Antidiabetic and antiacetylcholinesterase effects of ethyl acetate fraction of Chaenomeles sinensis (Thouin) Koehne fruits in streptozotocin-induced diabetic rats

Experimental and Toxicologic Pathology

Volumn 65, Issue 1-2, 2013, Pages 55-60

  Sancheti, Sandesh ^a   Sancheti, Shruti ^a   Seo, Sung Yum ^a,b  

^a Kongju National University   (South Korea)

^b Korean Collection of Herbal Extracts Inc   (South Korea)

Author keywords

Antiacetylcholinesterase; Antidiabetic; Antioxidant; Chaenomeles sinensis; Diabetic rats

Indexed keywords

ACETYLCHOLINESTERASE; ALANINE AMINOTRANSFERASE; ALPHA GLUCOSIDASE; AMYLASE; ANTIDIABETIC AGENT; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CHAENOMELES SINENSIS EXTRACT; CHOLESTEROL; GLIBENCLAMIDE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PLANT EXTRACT; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CHAENOMELES SINENSIS; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG DOSE COMPARISON; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; MALE; NONHUMAN; RAT; ROSACEAE; STREPTOZOCIN DIABETES;

ACETATES; ACETYLCHOLINESTERASE; ALPHA-AMYLASES; ALPHA-GLUCOSIDASES; ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; CHOLINESTERASE INHIBITORS; DIABETES MELLITUS, EXPERIMENTAL; ERYTHROCYTES; FRUIT; HYPOGLYCEMIC AGENTS; INTESTINES; LIPASE; LIPID METABOLISM; MALE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; ROSACEAE; STREPTOZOCIN;

PSEUDOCYDONIA SINENSIS; RATTUS;

EID: 84870243267     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2011.05.010     Document Type: Article

References (35)

