Angiotensin-(1-7) treatment ameliorates angiotensin II-induced apoptosis of human umbilical vein endothelial cells

Clinical and Experimental Pharmacology and Physiology

Volumn 39, Issue 12, 2012, Pages 1004-1010

  Yang, Hui Yu ^a   Bian, Yun Fei ^a   Zhang, Hua Ping ^a   Gao, Fen ^a   Xiao, Chuan Shi ^a   Liang, Bin ^a   Li, Jin ^a   Zhang, Na Na ^a   Yang, Zhi Ming ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin II; Angiotensin (1 7); Apoptosis; Human umbilical vein endothelial cells; Lectin like oxidized low density lipoprotein receptor 1

Indexed keywords

ACRIDINE ORANGE; ANGIOTENSIN II; ANGIOTENSIN[1-7]; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; CASPASE 3; ETHIDIUM BROMIDE; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PROPIDIUM IODIDE; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION;

ANGIOTENSIN II; ANGIOTENSIN-(1-7); APOPTOSIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; LECTIN-LIKE OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR-1;

ANGIOTENSIN I; ANGIOTENSIN II; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL CULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FLOW CYTOMETRY; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SCAVENGER RECEPTORS, CLASS E; UP-REGULATION;

EID: 84870284423     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12016     Document Type: Article

References (26)

1. Xue H, Zhou L, Yuan P et al. Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells. Regul. Pept. 2012; 177: 12-20.
2. Sata M, Fukuda D. Crucial role of renin-angiotensin system in the pathogenesis of atherosclerosis. J. Med. Invest. 2010; 57: 12-25.
3. Kim YC, Day RM. Ang II regulates activation of Bim via Rb/E2F1 during apoptosis: Involvement of interaction between AMPKβ1/2 and Cdk4. Am. J. Physiol. Lung Cell. Mol. Physiol. 2012; 303: L228-38.
4. Mehta JL, Chen J, Hermonat PL, Romeo F, Novelli G. Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): A critical player in the development of atherosclerosis and related disorders. Cardiovasc. Res. 2006; 69: 36-45.
5. Lu J, Yang JH, Burns AR et al. Mediation of electronegative low-density lipoprotein signaling by LOX-1: A possible mechanism of endothelial apoptosis. Circ. Res. 2009; 104: 619-27.
6. Li D, Mehta JL. Intracellular signaling of LOX-1 in endothelial cell apoptosis. Circ. Res. 2009; 104: 566-8.
7. Chen J, Mehta JL, Haider N, Zhang X, Narula J, Li D. Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells. Circ. Res. 2004; 94: 370-6.
8. Ueno T, Fukuda N, Tsunemi A et al. A novel gene silencer, pyrrole-imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function. J. Hypertens. 2009; 27: 508-16.
9. Bindom SM, Lazartigues E. The sweeter side of ACE2: Physiological evidence for a role in diabetes. Mol. Cell. Endocrinol. 2009; 302: 193-202.
10. Yousif MH, Dhaunsi GS, Makki BM, Qabazard BA, Akhtar S, Benter IF. Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes. Pharmacol. Res. 2012; 66: 269-75.
11. Ferreira AJ, Santos RA, Almeida AP. Angiotensin-(1-7): Cardioprotective effect in myocardial ischaemia/reperfusion. Hypertension 2001; 38: 665-8.
12. Ferreira AJ, Santos RA, Almeida AP. Angiotensin-(1-7) improves the post-ischemic function in isolated perfused rat hearts. Braz. J. Med. Biol. Res. 2002; 35: 1083-90.
13. Grobe JL, Mecca AP, Lingis M et al. Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7). Am. J. Physiol. Heart Circ. Physiol. 2007; 292: H736-42.
14. Kucharewicz I, Pawlak R, Matys T, Chabielska E, Buczko W. Angiotensin-(1-7): An active member of the renin-angiotensin system. J. Physiol. Pharmacol. 2002; 53: 533-40.
15. 2+ in mesangial cells. Eur. J. Pharmacol. 2001; 414: 165-75.
16. Schindler C, Bramlage P, Kirch W, Ferrario CM. Role of the vasodilator peptide angiotensin-(1-7) in cardiovascular drug therapy. Vasc. Health Risk Manag. 2007; 3: 125-37.
17. Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 1973; 52: 2745-56.
18. Harach HR, Jasani B, Williams ED. Factor VIII as a marker of endothelial cells in follicular carcinoma of the thyroid. J. Clin. Pathol. 1983; 36: 1050-4.
19. 1-dependent oxidant-sensitive decrement of nitric oxide availability. Arterioscler. Thromb. Vasc. Biol. 2003; 23: 1218-23.
20. + ATPase in human umbilical vein endothelial cells. J. Endocrinol. 1997; 155: 587-93.
21. Geng CX, Zeng ZC, Wang JY. Docetaxel inhibits SMMC-7721 human hepatocellular carcinoma cells growth and induces apoptosis. World J. Gastroenterol. 2003; 9: 696-700.
22. Bombeli T, Schwartz BR, Harlan JM. Endothelial cells undergoing apoptosis become proadhesive for nonactivated platelets. Blood 1999; 93: 3831-8.
23. Bian YF, Yang HY, Yang ZM, Gao F, Zhang NN, Xiao CS. Amlodipine treatment prevents angiotensin II-induced human umbilical vein endothelial cell apoptosis. Arch. Med. Res. 2011; 42: 22-7.
24. Uhal BD, Li X, Xue A, Gao X, Abdul-Hafez A. Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1-7/Mas axis. Am. J. Physiol. Lung Cell. Mol. Physiol. 2011; 301: L269-74.
25. Wang K, Hu X, Du C, Tu S, Zhang F, Xie X. Angiotensin-(1-7) suppresses the number and function of the circulating fibrocytes by upregulating endothelial nitric oxide synthase expression. Mol. Cell. Biochem. 2012; 365: 19-27.
26. Menon J, Soto-Pantoja DR, Callahan MF, Cline JM, Ferrario CM, Tallant EA, Gallagher PE. Angiotensin-(1-7) inhibits growth of human lung adenocarcinoma xenografts in nude mice through a reduction in cyclooxygenase-2. Cancer Res. 2007; 67: 2809-15.