3    Carrier, M.4    Verrier, E.D.5    Adams, P.X.6    Todaro, T.G.7    Muhlbaier, L.H.8    Levy, J.H.9
  • 11
    • 33845981823 scopus 로고    scopus 로고
    • Pexelizumab for acute STelevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: A randomized controlled trial
    • APEX AMI Investigators
    • APEX AMI Investigators; Armstrong, P.W.; Granger, C.B.; Adams, P.X.; Hamm, C.; Holmes, D. Jr.; O'Neill, W.W.; Todaro, T.G.; Vahanian, A.; Van de Werf, F. Pexelizumab for acute STelevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: a randomized controlled trial. JAMA, 2007, 297, 43-51.
    • (2007) JAMA , vol.297 , pp. 43-51
    • Armstrong, P.W.1    Granger, C.B.2    Adams, P.X.3    Hamm, C.4    Holmes Jr., D.5    O'Neill, W.W.6    Todaro, T.G.7    Vahanian, A.8    van de Werf, F.9
  • 12
    • 78651422977 scopus 로고    scopus 로고
    • Pexelizumab may be hazardous to those with ST-segment elevation myocardial infarction undergoing primary percutaneous interventions without using glycoprotein IIb-IIIa inhibitors
    • Lin, G.M.; Chu, K.M.; Han, C.L. Pexelizumab may be hazardous to those with ST-segment elevation myocardial infarction undergoing primary percutaneous interventions without using glycoprotein IIb-IIIa inhibitors. Int. J. Cardiol., 2011, 146, 280-282.
    • (2011) Int. J. Cardiol. , vol.146 , pp. 280-282
    • Lin, G.M.1    Chu, K.M.2    Han, C.L.3
  • 13
    • 0029029540 scopus 로고
    • The Fluid-phase SC5b-9 Terminal Complement Complex Binds to the GPIIb/IIIa Complex of Thrombin-stimulated Human Blood Platelets Inhibiting Platelets Aggregation
    • Røger, M.; Høgåsen, K.; Holme, P.A.; Halstensen, T.S.; Mollnes, T.E.; Hovig, T. The Fluid-phase SC5b-9 Terminal Complement Complex Binds to the GPIIb/IIIa Complex of Thrombin-stimulated Human Blood Platelets Inhibiting Platelets Aggregation. Platelet, 1995, 6, 160-168.
    • (1995) Platelet , vol.6 , pp. 160-168
    • Røger, M.1    Høgåsen, K.2    Holme, P.A.3    Halstensen, T.S.4    Mollnes, T.E.5    Hovig, T.6
  • 14
    • 79951953841 scopus 로고    scopus 로고
    • Predictors, moderators and mediators for the effectiveness of pexelizumab treatment in patients undergoing primary coronary revascularization
    • Lin, G.M.; Li, Y.H.; Wen, S.H.; Chen, S.Y.; Chu, K.M.; Han, C.L. Predictors, moderators and mediators for the effectiveness of pexelizumab treatment in patients undergoing primary coronary revascularization. Int. J. Cardiol., 2011, 147, 340-341.
    • (2011) Int. J. Cardiol. , vol.147 , pp. 340-341
    • Lin, G.M.1    Li, Y.H.2    Wen, S.H.3    Chen, S.Y.4    Chu, K.M.5    Han, C.L.6
  • 15
    • 0023020183 scopus 로고
    • The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations
    • Baron, R. M; Kenny, D.A. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J. Pers. Soc. Psychol., 1986, 51, 1173-1182.
    • (1986) J. Pers. Soc. Psychol. , vol.51 , pp. 1173-1182
    • Baron, R.M.1    Kenny, D.A.2
  • 18
    • 77954159224 scopus 로고    scopus 로고
    • Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: A meta-regression analysis of randomized trials
    • Lin, G.M., Han, C.L. Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-regression analysis of randomized trials. Eur. Heart J., 2010, 31, 753-754.
    • (2010) Eur. Heart J. , vol.31 , pp. 753-754
    • Lin, G.M.1    Han, C.L.2
  • 19
  • 20
    • 79956324595 scopus 로고    scopus 로고
    • Controversies with On-TIME 2
    • Lin, G.M.; Li, Y.H.; Chu, K.M., Han, C.L. Controversies with On-TIME 2. Heart, 2011, 97, 1026.
    • (2011) Heart , vol.97 , pp. 1026
    • Lin, G.M.1    Li, Y.H.2    Chu, K.M.3    Han, C.L.4
  • 21
    • 49149128492 scopus 로고    scopus 로고
    • Ongoing Tirofiban In Myocardial infarction Evaluation (On-TIME) 2 study group. Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): A multicentre, double-blind, randomized controlled trial
    • Van't Hof, A.W.; Ten Berg, J.; Heestermans, T.; Dill, T; Funck, R.C.; van Werkum, W.; Dambrink, J.H.; Suryapranata, H.; van Houwelingen, G.; Ottervanger, J.P.; Stella, P; Giannitsis, E.; Hamm, C. Ongoing Tirofiban In Myocardial infarction Evaluation (On-TIME) 2 study group. Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): a multicentre, double-blind, randomized controlled trial. Lancet, 2008, 372, 537-546.
    • (2008) Lancet , vol.372 , pp. 537-546
    • van't Hof, A.W.1    Ten Berg, J.2    Heestermans, T.3    Dill, T.4    Funck, R.C.5    van Werkum, W.6    Dambrink, J.H.7    Suryapranata, H.8    van Houwelingen, G.9    Ottervanger, J.P.10    Stella, P.11    Giannitsis, E.12    Hamm, C.13
  • 23
    • 0022507422 scopus 로고
    • Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery
    • George, J.N.; Pickett, E.B.; Saucerman, S. Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery. J. Clin. Invest., 1986, 78, 340-348.
    • (1986) J. Clin. Invest. , vol.78 , pp. 340-348
    • George, J.N.1    Pickett, E.B.2    Saucerman, S.3
  • 25
  • 26
    • 79960395020 scopus 로고    scopus 로고
    • A critical Appraisal of pexelizumab treatment in patients undergoing coronary artery bypass grafting
    • Lin, G.M.; Li, Y.H.; Han, C.L. A critical Appraisal of pexelizumab treatment in patients undergoing coronary artery bypass grafting. J. Thorac. Cardiovasc. Surg., 2011, 142, 472.
    • (2011) J. Thorac. Cardiovasc. Surg. , vol.142 , pp. 472
    • Lin, G.M.1    Li, Y.H.2    Han, C.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.