Design and synthesis of procollagen C-proteinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 24, 2012, Pages 7397-7401

  Turtle, Eric ^a   Chow, Nicholas ^a   Yang, Charles ^a   Sosa, Sergio ^a   Bauer, Udo ^a   Brenner, Mitch ^a   Solow Cordero, David ^a   Ho, Wen Bin ^a  

^a FIBROGEN INC   (United States)

Author keywords

Fibrosis; Hydroxamate; Procollagen C proteinase

Indexed keywords

COLLAGEN; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; METALLOPROTEINASE INHIBITOR; PROCOLLAGEN C PROTEINASE; PROCOLLAGEN C PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; IC 50;

3T3-L1 CELLS; ANIMALS; BONE MORPHOGENETIC PROTEIN 1; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; HUMANS; MICE; MOLECULAR STRUCTURE; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84870238534     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.10.067     Document Type: Article

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