1. Ahmed I., Lakhani M.S., Gillet M., John A., Raza H. Hypotriglyceridemic and hypocholesterolemic effects of antidiabetic Momordica charantia (Kerela) fruit extract in streptozotocin-induced diabetic rats. Diabetes Res Clin Pract 2001, 51:155-161.
2. American Diabetes Association Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 2007, 30:S42-S46.
3. Ardestani A., Yazdanparast R. Flavonoids as potential therapeutic agents for type 1 diabetes. Med Hypotheses 2007, 69:955.
4. Aslan M., Orhan D.D., Orhan N., Sezik E., Yesilada E. A study of antidiabetic and antioxidant effects of Helichrysum graveolens capitulums in streptozotocin-induced diabetic rats. J Med Food 2007, 10:396-400.
5. Bafna M., Sancheti S., Sancheti S., Seo S.Y. Antioxidant and α-glucosidase inhibitory properties of Carpesium abrotanoides L. J Med Plants Res 2010, 15:1547-1553.
6. Blum J., Fridovich I. Inactivation of glutathione peroxidase by superoxide radicals. Arch Biochem Biophys 1985, 240:500-550.
7. Cheng A.Y.Y., Josse R.G. Intestinal absorption inhibitors for type 2 diabetes mellitus: prevention and treatment. Drug Discovery Today: Ther Strat 2004, 1:6-201.
8. Doroshow J.H, Locker G.Y., Myers C.E. Enzymatic defenses of the mouse heart against reactive oxygen metabolites. J Clin Invest 1980, 65:128-135.
9. Ellman G.L., Courtney K.D., Andres V., Feather-Stone R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961, 7:88-95.
10. Gholamhoseiniana A., Fallaha H., Sharififar F. Inhibitory effect of methanol extract of Rosa damascena Mill. flowers on α-glucosidase activity and postprandial hyperglycemia in normal and diabetic rats. Phytomedicine 2009, 16:935-941.
11. Gupta R.K., Kesari A.N., Murthy P.S., Chandra R., Tandon V., Watal G. Hypoglycemic and antidiabetic effect of ethanolic extract of leaves of Annona squamosa L. in experimental animals. J Ethnopharmacol 2005, 99:75-81.
12. Hollander P.A., Elbein S.C., Hirsch I.B., Kelley D., McGill J., Taylor T., et al. Role of orlistat in the treatment of obese patients with type 2 diabetes. A 1-year randomized double-blind study. Diabetes Care 1998, 21:1288-1294.
13. Kamboj S.S., Chopra K., Sandhir R. Neuroprotective effect of N-acetylcysteine in the development of diabetic encephalopathy in streptozotocin-induced diabetes. Metab Brain Dis 2008, 23:427-443.
14. Kannel W.B., Mc Gee D.L. Diabetes and cardiovascular risk factors: the Framingham study. Circulation 1979, 59:8-13.
15. Kavak S., Ayaz L., Emre M., Inal T., Tamer L., Günay I. The effects of rosiglitazone on oxidative stress and lipid profile in left ventricular muscles of diabetic rats. Cell Biochem Funct 2008, 26:478-485.
16. Kelly J.J., Tsai A.C. Effect of pectin, gum Arabic and agar on cholesterol absorption, synthesis and turnover in rats. J Nutr 1978, 108:630-639.
17. Kim G.N., Shin J.G., Jang H.D. Antioxidant and antidiabetic activity of Dangyuja (Citrus grandis Osbeck) extract treated with Aspergillus saitoi. Food Chem 2009, 117:35-41.
18. Kim J.H., Kim H.J., Park H.W., Youn S.H., Choi D.Y., Shin C.S. Developmentof inhibitors against lipase and α-glucosidase from derivatives of monascus pigment. FEMS Microbiol Lett 2007, 276:93-98.
19. Klein G., Kim J., Himmeldirk K., Cao Y., Chen X. Antidiabetes and anti-obesity activity of Lagerstroemia speciosa. eCAM 2007, 4:401-407.
20. Kritchevsky D. Fiber, lipids and atherosclerosis. Am J Clin Nutr 1978, 31:S65-S74.
21. Kuhad A., Sethi R., Chopra K. Lycopene attenuates diabetes-associated cognitive decline in rats. Life Sci 2008, 83:128-134.
22. Larner J. Insulin and oral hypoglycemic drugs; glucagons. The pharmacological basis of therapeutics 1985, 1504-1507. Macmillan Publishing Co., Inc., New York. 7th ed. A.G. Gilman, L.S. Goodman, T.W. Rall, F. Murad (Eds.).
23. Lowe M.E. Structure and function of pancreatic lipase and colipase. Annu Rev Nutr 1997, 17:141-158.
24. Marles R.J., Fransworth N.R. Antidiabetic plants and their active constituents. Phytomedicine 1995, 2:137-189.
25. McCall A.L. The impact of diabetes on the CNS. Diabetes 1992, 41:557-570.
26. Nakahara K., Izumi R., Kodama T., Kiso Y., Tanaka T. Inhibition of postprandial hyperglycaemia by oolong tea extract (OTE). Phytother Res 1994, 8:433-435.
27. Papandreou M.A., Dimakopoulou A., Linardaki Z.I., Cordopatis P., Zacas D.K., Margarity M., et al. Effect of a polyphenol-rich wild blueberry extract on cognitive performance of mice, brain antioxidant markers and acetylcholinesterase activity. Behav Brain Res 2009, 198:352-358.
28. Park J.M., Bong H.Y., Jeong H.I., Kim Y.K., Kim J.Y., Kwon O. Postprandial hypoglycemic effect of mulberry leaf in Goto-Kakizaki rats and counterpart control Wistar rats. Nutr Res Pract 2009, 3:272-278.
29. Rhabasa-Lhoret R., Chiasson J.L. α-Glucosidase inhibitors. International Textbook of Diabetes Mellitus 2004, 1:901-914. John Wiley & Sons Ltd. 3rd ed.
30. Sancheti S., Sancheti S., Bafna M., Seo S.Y. Antihyperglycemic, antihyperlipidemic, and antioxidant effects of Chaenomeles sinensis fruit extract in streptozotocin-induced diabetic rats. Eur Food Res Technol 2010, 231:415-421.
31. Sancheti S., Sancheti S., Um B.H., Seo S.Y. 1,2,3,4,6-Penta-O-galloyl-β-d-glucose: a cholinesterase inhibitor from Terminalia chebula. S Afr J Bot 2010, 76:285-288.
32. Schmatz R., Mazzanti C.M., Spanevello R., Stefanello N., Gutierres J., Corrêa M., et al. Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats. Eur J Pharmacol 2009, 610:42-48.
33. Tawta M., Ikeda M., Kodama Y., Aida K., Onaya T. A type 2 diabetic patient with liver dysfunction due to human insulin. Diabetes Res Clin Pract 2000, 49:17-21.
34. WHO Expert committee on diabetes mellitus. Technical Report Series 646 1980, World Health Organization, Geneva.
35. Zhang L.H., Xu H.D., Li S.F. Effects of micronization on properties of Chaenomeles sinensis (Thouin) Koehne fruit powder. Innov Food Sci Emerg Technol 2009, 10:633-637.