Recombinant trehalose-6-phosphate phosphatase of Brugia malayi cross-reacts with human Wuchereria bancrofti immune sera and engenders a robust protective outcome in mice

Microbes and Infection

Volumn 14, Issue 14, 2012, Pages 1330-1339

  Kushwaha, Susheela ^a   Singh, Prashant Kumar ^a   Gupta, Jyoti ^a   Soni, Vishal Kumar ^a   Misra Bhattacharya, Shailja ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Immunogenicity; Lymphatic filariasis; Macrophages; Trehalose 6 phosphate phosphatase

Indexed keywords

ANTISERUM; CD4 ANTIGEN; CD8 ANTIGEN; FREUND ADJUVANT; GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; PHOSPHATASE; TREHALOSE; TREHALOSE 6 PHOSPHATE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BIOINFORMATICS; BRUGIA MALAYI; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COMPUTER MODEL; CONTROLLED STUDY; CROSS REACTION; HELPER CELL; IMMUNIZATION; IMMUNOGENICITY; LARVA; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; WUCHERERIA BANCROFTI;

AMINO ACID SEQUENCE; ANALYSIS OF VARIANCE; ANIMALS; ANTIBODIES, HELMINTH; BRUGIA MALAYI; CELL PROLIFERATION; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CROSS REACTIONS; CYTOKINES; ELEPHANTIASIS, FILARIAL; HELMINTH PROTEINS; IMMUNOGLOBULIN G; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PHOSPHORIC MONOESTER HYDROLASES; RECOMBINANT PROTEINS; VACCINES, SYNTHETIC; WUCHERERIA BANCROFTI;

BRUGIA MALAYI; MAMMALIA; MUS; WUCHERERIA BANCROFTI;

EID: 84870239555     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2012.08.006     Document Type: Article

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