HIF-1α regulation in mammalian hibernators: Role of non-coding RNA in HIF-1α control during torpor in ground squirrels and bats

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology

Volumn 182, Issue 6, 2012, Pages 849-859

  Maistrovski, Yulia ^a   Biggar, Kyle K ^a   Storey, Kenneth B ^a  

^a CARLETON UNIVERSITY   (Canada)

Author keywords

Antisense RNA; Hibernation; HIF 1 ; Hypoxia response; MicroRNA; Non coding RNA

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICRORNA; UNTRANSLATED RNA;

ANIMAL; ARTICLE; BAT; BIOSYNTHESIS; GENETICS; HIBERNATION; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SCIURIDAE;

ANIMALS; BASE SEQUENCE; CHIROPTERA; HIBERNATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICRORNAS; RNA, UNTRANSLATED; SCIURIDAE;

ANIMALIA; CHIROPTERA; MAMMALIA; MYOTIS LUCIFUGUS; RODENTIA; SCIURIDAE; SPERMOPHILUS; SPERMOPHILUS TRIDECEMLINEATUS;

EID: 84870266566     PISSN: 01741578     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00360-012-0662-y     Document Type: Article

References (37)

1. Adams JM, Difazio LT, Rolandelli RH, Lujan JJ, Hasko GY, Csoka B, Selmeczy Z, Nemeth ZH (2009) HIF-1: a key mediator in hypoxia. Acta Physiol Hungarica 96: 19-28.
2. Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
3. Biggar KK, Storey KB (2011) The emerging roles of microRNAs in the molecular responses of metabolic rate depression. J Mol Cell Biol 3: 167-175.
4. Biggar KK, Kornfeld SF, Storey KB (2011) Amplification and sequencing of mature microRNAs in uncharacterized animal models using stem-loop reverse transcription-polymerase chain reaction. Anal Biochem 416: 231-233.
5. Bos R (2001) Levels of hypoxia-inducible factor-1α during breast carcinogenesis. J Natl Cancer Inst 93: 309-314.
6. Buck CL, Barnes BM (2000) Effects of ambient temperature on metabolic rate, respiratory quotient, and torpor in an arctic hibernator. Am J Physiol Regul Integr Comp Physiol 279: R255-R262.
7. Buck MJ, Squire TL, Andrews MT (2002) Coordinate expression of the PDK4 gene: a means of regulating fuel selection in a hibernating mammal. Physiol Genomics 8: 5-13.
8. Chun YS, Kim MS, Park JW (2002) Oxygen-dependent and -independent regulation of HIF-1 alpha. J Korean Med Sci 17: 581-588.
9. Dalmay T, Edwards DR (2006) MicroRNAs and the hallmarks of cancer. Oncogene 25: 6170-6175.
10. Dirnagl U, Becker K, Meisel A (2006) Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use. Lancet Neurol 8: 398-412.
11. Drew KL, Harris MB, LaManna JC, Smith MA, Zhu XW, Ma YL (2004) Hypoxia tolerance in mammalian heterotherms. J Exp Biol 207: 3155-3162.
12. MAPK regulation of transcription factor targets in muscle and heart of hibernating bats, Myotis lucifugus. Cell Biochem Function 25: 759-765.
13. Faghihi MA, Wahlestedt CW (2009) Regulatory roles of natural antisense transcripts. Nature Rev Mol Cell Biol 10: 637-644.
14. Frerichs KU, Kennedy C, Sokoloff L, Hallenbeck JM (1994) Local cerebral blood flow during hibernation, a model of natural tolerance to "cerebral ischemia". J Cereb Blood Flow Metab 14: 193-205.
15. Geiser F (1988) Reduction of metabolism during hibernation and daily torpor in mammals and birds: temperature effect or physiological inhibition? J Comp Physiol 158: 25-37.
16. Good L (2003) Translation repression by antisense sequences. Cell Mol Life Sci 60: 854-861.
17. Ho EC, Donaldson ME, Saville BJ (2010) Detection of antisense RNA transcripts by strand-specific RT-PCR. Meth Mol Biol 630: 125-138.
18. 2-dependent degradation domain via the ubiquitin proteasome pathway. Biochemistry 95: 7987-7992.
19. Kapranov P, Willingham AT, Gingeras TR (2007) Genome-wide transcription and the implications for genomic organization. Nature Rev Genetics 8: 413-423.
20. Loor G, Schumacker PT (2008) Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion. Cell Death Differ 15: 686-690.
21. McMullen DC, Hallenbeck JM (2010) Regulation of Akt during torpor in the hibernating ground squirrel, Ictidomys tridecemlineatus. J Comp Physiol B 180(6): 927-934.
22. Mercer TR, Marcel MD, Mattick JS (2009) Long non-coding RNAs: insight into functions. Nature Rev Genetics 10: 155-159.
23. Morin P, Storey KB (2005) Cloning and expression of hypoxia-inducible factor 1a from the hibernating ground squirrel, Spermophilus tridecemlineatus. Biochim Biophys Acta 1729: 32-40.
24. Morin P, Dubuc A, Storey KB (2008) Differential expression of microRNA species in organs of hibernating ground squirrels: a role in translational suppression during torpor. Biochim Biophys Acta 1779: 628-633.
25. Rossignol F, Vache C, Clottes E (2002) Natural antisense transcripts of hypoxia-inducible factor 1alpha are detected in different normal and tumour human tissues. Intl J Genes Genom 299: 135-140.
26. Rossignol F, de Laplanche E, Mounier R, Bonnefont J, Cayre A, Godinot C, Simonnet H, Clottes E (2004) Natural antisense transcripts of HIF-1alpha are conserved in rodents. Intl J Genes Genom 339: 121-130.
27. Semenza GL (2003) Targeting HIF-1 for cancer therapy. Nature Rev 3: 721-732.
28. Semenza GL (2007) Hypoxia-inducible factor-1 (HIF-1) pathway. Sci STKE 407: cm8.
29. Singh J, Nagaraju J (2008) In silico prediction and characterization of microRNAs from red flour beetle (Tribolium castaneum). Insect Mol Biol 17: 427-436.
30. Storey KB (2003) Mammalian hibernation: transcriptional and translational controls. Adv Exp Med Biol 543: 21-38.
31. Storey KB, Storey JM (2004) Mammalian hibernation: biochemical adaptation and gene expression. In: Storey KB (ed) Functional metabolism: regulation and adaptation. Wiley-Liss, Hoboken, pp 443-471.
32. Storey KB, Storey JM (2010) Metabolic rate depression: the biochemistry of mammalian hibernation. In: Makowski GS (ed) Advances in clinical chemistry. Elsevier Inc., Burlington, pp 77-108.
33. Thrash-Bingham CA, Tartof KD (1999) aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia. J Natl Cancer Inst 91: 143-151.
34. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, Prueitt RL, Yanaihara N, Lanza G, Scarpa A, Vecchione A, Negrini M, Harris CC, Croce CM (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261.
35. Wang LCH (1989) Ecological, physiological and biochemical aspects of torpor in mammals and birds. In: Wang LCH (ed) Advances in comparative and environmental physiology, vol 4. Springer, Heidelberg, pp 361-401.
36. Watanabe Y, Yachie N, Numata K, Saito R, Kanai A, Tomita M (2006) Computational analysis of microRNA targets in Caenorhabditis elegans. Gene 365: 2-10.
37. Wenger RH, Kvietikova I, Rolfs A, Gassmann M, Marti HH (1997) Hypoxia-inducible factor-1 alpha is regulated at the post-mRNA level. Kidney Intl 51: 560-563.