Antioxidant and antidiabetic activity of Dangyuja (Citrus grandis Osbeck) extract treated with Aspergillus saitoi

Food Chemistry

Volumn 117, Issue 1, 2009, Pages 35-41

  Kim, Gyo Nam ^a   Shin, Jung Geun ^a   Jang, Hae Dong ^a  

^a Hannam University   (South Korea)

Author keywords

Antidiabetic activity; Antioxidant activity; Dangyuja extract; ORAC; Rat intestinal glucosidase inhibition

Indexed keywords

8 HYDROXYHESPERITIN; ALPHA GLUCOSIDASE; AMYLASE; AURANTIIN; BACTERIAL ENZYME; CARTHAMIDIN; DANGYUJA EXTRACT; FLAVANONE DERIVATIVE; GLYCOSIDE; HESPERETIN; HESPERIDIN; HESPERIDINASE; ISOCARTHAMIDIN; NARINGENIN; NARINGINASE; NARIRUTIN; NEOHESPERIDIN; OXYGEN RADICAL; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; ASPERGILLUS; ASPERGILLUS SAITOI; ASSAY; DANGYUJA; DNA SUPERCOILING; ENZYME ACTIVITY; ENZYME INHIBITION; FERMENTATION; NONHUMAN; OXYGEN RADICAL ABSORBANCE CAPACITY; PUMMELO; RAT; SUPERCOILED DNA STRAND SCISSION ASSAY;

ASPERGILLUS SAITOI; CITRUS; CITRUS MAXIMA; RATTUS; SUS;

EID: 67349232382     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2009.03.072     Document Type: Article

References (31)

1. Aruoma O. Deoxyribose assay for detecting hydroxyl radicals. Methods in Enzymology 233 (1994) 57-66
2. Cao G., Sofic E., and Prior R.L. Antioxidant and prooxidant behavior of flavonoids: Structure-activity relationships. Free Radical Biology and Medicine 22 (1997) 747-760
3. Cheng A.Y.Y., and Josse R.G. Intestinal absorption inhibitors for type 2 diabetes mellitus: Prevention and treatment. Drug Discovery Today: Therapeutic Strategies 1 (2004) 201-206
4. Chung S.K., Kim S.H., Choi Y.H., Song E.Y., and Kim S.H. Status of Citrus fruit production and view of utilization in Cheju. Food Industry and Nutrition 5 (2000) 42-52
5. Di Majo D., Giammanco M., La Guardia M., Tripoli E., Giammanco S., and Finotti E. Flavonones in Citrus fruit: Structure-antioxidant activity relationship. Food Research International 38 (2005) 1161-1166
6. Gao H., and Kawabata J. Importance of the B ring and its substitution on the α-glucosidase inhibitory activity of Baicalein, 5,6,7-trihydroxyflavone. Bioscience Biotechnology Biochemistry 68 (2004) 1858-1864
7. Gao H., and Kawabata J. α-Glucosidase inhibition of 6-hydroxyflavones. Part 3: Synthesis and evaluation of 2,3,4-trihydroxybenzoyl-containing flavonoid analogs and 6-aminoflavones as α-glucosidase inhibitors. Bioorganic and Medicinal Chemistry 13 (2005) 1661-1671
8. Halliwell B., Aeschbach R., Lo{combining double acute accent}liger J., and Aruoma O.I. The characterization of antioxidants. Food and Chemical Toxicology 33 (1995) 601-617
9. Hollander P. Safety profile of acarbose, an α-glucosidsase inhibitor. Drugs 44 Suppl. 2 (1992) 21-23
10. Horii S., Fukasse K., Matsuo T., Kameda K., Asano N., and Masui Y. Synthesis and α-d-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potent oral antidiabetic agents. Journal of Medicinal Chemistry 29 (1987) 1038-1046
11. Jung U.J., Lee M.K., Park Y.B., Kang M.A., and Choi M.S. Effect of Citrus flavonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice. The International Journal of Biochemistry and Cell Biology 38 (2006) 1134-1145
12. Kanaze F.I., Kokkalou E., Georgarakis M., and Niopas I. Validated high-performance liquid chromatographic method utilizing solid-phase extraction for the simultaneous determination of naringenin and hesperetin in human plasma. Journal of Chromatography B 801 (2004) 363-367
13. Kim G.N., Jung H.M., and Jang H.D. Structure-activity relationship of citrus hydroxyflavanone glycosides and their aglycones against oxidative damage in HepG2 cells. Journal of Clinical Biochemistry and Nutrition 43 Suppl. 1 (2008) 508-511
14. Krentz A.J., and Bailey C.J. Oral antidiabetic agents current role in type 2 diabetes mellitus. Drugs 65 (2005) 385-411
15. Kurihara H., Fukami H., Asami S., Totoda Y., Nakai M., Shibata H., et al. Effects of oolong tea on plasma antioxidative capacity in mice loaded with restraint stress assessed using the oxygen radical absorbance capacity (ORAC) assay. Biological Pharmacology Bulletin 27 (2004) 1093-1098
16. Kwon Y.I., Vattem D.A., and Shetty K. Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension. Asian Pacific Journal of Clinical Nutrition 15 (2006) 107-118
17. Lee S.H., Jeong T.S., Park Y.B., Kwon Y.K., Choi M.S., and Bok S.Ha. Hypocholesterolemic effect of hesperetin mediated by inhibition of 3-hydroxy-3-methylgultaryl coenzyme A reductase and acyl coenzyme A: Cholesterol acyltransferase in rats fed high-cholesterol diet. Nutrition Research 19 (1999) 1245-1258
18. Lee E.J., Kwon Y.I., Shetty K., and Jang H.D. Antioxidant activity of Rhodiola rosea extract on human low-density lipoprotein oxidation and DNA strand scission. Food Science and Biotechnology 13 (2004) 814-820
19. +-glucose cotransporter by naringenin. The International Journal of Biochemistry and Cell Biology 38 (2006) 985-995
20. Lim K.T., Hu C., and Kitts D.D. Antioxidant activity of a Rhus verniciflua Stokes ethanol extract. Food and Chemical Toxicology 39 (2001) 229-237
21. Lim H.K., Yoo E.S., Moon J.Y., Jeon Y.J., and Cho S.K. Antioxidant activity of extracts from Dangyuja (Citrus grandis Osbeck) fruits produced in Jeju Island. Food Science and Biotechnology 15 (2006) 312-316
22. Miyake Y., Minato K., Fukumoto S., Yamamoto K., Oya-Ito T., Kawakishi S., et al. New potent antioxidative hydroxyflavanones produced with Aspergillus saitoi from flavanone glycoside in Citrus fruit. Bioscience Biotechnology Biochemistry 67 (2003) 1443-1450
23. Murao S., Ohyyama K., and Ogura S. Isolation of amylase inhibitor-producing microorganism. Agricultural Biological Chemistry 41 (1977) 919-924
24. Ohta T., Sasaki S., Oohori T., Yoshikawa S., and Kurihara H. Α-glucosidase inhibitory activity of a 70% methanol extract from Ezoishige (Pelvetia babingtonii de Toni) and its effect on the elevation of blood glucose level in rats. Bioscience Biotechnology Biochemistry 66 (2002) 1552-1554
25. Puri M., Banerjee A., and Banerjee U.C. Optimization of process parameters for the production of naringinase by Aspergillus niger MTCC 1344. Process Biochemistry 40 (2005) 195-201
26. Rhyu M.R., Kim E.Y., Bae I.Y., and Park Y.K. Contents of naringin, hesperidin and neohesperidin in premature Korean Citrus fruits. Korean Journal of Food Science and Technology 34 (2002) 132-135
27. Sakata K., Hirose Y., Qiao Z., Tanaka T., and Mori H. Inhibition of inducible isoforms of cyclooxygenase and nitric oxide synthase by flavonoid hesperidin in mouse macrophage cell line. Cancer Letters 199 (2003) 139-145
28. Schmidt D., Former H., Junge B., Muller M., Wingender W., and Trusheit E. Α-glucosidase inhibitor: New complex oligosaccharides of microbial origin. Naturwissenschaften 64 (1977) 535-536
29. Son H.S., Kim H.S., Kwon T.B., and Ju J.S. Isolation, purification and hypotensive effect of bioflavonoids in Citrus sinensis. Journal of Korean Society of Food and Nutrition 21 (1992) 136-142
30. Watanabe K., Furumai T.T., Sudoh M., Tokose M., and Maruyama H.B. New alpha-amylase inhibitor, trestatins. IV. Taxonomy of the producing strains and fermentation oftrestatin A. Journal of Antibiotics 37 (1984) 479-486
31. Yang M.H., and Schaich K.M. Factors affecting DNA damage caused by lipid hydroperoxides and aldehydes. Free Radical Biology and Medicine 20 (1996) 225-236